Actinin is a microfilament protein. The functional protein is an anti-parallel dimer, which cross-links the thin filaments in adjacent sarcomeres, and...
13 KB (1,649 words) - 05:05, 3 June 2024
Alpha-actinin-3, also known as alpha-actinin skeletal muscle isoform 3 or F-actin cross-linking protein, is a protein that in humans is encoded by the...
13 KB (1,581 words) - 14:02, 19 January 2024
Alpha-actinin-1 is a protein that in humans is encoded by the ACTN1 gene. Alpha actinins belong to the spectrin gene superfamily which represents a diverse...
12 KB (1,374 words) - 04:19, 8 March 2024
Alpha-actinin-2 is a protein which in humans is encoded by the ACTN2 gene. This gene encodes an alpha-actinin isoform that is expressed in both skeletal...
21 KB (2,601 words) - 17:21, 3 December 2023
Alpha-actinin-4 is a protein that in humans is encoded by the ACTN4 gene. Alpha actinins belong to the spectrin gene superfamily which represents a diverse...
12 KB (1,455 words) - 04:22, 8 March 2024
Gene doping (section Alpha-actinin-3)
growth factor, fibroblast growth factor, endorphin, enkephalin and alpha-actinin-3. The risks of gene doping would be similar to those of gene therapy:...
32 KB (3,911 words) - 03:05, 15 September 2024
structures are microfilaments of actin and actin-binding proteins, including α-actinin, fimbrin, and filamin are present in submembranous cortical layers and...
61 KB (6,102 words) - 11:22, 19 October 2024
Z-discs in striated muscle sarcomeres. Dense bodies are rich in alpha-actinin (α-actinin), and also attach intermediate filaments (consisting largely of vimentin...
37 KB (4,736 words) - 23:58, 3 October 2024
occludin, claudins, tight junction protein ZO-1, cadherins, catenins and actinin, which are directed by intracellular signal chains, in particular in connection...
30 KB (3,283 words) - 16:40, 26 August 2024
monomers, or polymers, or both. Many actin-binding proteins, including α-actinin, β-spectrin, dystrophin, utrophin and fimbrin, do this through the actin-binding...
10 KB (886 words) - 06:35, 18 March 2024
studies.[citation needed] Tight junction Pardo, JV, Craig, SW (1979). "alpha-Actinin localization in the junctional complex of intestinal epithelial cells"...
5 KB (505 words) - 05:55, 18 April 2024
Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors Cofilin 1 2 Destrin...
39 KB (3,017 words) - 13:44, 1 September 2024
channel activities that are substantially augmented by alpha-actinin. The TRPP3-alpha-actinin association was documented by co-immunoprecipitation using...
11 KB (1,385 words) - 04:58, 3 September 2023
intercalated discs. ALP functions to enhance the crosslinking of actin by alpha-actinin-2 and also appears to be essential for right ventricular chamber formation...
12 KB (1,442 words) - 01:33, 10 March 2024
encoded by the PDLIM1 gene. PDLIM1 has been shown to interact with: Actinin alpha 4, Actinin, alpha 1, Estrogen receptor alpha, and RNF12. GRCh38: Ensembl release...
8 KB (1,069 words) - 11:40, 17 October 2022
molecules are cross-linked in the Z-disc via the Z-line protein alpha-actinin. The M-band proteins myomesin as well as C-protein crosslink the thick...
12 KB (1,553 words) - 02:34, 3 September 2024
The N-terminal (the Z-disc end) contains a "Z repeat" that recognizes Actinin alpha 2. The elasticity of the PEVK region has both entropic and enthalpic...
45 KB (4,680 words) - 20:37, 25 October 2024
Actin-Related Protein-2/3 (or Arp2/3) complex Filament cross-linkers (e.g., α-actinin, fascin, and fimbrin) Actin monomer-binding proteins profilin and thymosin...
21 KB (2,785 words) - 17:16, 15 June 2024
Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors Cofilin 1 2 Destrin...
30 KB (3,168 words) - 14:29, 25 April 2024
transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin...
5 KB (682 words) - 23:10, 2 October 2024
ECM components, and intracellularly to microfilament-binding proteins α-actinin and talin to link the cytoskeleton with the outside. Integrins also serve...
25 KB (2,724 words) - 18:06, 10 August 2024
cell bodies and processes at both ends containing actin, myosin and actinin, giving mesangial cells contractile properties. The anchoring filaments...
14 KB (1,601 words) - 02:15, 3 December 2023
protein form of dendrin. Along with two other proteins, MAGI/S-SCAM and α-actinin, dendrin is linked to synaptic plasticity and memory formation in the brain...
15 KB (2,091 words) - 13:39, 22 September 2024
myosin I (NMMII), and also contain various crosslinking proteins, such as α-actinin, to form a highly regulated actomyosin structure within non-muscle cells...
24 KB (3,025 words) - 13:01, 3 October 2024
Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors Cofilin 1 2 Destrin...
64 KB (7,838 words) - 19:01, 10 September 2024
Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors Cofilin 1 2 Destrin...
45 KB (5,122 words) - 19:11, 1 November 2024
Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors Cofilin 1 2 Destrin...
32 KB (3,393 words) - 05:32, 15 June 2024
Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors Cofilin 1 2 Destrin...
30 KB (3,653 words) - 03:24, 22 July 2024
Tropomodulin 1 2 3 4 Troponin T 1 2 3 C 1 2 I 1 2 3 Tropomyosin 1 2 3 4 Actinin 1 2 3 4 Arp2/3 complex actin depolymerizing factors Cofilin 1 2 Destrin...
6 KB (631 words) - 20:38, 19 April 2024
signaling proteins (adhesion kinase (FAK), talin, vinculin, paxillin, α-actinin, GTPases etc.) which cause changes in cell shape and actomyosin contractility...
36 KB (4,084 words) - 22:32, 26 September 2024