Succinate dehydrogenase (SDH) or succinate-coenzyme Q reductase (SQR) or respiratory complex II is an enzyme complex, found in many bacterial cells and...
27 KB (2,942 words) - 05:16, 11 November 2024
Succinate dehydrogenase complex subunit C, also known as succinate dehydrogenase cytochrome b560 subunit, mitochondrial, is a protein that in humans is...
17 KB (2,178 words) - 06:41, 3 June 2024
Succinic acid (redirect from Succinate)
anion, succinate, which has multiple biological roles as a metabolic intermediate being converted into fumarate by the enzyme succinate dehydrogenase in complex...
47 KB (4,543 words) - 03:44, 25 October 2024
intermembrane space per two electrons from NADH. In Complex II (succinate dehydrogenase or succinate-CoQ reductase; EC 1.3.5.1) additional electrons are delivered...
33 KB (4,063 words) - 21:34, 28 October 2024
it is reduced to ubiquinol (QH2). Succinate-Q oxidoreductase, also known as complex II or succinate dehydrogenase, is a second entry point to the electron...
88 KB (9,674 words) - 18:37, 5 November 2024
Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial (CybS), also known as succinate dehydrogenase complex subunit D (SDHD),...
21 KB (2,718 words) - 06:22, 3 June 2024
addition, electrons from the succinate oxidation step are transferred first to the FAD cofactor of succinate dehydrogenase, reducing it to FADH2, and eventually...
56 KB (6,064 words) - 00:44, 9 November 2024
Fumarate reductase (quinol) (redirect from Succinate:menaquinone oxidoreductase)
catalyzed by the related complex II of the respiratory chain (succinate dehydrogenase (SQR)). To date, a number of QFR enzymes have been crystalized...
17 KB (1,863 words) - 19:38, 16 October 2024
two atoms that the hydrogens were taken from, as in the case of succinate dehydrogenase. The two hydrogens have been transferred to the carrier or the...
19 KB (2,153 words) - 00:55, 2 March 2024
known: components of the succinate dehydrogenase complex, α-ketoglutarate dehydrogenase, and a component of the pyruvate dehydrogenase complex. FAD can exist...
39 KB (4,310 words) - 14:35, 24 September 2024
Succinate dehydrogenase complex, subunit A, flavoprotein variant is a protein that in humans is encoded by the SDHA gene. This gene encodes a major catalytic...
19 KB (2,202 words) - 14:09, 12 August 2024
Itaconic acid (section Inhibit succinate dehydrogenase)
Succinate dehydrogenase (i.e., SDH) is an enzyme complex of six proteins in the mitochondrial tricarboxylic acid cycle that metabolizes succinate to...
95 KB (11,779 words) - 02:34, 19 August 2024
compound is an biphenyl amide derived inhibitor of succinate dehydrogenase. Inhibition of succinate dehydrogenase, the complex II in the mitochondrial respiration...
10 KB (858 words) - 19:56, 7 September 2024
Reactions include oxidative metabolism (cytochrome c oxidase, succinate dehydrogenase), xenobiotic detoxification via cytochrome P450 pathways (including...
42 KB (4,371 words) - 06:57, 29 September 2024
SDHB (section Succinate accumulation in the cytosol)
SDHB gene. The succinate dehydrogenase (also called SDH or Complex II) protein complex catalyzes the oxidation of succinate (succinate + ubiquinone =>...
24 KB (2,957 words) - 07:03, 3 June 2024
NET (Neuroendocrine Tumor); CNS (Central Nervous System) SDHx (Succinate Dehydrogenase Subunit x) MAX (MYC Associated Factor X); TMEM127 (Transmembrane...
151 KB (16,268 words) - 03:01, 14 October 2024
is the classic example of a competitive inhibitor of the enzyme succinate dehydrogenase (complex II), in the respiratory electron transport chain. It binds...
20 KB (1,985 words) - 02:27, 6 September 2024
combines a heterocyclic acid with aniline to give an inhibitor of succinate dehydrogenase (SDHI). The first synthesis of carboxin was disclosed in patents...
10 KB (917 words) - 06:10, 24 August 2023
In enzymology, a succinate-semialdehyde dehydrogenase (SSADH) (EC 1.2.1.24) is an enzyme that catalyzes the chemical reaction succinate semialdehyde + NAD+...
3 KB (263 words) - 15:54, 26 August 2023
inhibitor of succinate dehydrogenase, an enzyme that inhibits cellular respiration in almost all living organisms. Inhibition of succinate dehydrogenase, the...
16 KB (1,368 words) - 22:31, 4 November 2024
MELAS syndrome (section NADH dehydrogenase)
(MT-ND1, MT-ND5) affected in MELAS encode proteins that are part of NADH dehydrogenase (also called complex I) in mitochondria, that helps convert oxygen and...
17 KB (1,797 words) - 22:06, 11 October 2024
L-malate, catalyzed by malate dehydrogenase, in the citric acid cycle. Malate is also oxidized by succinate dehydrogenase in a slow reaction with the initial...
12 KB (1,159 words) - 14:05, 16 November 2024
Succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79, succinic semialdehyde dehydrogenase (NADP+), succinyl semialdehyde dehydrogenase (NADP+), succinate...
2 KB (183 words) - 15:55, 26 August 2023
Succinate dehydrogenase complex assembly factor 2, formerly known as SDH5 and also known as SDH assembly factor 2 or SDHAF2 is a protein that in humans...
10 KB (1,258 words) - 06:26, 14 March 2024
Oncometabolism (section Succinate dehydrogenase)
cancer cells. Several mechanisms have been linked to D-2-hydroxyglutarate, succinate, and fumarate with the inhibition of α-KG–dependent dioxygenases, this...
32 KB (3,420 words) - 22:45, 1 September 2023
of commercial crops. It stunts fungus growth by inhibiting the succinate dehydrogenase (SQR) enzyme. Application of fluxapyroxad helps prevent many wilts...
13 KB (1,081 words) - 09:15, 20 September 2024
bupirimate metalaxyl carbendazim pencycuron Some fungicides target succinate dehydrogenase, a metabolically central enzyme. Fungi of the class Basidiomycetes...
14 KB (1,533 words) - 20:36, 13 October 2024
Alternaria, Sclerotinia, and Monilinia. It is an inhibitor of succinate dehydrogenase (SDHI fungicide). Developed and produced by Bayer, it was approved...
3 KB (184 words) - 04:53, 28 August 2023
combines a heterocyclic acid with aniline to give an inhibitor of succinate dehydrogenase (SDHI). Oxyxarboxin was first made by the oxidation of carboxin...
6 KB (511 words) - 19:18, 19 August 2023
are located in the mitochondrial matrix, with the exception of succinate dehydrogenase, which is bound to the inner mitochondrial membrane as part of...
167 KB (18,357 words) - 17:01, 19 November 2024