Acetyl-L-carnitine, ALCAR or ALC, is an acetylated form of L-carnitine. It is naturally produced by the human body, and it is available as a dietary supplement...

synthesize enough L-carnitine in vivo. Carnitine exists as one of two stereoisomers: the two enantiomers d-carnitine (S-(+)-) and l-carnitine (R-(−)-). Both...

Ames, B. N. (2004). "Comparison of the effects of L-carnitine and acetyl-L-carnitine on carnitine levels, ambulatory activity, and oxidative stress biomarkers...

B, Lee FS, Young SP, Kautz MM, Albright A, et al. (August 2018). "Acetyl-l-carnitine deficiency in patients with major depressive disorder". Proceedings...

Administration of acetyl-L-carnitine was shown to improve these symptoms in mice. A subsequent human trial found that people with narcolepsy given L-carnitine spent...

to carnitine, generating CoA and an acyl-carnitine. (EC 2.3.1.137) Specifically, CROT catalyzes the chemical reaction: octanoyl-CoA + L-carnitine ⇌ {\displaystyle...

in prokaryotes and in the mitochondria in eukaryotes to generate acetyl-CoA. Acetyl-CoA enters the citric acid cycle, generating NADH and FADH2, which...

Citicoline, Huperzine A, Phosphatidylserine, Bacopa monnieri, Acetyl-L-carnitine, Uridine monophosphate, L-theanine, Rhodiola rosea, and Pycnogenol which are all...

Administration of acetyl-L-carnitine was shown to improve these symptoms in mice. A subsequent human trial found that narcolepsy patients given L-carnitine spent...

brain tissue of rats. Other possible treatments: Centrophenoxine Acetyl-L-carnitine Ginkgo biloba Dimethylethanolamine Curcumin Wet macular degeneration...

consuming diets that were not supplemented. L-carnitine is an amino acid and precursor of acetyl-L-carnitine which is a mitochondrial cofactor. It acts...

catalyzes the chemical reaction acetyl-CoA + carnitine ⇌ {\displaystyle \rightleftharpoons } CoA + acetylcarnitine where the acetyl group displaces the hydrogen...

relieve chronic pain, with some of the most studied supplements being: acetyl-L-carnitine, alpha-lipoic acid, and vitamin E. Vitamin E is perhaps the most studied...

Igisu H (July 1993). "Comparison of the effects of L-carnitine, D-carnitine and acetyl-L-carnitine on the neurotoxicity of ammonia". Biochemical Pharmacology...

specifically bipolar disorder, it is hypothesized that N-acetyl-cysteine (NAC), acetyl-L-carnitine (ALCAR), S-adenosylmethionine (SAMe), coenzyme Q10 (CoQ10)...

FSH, HCG, testosterone, Vitamin E, Vitamin C, anti-oxidants, carnitine, acetyl-L-carnitine, zinc, high-protein diets. In a number of pilot studies some...

pathways in cortical neurons to trigger protection by cotreatment of acetyl-L-carnitine and α-lipoic acid against HNE-mediated oxidative stress and neurotoxicity:...

Around 40% of dietary L-leucine is converted to acetyl-CoA, which is subsequently used in the synthesis of other compounds. The vast majority of L-leucine metabolism...

undisclosed amounts of vinpocetine in combination with huperzine A and acetyl-l-carnitine. In 2012, manufacturer Brain Research Labs (BRL) agreed to pay $500...

Carnitine palmitoyltransferase II deficiency, sometimes shortened to CPT-II or CPT2, is an autosomal recessively inherited genetic metabolic disorder...

mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid". Proceedings of the National Academy...

bipolar disorder, then it has been hypothesized that N-acetyl-cysteine (NAC), acetyl-L-carnitine (ALCAR), S-adenosylmethionine (SAMe), coenzyme Q10 (CoQ10)...

Carnitine palmitoyltransferase I (CPT1) also known as carnitine acyltransferase I, CPTI, CAT1, CoA:carnitine acyl transferase (CCAT), or palmitoylCoA transferase...

nervous system stimulant Acetylcarnitine, also known as Acetyl-L-carnitine – Form of L-carnitine (ALCAR) Meclofenoxate, also known as Centrophenoxine –...

six-month trial on 96 aged subjects with CFS symptoms administering acetyl L-carnitine was reported. By the end of the treatment, significant differences...

Hasegawa, Kyoko; Ando, Susumu (April 2004). "Acetyl-L-carnitine supplementation restores decreased tissue carnitine levels and impaired lipid metabolism in...

Acetyl-CoA carboxylase (ACC) is a biotin-dependent enzyme (EC 6.4.1.2) that catalyzes the irreversible carboxylation of acetyl-CoA to produce malonyl-CoA...

primary carnitine deficiency (SPCD) is an inborn error of fatty acid transport caused by a defect in the transporter responsible for moving carnitine across...

"Mitochondrial decay in aging. Reversal through supplementation of acetyl-L-carnitine and N-tert-butyl-alpha-phenyl-nitrone". Annals of the New York Academy...

randomized trials (RCTs) and guided by expert clinical experience. Acetyl-L-carnitine All-trans retinoic acid Amifostine Amitriptyline Calcium magnesium...