• The genome and proteins of HIV (human immunodeficiency virus) have been the subject of extensive research since the discovery of the virus in 1983. "In...
    33 KB (3,936 words) - 19:07, 2 September 2024
  • Thumbnail for HIV
    Two RNA genomes are encapsidated in each HIV-1 particle (see Structure and genome of HIV). Upon infection and replication catalyzed by reverse transcriptase...
    123 KB (14,115 words) - 23:45, 17 November 2024
  • Thumbnail for Virus
    the viral genome and host genome; the lipid membrane itself and any carbohydrates present originate entirely from the host. Influenza virus, HIV (which causes...
    155 KB (18,247 words) - 21:39, 28 October 2024
  • Thumbnail for Pathophysiology of HIV/AIDS
    cytopathy. Structure and genome of HIV HIV replication cycle HIV tropism Doitsh, G; Greene, WC (2016). "Dissecting How CD4 T Cells Are Lost During HIV Infection"...
    14 KB (1,841 words) - 11:04, 2 July 2024
  • Thumbnail for Reverse transcriptase
    used to convert RNA genome to DNA, a process termed reverse transcription. Reverse transcriptases are used by viruses such as HIV and hepatitis B to replicate...
    27 KB (3,043 words) - 03:16, 30 June 2024
  • Thumbnail for Integrase
    Integrase (redirect from Hiv integrase)
    domains and 2-domain constructs of integrases from HIV-1, HIV-2, SIV, and Rous Sarcoma Virus (RSV) have been reported, with the first structures determined...
    12 KB (1,288 words) - 02:08, 1 June 2024
  • Thumbnail for Simian immunodeficiency virus
    in microbial abundance. The pattern of natural selection in the monkey genome in genes involved in HIV responses and those regulated in response to experimental...
    35 KB (3,270 words) - 06:57, 3 September 2024
  • Thumbnail for Long terminal repeat
    element of many retroviruses. DIS is characterized by a conserved stem and palindromic loop that forms a kissing-loop complex between HIV-1 RNA genomes to...
    11 KB (1,378 words) - 11:06, 3 December 2023
  • Thumbnail for P24 capsid protein
    P24 capsid protein (category HIV/AIDS)
    gene. The structure of HIV capsid was determined by X-ray crystallography and cryo-electron microscopy. The p24 capsid protein consists of two domains:...
    13 KB (1,457 words) - 10:47, 13 November 2024
  • Thumbnail for Subtypes of HIV
    subtypes of HIV include two main subtypes, known as HIV type 1 (HIV-1) and HIV type 2 (HIV-2). These subtypes have distinct genetic differences and are associated...
    34 KB (3,864 words) - 22:49, 7 November 2024
  • Thumbnail for Adenoviridae
    double-stranded DNA genome. Their name derives from their initial isolation from human adenoids in 1953. They have a broad range of vertebrate hosts; in...
    49 KB (5,559 words) - 18:51, 11 October 2024
  • Thumbnail for Retrovirus
    Retrovirus (category Modification of genetic information)
    retrovirus is a type of virus that inserts a DNA copy of its RNA genome into the DNA of a host cell that it invades, thus changing the genome of that cell. After...
    41 KB (4,727 words) - 02:05, 8 September 2024
  • Thumbnail for HIV integration
    replication cycle of HIV-1 and other retroviruses is the integration of this viral DNA into the host DNA. The RNA genome of progeny virions and the template...
    16 KB (2,137 words) - 08:40, 9 August 2023
  • Thumbnail for DNA
    DNA (redirect from Structure of DNA)
    of the DNA structure DNA from the Beginning Another DNA Learning Center site on DNA, genes, and heredity from Mendel to the human genome project. The...
    166 KB (17,843 words) - 13:16, 19 September 2024
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    J, Hendrickson WA (June 1998). "Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody". Nature...
    22 KB (2,581 words) - 20:03, 21 June 2024
  • Thumbnail for Genome editing
    Genome editing, or genome engineering, or gene editing, is a type of genetic engineering in which DNA is inserted, deleted, modified or replaced in the...
    78 KB (9,361 words) - 01:20, 25 September 2024
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    S2CID 4206886. "Virology – Human Immunodeficiency Virus And Aids, Structure: The Genome And Proteins of HIV". Pathmicro.med.sc.edu. 1 July 2010. Retrieved 27...
    80 KB (7,349 words) - 03:33, 21 November 2024
  • Thumbnail for Envelope glycoprotein GP120
    exposed on the surface of the HIV envelope. It was discovered by Professors Tun-Hou Lee and Myron "Max" Essex of the Harvard School of Public Health in 1984...
    21 KB (2,547 words) - 00:52, 4 December 2023
  • The LTR of HIV is positively auto regulated by the Tat (transcription activator) protein, which is found towards the 3' end of the HIV genome. Without...
    22 KB (2,573 words) - 06:14, 26 June 2024
  • Thumbnail for HIV gag stem loop 3 (GSL3)
    RNA packaging and is located the 5’ untranslated region of the unspliced HIV-1 genome. GSL3 is known to direct specific packaging of HIV-1 genomic RNA...
    5 KB (548 words) - 07:51, 17 May 2022
  • management of HIV/AIDS normally includes the use of multiple antiretroviral drugs as a strategy to control HIV infection. There are several classes of antiretroviral...
    133 KB (15,784 words) - 05:42, 17 September 2024
  • The HIV-1 Rev response element (RRE) is a highly structured, ~350 nucleotide RNA segment present in the Env coding region of unspliced and partially spliced...
    19 KB (2,218 words) - 14:35, 3 July 2024
  • Thumbnail for Retroviral psi packaging element
    cis-acting RNA element identified in the genomes of the retroviruses Human immunodeficiency virus (HIV) and Simian immunodeficiency virus (SIV). It is...
    11 KB (1,180 words) - 00:09, 31 December 2023
  • Thumbnail for HIV/AIDS research
    fundamental research about the nature of HIV as an infectious agent and AIDS as the disease caused by HIV. A body of scientific evidence has shown that men...
    42 KB (5,219 words) - 05:16, 8 October 2024
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    living with HIV to lead long and healthy lives. An HIV-positive person on treatment can expect to live a normal life, and die with the virus, not of it. Effective...
    211 KB (21,173 words) - 15:29, 13 November 2024
  • Thumbnail for VP40
    VP40 (section Structure)
    and the C-terminal membrane-binding domain, connected by a flexible linker. Both the N- and C-terminal domains fold into beta sandwich structures of similar...
    7 KB (732 words) - 14:30, 24 August 2024
  • Thumbnail for Ribonuclease H
    as HIV and are required for viral replication. In eukaryotes, ribonuclease H1 is involved in DNA replication of the mitochondrial genome. Both H1 and H2...
    54 KB (5,823 words) - 20:53, 22 July 2024
  • Thumbnail for HIV ribosomal frameshift signal
    maximizing the storage capacity of their genome. Thus, many viruses (including HIV-1) are categorized as having a polycistronic genome, meaning they employ multiple...
    10 KB (1,273 words) - 17:56, 13 March 2023
  • Thumbnail for History of HIV/AIDS
    are two types of HIV: HIV-1 and HIV-2. HIV-1 is more virulent, more easily transmitted, and it is the cause of the vast majority of HIV infections globally...
    118 KB (14,015 words) - 13:25, 20 November 2024
  • convention, the HIV genome is numbered according to HIV-1 group M subtype B reference strain HXB2. After a virus enters a target cell, the viral genome is integrated...
    13 KB (1,572 words) - 07:58, 9 August 2023