Somatostatin, also known as growth hormone-inhibiting hormone (GHIH) or by several other names, is a peptide hormone that regulates the endocrine system...
23 KB (2,532 words) - 08:06, 21 July 2024
Somatostatin receptors are receptors for the ligand somatostatin, a small neuropeptide associated with neural signaling, particularly in the post-synaptic...
3 KB (155 words) - 08:25, 29 January 2023
Acromegaly (section Somatostatin analogues)
surgery will be curative. If surgery is contraindicated or not curative, somatostatin analogues or GH receptor antagonists may be used. Radiation therapy may...
44 KB (4,525 words) - 19:04, 30 September 2024
Octreotide (category Somatostatin inhibitors)
name Sandostatin among others, is an octapeptide that mimics natural somatostatin pharmacologically, though it is a more potent inhibitor of growth hormone...
31 KB (2,731 words) - 22:04, 30 September 2024
Somatostatin receptor type 2 is a protein that in humans is encoded by the SSTR2 gene. The SSTR2 gene is located on chromosome 17 on the long arm in position...
32 KB (4,012 words) - 12:39, 29 August 2024
Somatostatin receptor antagonists (or somatostatin inhibitors) are a class of chemical compounds that work by imitating the structure of the neuropeptide...
37 KB (3,838 words) - 19:57, 27 May 2024
Delta cell (redirect from Somatostatin-secreting cells)
Delta cells (δ-cells or D cells) are somatostatin-producing cells. They can be found in the stomach, intestine and the pancreatic islets. Delta cells comprise...
7 KB (835 words) - 16:10, 2 May 2024
tumours express somatostatin receptors providing a unique target for imaging. Octreotide is a synthetic modification of somatostatin with a longer half-life...
87 KB (8,013 words) - 13:43, 25 July 2024
Somatostatin receptor antagonists (or somatostatin inhibitors) are a class of chemical compounds that work by imitating the structure of the neuropeptide...
35 KB (3,724 words) - 04:58, 27 April 2024
Octreotide scan (redirect from Somatostatin receptor scintigraphy)
localize sarcoidosis. It is also called somatostatin receptor scintigraphy (SRS). Octreotide, a drug similar to somatostatin, is radiolabeled with indium-111...
13 KB (871 words) - 05:51, 12 September 2024
by somatostatin (growth-hormone-inhibiting hormone). Somatostatin is released from neurosecretory nerve terminals of periventricular somatostatin neurons...
12 KB (1,281 words) - 15:01, 22 July 2024
(GHRH or somatocrinin) and growth hormone-inhibiting hormone (GHIH or somatostatin) into the hypophyseal portal venous blood surrounding the pituitary....
57 KB (6,664 words) - 15:04, 22 July 2024
The somatostatin family is a protein family with somatostatin as titular member, a hormone which inhibits the release of the pituitary somatotropin (growth...
1 KB (116 words) - 07:33, 30 January 2021
edu/hbooks/pathphys/endocrine/otherendo/somatostatin.html Colorado State University - Biomedical Hypertextbooks - Somatostatin Nosek, Thomas M. "Section 5/5ch4/s5ch4_17"...
27 KB (343 words) - 01:10, 26 September 2024
Somatostatin receptor type 5 is a protein that in humans is encoded by the SSTR5 gene. Somatostatin acts at many sites to inhibit the release of many...
8 KB (1,007 words) - 06:28, 10 March 2024
releases gastrin releasing peptide onto G cells. Finally, it also inhibits somatostatin release from D cells. The gastric phase: About sixty percent of the total...
15 KB (1,772 words) - 22:35, 9 May 2024
Somatostatin receptor type 4 is a protein that in humans is encoded by the SSTR4 gene. Somatostatin acts at many sites to inhibit the release of many...
9 KB (1,072 words) - 06:28, 10 March 2024
score is used to grade the uptake intensity of neuroendocrine tumors on somatostatin receptor imaging such as octreotide scan.[further explanation needed]...
2 KB (86 words) - 00:54, 3 July 2022
cerebral cortex, and which has a strong structural similarity to somatostatin. Unlike somatostatin, when infused into the brain, it enhances slow-wave sleep...
7 KB (868 words) - 09:16, 5 January 2024
Somatostatin receptor type 1 is a protein that in humans is encoded by the SSTR1 gene. Somatostatin acts at many sites to inhibit the release of many...
10 KB (1,215 words) - 17:02, 16 February 2024
Shekel Somatostatin receptor type 3 is a protein that in humans is encoded by the SSTR3 gene. Somatostatin acts at many sites to inhibit the release of...
10 KB (1,191 words) - 03:58, 29 January 2023
regulate blood sugar levels, secreting the hormones insulin, glucagon, somatostatin and pancreatic polypeptide. As a part of the digestive system, it functions...
51 KB (5,703 words) - 20:00, 25 September 2024
used in the treatment of cancers which express somatostatin receptors. It is a radiolabeled somatostatin analog. Alternatives to 177Lu-dotatate include...
19 KB (1,408 words) - 09:37, 9 May 2024
Vasopressin receptor antagonist (section Somatostatin)
Nelivaptan V2 selective (V2RA) Lixivaptan Mozavaptan Satavaptan Tolvaptan Somatostatin is a competitive inhibitor. Demeclocycline, a tetracycline antibiotic...
10 KB (1,059 words) - 05:14, 3 June 2024
weeks into development, the pancreas starts producing insulin, glucagon, somatostatin, and pancreatic polypeptide. During the early stages of fetal development...
39 KB (4,603 words) - 22:38, 3 October 2024
Melanocyte-stimulating hormone (MSH) Oxytocin Parathyroid hormone (PTH) Prolactin Renin Somatostatin Thyroid-stimulating hormone (TSH) Thyrotropin-releasing hormone (TRH)...
5 KB (547 words) - 00:01, 22 August 2024
acting directly on anterior pituitary and by stimulating the secretion of somatostatin from the hypothalamus. Somatomedins are a group of proteins that promote...
2 KB (241 words) - 04:50, 18 August 2024
a form of peptide receptor radionuclide therapy (PRRT) which targets somatostatin receptors (SSR). In that form of application it is a form of targeted...
13 KB (1,205 words) - 22:35, 3 December 2023
syndrome largely arise in the gut. CT and MRI that utilize radioactive somatostatin analogues such as indium-111 pentetreotide are used to localize the tumor...
17 KB (1,812 words) - 00:11, 31 August 2024
can be achieved, as in PRRT. The current generation of PRRT targets somatostatin receptors, with a range of analogue materials such as octreotide and...
28 KB (2,914 words) - 02:17, 16 July 2024