Reverse-transcriptase inhibitors (RTIs) are a class of antiretroviral drugs used to treat HIV infection or AIDS, and in some cases hepatitis B. RTIs inhibit...
25 KB (2,897 words) - 23:33, 1 December 2024
A reverse transcriptase (RT) is an enzyme used to convert RNA genome to DNA, a process termed reverse transcription. Reverse transcriptases are used by...
27 KB (3,047 words) - 16:08, 28 November 2024
reverse-transcriptase inhibitor (NNRTI), protease inhibitor (PI) or integrase inhibitors (also known as integrase nuclear strand transfer inhibitors or INSTIs)...
133 KB (15,784 words) - 05:42, 17 September 2024
inhibitor; emtricitabine, an HIV-1 nucleoside analog reverse transcriptase inhibitor; and tenofovir alafenamide, an HIV-1 nucleoside analog reverse transcriptase...
14 KB (1,200 words) - 12:24, 8 October 2024
Zidovudine (category Nucleoside analog reverse transcriptase inhibitors)
of the nucleoside analog reverse-transcriptase inhibitor (NRTI) class. It works by inhibiting the enzyme reverse transcriptase that HIV uses to make DNA...
48 KB (4,910 words) - 07:29, 30 November 2024
Lamivudine (category Nucleoside analog reverse transcriptase inhibitors)
food. Lamivudine is a nucleoside reverse transcriptase inhibitor and works by blocking the HIV reverse transcriptase and hepatitis B virus polymerase...
16 KB (1,566 words) - 08:15, 1 May 2024
abacavir (reverse transcriptase inhibitor), dolutegravir (integrase inhibitor) and lamivudine (nucleoside analog reverse transcriptase inhibitor). The medication...
14 KB (1,267 words) - 05:54, 6 August 2024
nucleotide reverse-transcriptase inhibitors (NRTIs and NtRTIs) began in the 1980s when the AIDS epidemic hit Western societies. NRTIs inhibit the reverse transcriptase...
33 KB (3,234 words) - 06:11, 2 November 2024
Non-nucleoside reverse-transcriptase inhibitors (NNRTIs) are antiretroviral drugs used in the treatment of human immunodeficiency virus (HIV). NNRTIs inhibit reverse...
37 KB (4,737 words) - 09:58, 27 March 2024
Efavirenz (category Non-nucleoside reverse transcriptase inhibitors)
It is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and works by blocking the function of reverse transcriptase. Efavirenz was approved for...
31 KB (2,825 words) - 01:51, 1 December 2024
nucleoside reverse transcriptase inhibitors along with a third ARV, either an integrase strand transfer inhibitor (INSTI), a non-nucleoside reverse transcriptase...
211 KB (21,194 words) - 15:30, 2 January 2025
of the nucleoside reverse transcriptase inhibitor (NRTI) class. They work by blocking the action of the enzyme, reverse transcriptase, that the virus requires...
13 KB (1,248 words) - 19:17, 17 March 2024
CYP3A4 (redirect from CYP3A4 inhibitor)
chlorphenamine; protease inhibitors: indinavir, ritonavir, saquinavir, nelfinavir; non-nucleoside reverse-transcriptase inhibitors (antiretroviral drugs):...
80 KB (7,794 words) - 00:31, 3 December 2024
Nevirapine (category Non-nucleoside reverse transcriptase inhibitors)
It is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and works by blocking the function of reverse transcriptase. Nevirapine was approved...
31 KB (3,044 words) - 05:45, 24 May 2024
and nuclease-free water in a PCR tube. Then, add an RNase inhibitor and reverse transcriptase to the PCR tube. Next, place the PCR tube into a thermal...
44 KB (5,656 words) - 23:37, 29 October 2024
is a non-nucleoside reverse transcriptase inhibitor (NNRTI) of HIV-1. Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) of HIV-1. Tenofovir...
13 KB (995 words) - 18:25, 21 March 2024
Rilpivirine (category Non-nucleoside reverse transcriptase inhibitors)
treatment of HIV/AIDS. It is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect...
19 KB (1,652 words) - 14:35, 6 August 2024
integrase strand transfer inhibitor (INSTI), and 300 mg lamivudine, a nucleoside analogue reverse transcriptase inhibitor (NRTI). It is taken by mouth...
9 KB (612 words) - 06:28, 29 May 2024
Atevirdine (category Non-nucleoside reverse transcriptase inhibitors)
Atevirdine is a non-nucleoside reverse transcriptase inhibitor that has been studied for the treatment of HIV. Preparation of the pyridylpiperazine moiety...
4 KB (267 words) - 22:39, 5 August 2024
Adefovir (category Reverse transcriptase inhibitors)
and Hepsera. It is an orally administered nucleotide analog reverse-transcriptase inhibitor (ntRTI). It can be formulated as the pivoxil prodrug adefovir...
6 KB (540 words) - 15:12, 20 November 2023
Zalcitabine (category Nucleoside analog reverse transcriptase inhibitors)
ddC), also called dideoxycytidine, is a nucleoside analog reverse-transcriptase inhibitor (NRTI) sold under the trade name Hivid. Zalcitabine was the...
11 KB (1,054 words) - 16:44, 29 September 2024
WHO Model List of Essential Medicines (section Nucleoside/nucleotide reverse transcriptase inhibitors)
is an alternative For use only in patients with HIV receiving protease inhibitors. For use only in combination with meropenem or imipenem/cilastatin. Terizidone...
67 KB (4,835 words) - 16:55, 29 December 2024
Telomerase reverse transcriptase (abbreviated to TERT, or hTERT in humans) is a catalytic subunit of the enzyme telomerase, which, together with the telomerase...
46 KB (5,304 words) - 20:19, 20 October 2024
reverse-transcriptase inhibitor and a non-nucleoside reverse-transcriptase inhibitor". The approval text describes it as a dual reverse transcriptase...
18 KB (2,078 words) - 20:39, 3 June 2024
Doravirine (category Non-nucleoside reverse transcriptase inhibitors)
Doravirine, sold under the brand name Pifeltro, is a non-nucleoside reverse transcriptase inhibitor medication developed by Merck & Co. for use in the treatment...
4 KB (199 words) - 08:43, 10 July 2024
Tenofovir disoproxil (category Nucleoside analog reverse transcriptase inhibitors)
during pregnancy and appears to be safe. It is a nucleotide reverse transcriptase inhibitor and works by decreasing the ability of the viruses to replicate...
26 KB (2,369 words) - 04:54, 19 August 2024
Retrovirus (redirect from Reverse transcribing viruses)
cell's cytoplasm, the virus uses its own reverse transcriptase enzyme to produce DNA from its RNA genome, the reverse of the usual pattern, thus retro (backward)...
41 KB (4,727 words) - 02:05, 8 September 2024
protease inhibitor) Darunavir (HIV protease inhibitor) Delavirdine (non-nucleoside reverse transcriptase inhibitor) Fosamprenavir (HIV protease inhibitor) Tipranavir...
4 KB (261 words) - 18:09, 4 November 2024
Tenofovir alafenamide (category Nucleoside analog reverse transcriptase inhibitors)
It is taken by mouth. Tenofovir alafenamide is a nucleotide reverse transcriptase inhibitor and is a prodrug of tenofovir. It was developed by Gilead Sciences...
29 KB (1,823 words) - 05:48, 26 July 2024
medication for the treatment of HIV/AIDS. It contains three reverse transcriptase inhibitors patented by GlaxoSmithKline and marketed by a joint venture...
8 KB (484 words) - 06:52, 5 November 2024