(thrombin) and factor Xa. Antithrombin is also termed antithrombin III (AT III). The designations antithrombin I through to antithrombin IV originate in early...
46 KB (5,418 words) - 12:45, 29 August 2024
Antithrombin III deficiency (abbreviated ATIII deficiency) is a deficiency of antithrombin III. This deficiency may be inherited or acquired. It is a rare...
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Coagulation (section Antithrombin)
Factor V or high levels of FVIII, also may lead to a thrombotic tendency. Antithrombin is a serine protease inhibitor (serpin) that degrades the serine proteases:...
64 KB (6,553 words) - 17:35, 26 October 2024
pig intestines and bovine lungs. UFH binds to the enzyme inhibitor antithrombin III (AT), causing a conformational change that results in its activation...
78 KB (8,755 words) - 07:51, 27 October 2024
rechecking laboratory values. Use in antithrombin III deficiency: FFP can be used as a source of antithrombin III in patients who are deficient of this...
17 KB (1,769 words) - 09:45, 14 January 2024
(Rh(D) immunoglobulin G) Tetanus Immunoglobulin-VF Thrombotrol-VF (antithrombin III) Vivaglobin, sub-cutaneous human immune globulin indicated for the...
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hydrogen bonding. Some examples of heparin binding proteins include antithrombin III. It is thought that much protein interaction with heparin is not direct...
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particularly those caused by a decrease in blood antithrombin III levels due to leakage. Antithrombin III counteracts the action of thrombin. Thrombosis...
57 KB (6,362 words) - 01:53, 28 October 2024
compete for similar sites on factor Va. Factor Xa is inhibited by the antithrombin III/heparin system, which also acts to inhibit thrombin. Deficiencies of...
25 KB (3,112 words) - 19:03, 28 February 2024
S deficiency, activated protein C resistance (Factor V Leiden) and antithrombin III deficiency. Although the above hypothesis is the most commonly accepted...
11 KB (1,332 words) - 18:31, 11 March 2023
ovalbumin, to give what was initially called the alpha1-antitrypsin-antithrombin III-ovalbumin superfamily of serine proteinase inhibitors, but was subsequently...
137 KB (14,301 words) - 14:45, 2 November 2024
direct factor Xa inhibitors, it mediates its effects indirectly through antithrombin III, but unlike heparin, it is selective for factor Xa. Fondaparinux is...
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774–77. PMID 9666418. MedlinePlus Encyclopedia: 003652 Antithrombin III at eMedicine Antithrombin CO000300 in Coagulation Test Handbook at Massachusetts...
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By cause Clotting factors Antithrombin III deficiency Protein C deficiency Activated protein C resistance Protein S deficiency Factor V Leiden Prothrombin...
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Defekte von Antithrombin III, Protein C und Protein S" [Molecular biological basis and diagnosis of hereditary defect of antithrombin III, protein c and...
14 KB (1,762 words) - 13:30, 2 November 2024
Extracellular superoxide dismutase (SOD3) Angiotensin converting enzyme Antithrombin-III Lipoprotein lipase Apolipoproteins Growth factors Chemokines The enzymes...
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requiring CPB. A small percentage of patients, such as those with an antithrombin III deficiency, may exhibit resistance to heparin. In these patients, patients...
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proteins Coagulation: increase circulating level of factors 2, 7, 9, 10, antithrombin III, plasminogen increase platelet adhesiveness Fluid balance: salt (sodium)...
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mutation (3%), protein C deficiency (5%), protein S deficiency (4%), and antithrombin III deficiency(1%). Budd–Chiari syndrome may be the presenting sign of...
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divided into two functional subcategories, those that generate an antithrombin III binding site (HS3ST1 and HS3ST5) and those that generate a herpes simplex...
36 KB (4,151 words) - 11:14, 16 October 2024
cascade. Heparin works by binding to and activating the enzyme inhibitor antithrombin III, an enzyme that acts by inactivating thrombin and factor Xa. In contrast...
21 KB (2,279 words) - 02:02, 18 September 2024
lead to mutations through intrastrand and interstrand switching. The antithrombin III gene's coding region is an example of an imperfect inverted repeat...
31 KB (3,451 words) - 20:17, 11 September 2024
stroke or heart attack. Dalteparin acts by potentiating the activity of antithrombin III, inhibiting formation of both Factor Xa and thrombin. It is normally...
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screen- to detect chronic venous thromboembolism (proteins C and S, antithrombin III, homocysteine levels) The diagnosis of pulmonary heart disease is not...
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transaminase ASX asymptomatic A-T ataxia-telangiectasia AT antithrombin angiotensin AT-III antithrombin III ATA antitransglutaminase antibodies ATB antibiotic...
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an enormous variety of proteinases α2-macroglobulin α1-antitrypsin Antithrombin III Protein S Protein C Fibrinolysis: Breakdown of fibrin clots Plasminogen...
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moving fraction with a low molecular weight of 7000 Da and affinity for antithrombin III) and 20% dermatan sulfate with a high molecular weight (25,000 Da)...
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Leiden mutation, coagulation factor II G2021A mutation, deficiency of antithrombin III, protein C or S deficiency, nephrotic syndrome, changes after severe...
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thrombosis-thrombocytopenia syndrome. It does not require a binding cofactor such as antithrombin and does not activate platelets. These characteristics make bivalirudin...
28 KB (2,792 words) - 20:16, 23 April 2024
100 x 109 L-1) or by testing the levels of fibrin metabolites and antithrombin III.[citation needed] Elevated serum levels of certain proteins, in particular...
33 KB (3,744 words) - 07:18, 5 September 2024