E3 ubiquitin-protein ligase RNF8 is an enzyme that in humans is encoded by the RNF8 gene. RNF8 has activity both in immune system functions and in DNA...
18 KB (2,317 words) - 01:29, 3 December 2023
decondensation, but within 30 seconds of irradiation, RNF8 protein can be detected in association with γH2AX. RNF8 mediates extensive chromatin decondensation,...
53 KB (5,924 words) - 16:38, 18 July 2024
but within 30 seconds of ionizing radiation, RNF8 protein can be detected in association with γH2AX. RNF8 mediates extensive chromatin decondensation,...
22 KB (2,775 words) - 09:59, 27 March 2024
simultaneous accumulation of RNF8 protein and the DNA repair protein NBS1 which bind to MDC1 as MDC1 attaches to γH2AX. RNF8 mediates extensive chromatin...
50 KB (5,523 words) - 09:43, 3 December 2023
decondensation, but within 30 seconds of irradiation, RNF8 protein can be detected in association with γH2AX. RNF8 mediates extensive chromatin decondensation,...
128 KB (15,837 words) - 04:28, 8 July 2024
decondensation, but within 30 seconds of irradiation, RNF8 protein can be detected in association with γH2AX. RNF8 mediates extensive chromatin decondensation,...
106 KB (12,105 words) - 20:29, 9 March 2024
decondensation, but within 30 seconds of irradiation, RNF8 protein can be detected in association with γH2AX. RNF8 mediates extensive chromatin decondensation,...
79 KB (9,956 words) - 11:19, 14 March 2024
domain solution structure of the fha domain of human ubiquitin ligase protein rnf8 Identifiers Symbol FHA Pfam PF00498 Pfam clan CL0357 InterPro IPR000253 PROSITE...
3 KB (370 words) - 01:07, 18 June 2024
VCP is recruited to DNA lesions and cooperates with the ubiquitin ligase RNF8 to orchestrate assembly of signaling complexes for efficient DSB repair....
121 KB (13,635 words) - 05:09, 13 July 2024
the binding of RNF8, a RING finger ubiquitin ligase to the E2 ubiquitin-conjugating enzyme UBC13. This association is required for RNF8 mediated Lys-63...
27 KB (3,301 words) - 12:04, 3 July 2024
"Molecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylation". The Journal of Biological...
98 KB (11,068 words) - 18:25, 16 July 2024
the TQXF domain on MDC1 which allows it to recruit the E3 ubiquitin ligase RNF8, which will ubiquitinate the histones near the DSB which initiates further...
24 KB (3,123 words) - 21:25, 27 March 2024
HGNC:10068 Q99942 13841 RNF6 HGNC:10069 Q9Y252 13842 RNF7 HGNC:10070 Q9UBF6 13843 RNF8 HGNC:10071 O76064 13844 RNF10 HGNC:10055 Q8N5U6 13845 RNF11 HGNC:10056 Q9Y3C5...
282 KB (17 words) - 07:55, 20 June 2024
genes: PCDH10, DIA1 (formerly known as C3ORF58), NHE9, CNTN3, SCN7A, and RNF8. Several of these genes appeared to be targets of MEF2, one of the transcription...
113 KB (10,805 words) - 02:14, 8 July 2024
ubiquitylation, and double-strand DNA repair independent of ATM, MDC1, and RNF8". Mol. Cell. Biol. 33 (4): 845–57. doi:10.1128/MCB.00990-12. PMC 3571337...
8 KB (1,057 words) - 02:55, 21 July 2024
RFPL2, RFPL3, RFPL4B, RFWD2, RFWD3, RING1, RNF2, RNF4, RNF5, RNF6, RNF7, RNF8, RNF10, RNF11, RNF12, RNF13, RNF14, RNF19A, RNF20, RNF24, RNF25, RNF26, RNF32...
12 KB (1,259 words) - 02:55, 21 July 2024
scaRNAs and the enzyme telomerase. WRAP53β also targets the ubiquitin ligase RNF8 to DNA double-strand breaks(Figure 2). In addition to localizing factors...
16 KB (1,837 words) - 03:35, 2 June 2024
NCOA6, NFKBIB, NPAS2, NRIP1, NR4A1, NCOA2, NCOA3, POU2F1, PPARGC1A, PPAR-γ, RNF8, RAR-α, SHP, TADA3L, TBP, TRIM24, TR-β, and VDR. Retinoid X receptor GRCh38:...
25 KB (2,892 words) - 21:07, 15 November 2023
enzymes (E2s) mediate the ubiquitination of RING-finger proteins, ARA54 and RNF8". Eur. J. Biochem. 268 (9): 2725–32. doi:10.1046/j.1432-1327.2001.02169.x...
6 KB (752 words) - 06:02, 5 January 2024
enzymes (E2s) mediate the ubiquitination of RING-finger proteins, ARA54 and RNF8". Eur. J. Biochem. 268 (9): 2725–32. doi:10.1046/j.1432-1327.2001.02169.x...
8 KB (1,058 words) - 01:29, 3 December 2023
enzymes (E2s) mediate the ubiquitination of RING-finger proteins, ARA54 and RNF8". Eur. J. Biochem. 268 (9): 2725–32. doi:10.1046/j.1432-1327.2001.02169.x...
7 KB (910 words) - 22:21, 2 December 2023
production of the heterotrimer depends on p12 degradation by the E3 ligase RNF8, a protein involved in DSBs repair and possibly homologous recombination...
75 KB (7,977 words) - 01:03, 18 May 2024
enzymes (E2s) mediate the ubiquitination of RING-finger proteins, ARA54 and RNF8". Eur. J. Biochem. 268 (9): 2725–32. doi:10.1046/j.1432-1327.2001.02169.x...
6 KB (548 words) - 17:14, 13 January 2024