(tax-responsive enhancer element B67), also known as ATF4, is a protein that in humans is encoded by the ATF4 gene. This gene encodes a transcription factor...

complex called translation initiation factor 2 (eIF2), resulting in the gene ATF4 being turned on, which will further affect gene expression. eIF2 consists...

factors before it can carry out translation of the main protein. For example, ATF4 regulation is performed by two uORFs further upstream, named uORF1 and uORF2...

spilanthol inhibits the activation of several transcription factors (NFκB, ATF4, FOXO1, IRF1, ETS1, and AP-1) which may explain the effect of spilanthol...

genes encode CREB or CREB-like proteins: CREB1 (CREB1) CREB2 renamed ATF4 (ATF4) CREB3 (CREB3) CREB5 (CREB5) CREB3L1 (CREB3L1) CREB3L2 (CREB3L2) CREB3L3...

namely Alzheimer's disease, Parkinson's disease, and Huntington's disease. ATF4 and ATF5 are members of the leucine zipper activating transcription factor...

transcription factors, specifically ATF4, can influence how readily a neuron undergoes cell death. The presence of ATF4 promotes resistance in cells against...

amino acid, and results in an increase in activating transcription factor ATF4, which in turn affects many processes by sundry pathways to limit or increase...

they have in maintaining homeostasis. Some of these ATFs, such as ATF3, ATF4, and ATF6 are known to play a role in stress responses. Another example of...

complex relay of signals in the osteoblasts culminating in FoxO1/ Creb and ATF4 dependent transcriptional events. Following the 2008 findings that gut serotonin...

ENSG00000162772 bZIP Known motif – High-throughput in vitro [44] RTGACGTCAY ATF4 ENSG00000128272 bZIP Known motif – High-throughput in vitro [45] RKATGACGTCATMY...

reducing weakness and atrophy in aged skeletal muscle by interaction with the ATF4 (a critical mediator of age-related muscle weakness and atrophy). Dietary...

2 (PERK-eIF2α-ATF4 -CHOP-BCL2 pathway) HIV (XBP-1-CHOP-Caspase 3/9 pathway) Infectious bronchitis virus (PERK-eIF2α-ATF4/PKR-eIF2α-ATF4 pathway) M. tuberculosis...

SLC25A17 MCHR1 MKL1 SGSM3 ADSL TNRC6B FAM83F GRAP2 ENTHD1 CACNA1I RPS19BP1 ATF4 SMCR7L MGAT3 TAB1 SNORD43 RPL3 PDGFB CBX7 APOBEC3H APOBEC3F APOBEC3D APOBEC3C...

HGNC:783 P18846 1183 ATF2 HGNC:784 P15336 1184 ATF3 HGNC:785 P18847 1185 ATF4 HGNC:786 P18848 1186 ATF5 HGNC:790 Q9Y2D1 1187 ATF6 HGNC:791 P18850 1188...

1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation". Hum. Mol...

ASCC2: encoding protein activating signal cointegrator 1 complex subunit 2 ATF4 (22q13) encoding protein cyclic AMP-dependent transcription factor ATF-4...

regulatory element-I (PRE-I) enhancer elements. C/EBPγ forms heterodimer with ATF4 for transcriptional activation of target genes in autophagy specifically...

than 12000 human and mouse RNA-seq datasets. ATF1 NM_005171 ATF2 NM_001880 ATF4 Activating transcription factor 4 NM_001675 ATF6 NM_007348 ATF7 NM_001206682...

homologous protein), is upregulated downstream of the bZIP transcription factor ATF4 (activating transcription factor 4) and uniquely responsive to ER stress...

eIF2alpha phosphorylation determine cellular antioxidant status by regulating ATF4 and xCT expression". The Journal of Biological Chemistry. 284 (2). The American...

co-repressor complex. It has been also shown to interact with and inhibit the ATF4/CREB2 transcription factor that interacts with the basic transcription machinery...

promoter region of PCK2 contains two putative ATF/CRE sequences which bind ATF4. As a PCK, PCK2 catalyzes the GTP-driven conversion of OAA to PEP as a rate-limiting...

Zinc finger protein 521 (ZFP521) and activating transcription factor 4 (ATF4) are cofactors of Runx2. Binding of the transcriptional coregulator, WWTR1...

domains are zinc fingers. Human and animal proteins: ARNTL (BMAL1) ATF1 ATF4 (CREB2) BRCA1 CREB Cubitus interruptus (in D. melanogaster) ELK4 (SAP1) FOXO3...

Ddx3 Dhx9   DNA2 helicase E1A E2F Elk1 ER Ets1 Fen1 Foxo1 Gal4 GATA1 GR hATF4 HNF-1 Hif-1α Ku70   MDM2 MLL MyoD NF-κB p53 p73 Parp1 pCREB pCAF PCNA Pit1...

mays) kernels NFE2L2 or Nrf2 Bzip Maf transcription factors ATF1; ATF2; ATF4; ATF5; ATF6; ATF7; BACH1; BACH2; BATF; BATF2; CEBPA; CEBPB; CEBPD; CEBPE;...

yet known, but a basic zipper transcription factor called ATF4 is a possible candidate. ATF4 is related to GCN4. GCN2 also regulates the cell cycle by...

E. (2012) Brain-specific disruption of the eIF2a kinase PERK decreases ATF4 expression and impairs behavioral flexibility. Cell Rep. 1: 676–688. Hou...

a gene playing a role in ER stress-induced cell death, being a target of ATF4 that plays a role in ER-mediated cell death via promoting protein dephosphorylation...