The RET proto-oncogene encodes a receptor tyrosine kinase for members of the glial cell line-derived neurotrophic factor (GDNF) family of extracellular...
21 KB (2,385 words) - 03:45, 16 December 2023
Hirschsprung's disease (section RET proto-oncogene)
to be associated with Hirschsprung's disease[citation needed] The RET proto-oncogene accounts for the highest proportion of both familial and sporadic...
36 KB (3,881 words) - 05:56, 31 August 2024
RET kinase inhibitors are a type of targeted cancer treatment that block abnormally activated RET proto-oncogene, a protein involved in cell growth. These...
20 KB (2,038 words) - 17:43, 25 August 2024
operator of Rotterdam, the Netherlands Røst Airport, Norway (IATA code) RET proto-oncogene, a gene on human chromosome 10 Resonance energy transfer, a mechanism...
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thyroid cancer cases are genetic in nature, caused by a mutation in the RET proto-oncogene. When MTC occurs by itself it is termed sporadic medullary thyroid...
19 KB (2,285 words) - 13:12, 25 August 2024
spermatogonia into primary spermatocytes, i.e. it is received by RET proto-oncogene (RET) and by forming gradient with SCF it divides the spermatogonia...
24 KB (2,770 words) - 15:39, 7 June 2024
Proto-oncogene tyrosine-protein kinase Src, also known as proto-oncogene c-Src, or simply c-Src (cellular Src; pronounced "sarc", as it is short for sarcoma)...
21 KB (2,648 words) - 12:12, 26 July 2024
Receptor tyrosine kinase (section RET receptor family)
"Characterization of RET proto-oncogene 3' splicing variants and polyadenylation sites: a novel C-terminus for RET". Oncogene. 11 (10): 2039–45. PMID 7478523...
28 KB (3,078 words) - 07:46, 3 June 2024
process is vandetanib, a tyrosine kinase inhibitor that targets the RET proto-oncogene, two subtypes of the vascular endothelial growth factor receptor,...
61 KB (5,480 words) - 02:32, 2 September 2024
nonpeptidergic nociceptors switch off the TrkA and begin expressing RET proto-oncogene, which is a transmembrane signaling component that allows the expression...
24 KB (2,854 words) - 23:06, 13 August 2024
pathway—the MAPK/ERK pathway. Chromosomal translocations involving the RET proto-oncogene (encoding a tyrosine kinase receptor that plays essential roles in...
35 KB (3,945 words) - 16:22, 29 December 2023
platelet-derived growth factor receptor (PDGFR) alpha, c-Kit, and the RET proto-oncogene. Some of these proteins play roles in cancerogenic signalling pathways...
11 KB (934 words) - 23:22, 24 August 2024
abilities t(10;(various))(q11;(various)) Papillary thyroid cancer RET proto-oncogene on chromosome 10 PTC (Papillary Thyroid Cancer) – Placeholder for...
19 KB (1,523 words) - 17:16, 1 August 2024
Moore JK, Papi L; et al. (Jun 1993). "Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A". Nature. 363 (6428): 458–60...
21 KB (2,231 words) - 12:09, 12 August 2024
from a variation in the RET proto-oncogene, and are specific for cells of neural crest origin. A database of MEN-implicated RET mutations is maintained...
10 KB (1,086 words) - 13:13, 25 August 2024
genes (Menin gene in MEN1), or involve gain of function mutations (RET proto-oncogene MEN 2a).[citation needed] Recently, it was demonstrated that liquidators...
22 KB (2,314 words) - 22:30, 13 August 2024
endoneurium-like fibrous stroma.[citation needed] Variations in the RET proto-oncogene cause MEN2B. In recent decades no case of MEN2B has been reported...
17 KB (1,957 words) - 13:26, 25 August 2024
Hepatocyte growth factor receptor (redirect from Proto-oncogene proteins c-met)
in the MET gene are associated with papillary renal carcinoma. MET proto-oncogene (GeneID: 4233) has a total length of 125,982 bp, and it is located in...
58 KB (6,927 words) - 03:33, 17 June 2024
Kyte-Doolittle-Hydropathy Plot for Human RET proto-oncogene. Plot was created using the ExPASy Protscale tool (http://web.expasy.org/protscale/)....
3 KB (264 words) - 05:26, 1 February 2022
proteins such as the GDNF family of ligand proteins encoded by the RET proto-oncogene gene, ASCL1 protein encoded by the ASCL1 gene, Dok-7 protein encoded...
36 KB (4,448 words) - 22:32, 17 January 2024
ROS1 (redirect from C-ros oncogene 1)
Proto-oncogene tyrosine-protein kinase ROS is an enzyme that in humans is encoded by the ROS1 gene. This proto-oncogene, highly expressed in a variety...
29 KB (3,681 words) - 23:18, 20 August 2024
KIT (gene) (redirect from Proto-oncogene proteins c-kit)
Proto-oncogene c-KIT is the gene encoding the receptor tyrosine kinase protein known as tyrosine-protein kinase KIT, CD117 (cluster of differentiation...
35 KB (4,117 words) - 00:12, 6 August 2024
phosphatase and tensin homolog (mutated in multiple advanced cancers 1) RET: ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1...
28 KB (1,967 words) - 02:02, 11 April 2024
tyrosine kinase enzymes: anaplastic lymphoma kinase (ALK) and the RET proto-oncogene. The active metabolite M4 has similar activity against ALK. Inhibition...
22 KB (1,787 words) - 05:10, 1 July 2024
domain of H4 (D10S170), a gene frequently rearranged with the ret proto-oncogene". Oncogene. 10 (9): 1781–7. PMID 7753554. Hillier LD, Lennon G, Becker...
8 KB (1,009 words) - 01:18, 11 October 2023
RET genes code for receptor tyrosine kinases, i.e. the epidermal growth factor receptor, platelet-derived growth factor receptor beta, and RET proto-oncogene...
16 KB (1,860 words) - 12:53, 13 May 2024
BRAF (gene) (redirect from V-raf murine sarcoma viral oncogene homolog B1)
called B-Raf. The gene is also referred to as proto-oncogene B-Raf and v-Raf murine sarcoma viral oncogene homolog B, while the protein is more formally...
48 KB (5,285 words) - 16:26, 21 August 2024
Platelet-derived growth factor (redirect from Proto-oncogene proteins c-sis)
31–46. doi:10.1016/0092-8674(92)90531-G. PMID 1623522. S2CID 11529297. Proto-Oncogene+Proteins+c-sis at the U.S. National Library of Medicine Medical Subject...
24 KB (2,877 words) - 10:08, 2 June 2024
F.; Goodfellow, Paul; Wells, Samuel A. (1993). "Mutations in the RET proto-oncogene are associated with MEN 2A and FMTC". Human Molecular Genetics. 2...
12 KB (1,024 words) - 18:49, 25 July 2024