Bradykinin (BK) (from Greek brady- 'slow' + -kinin, kīn(eîn) 'to move') is a peptide that promotes inflammation. It causes arterioles to dilate (enlarge)...

minutes to hours. The underlying mechanism typically involves histamine or bradykinin. The version related to histamine is due to an allergic reaction to agents...

enzyme in the bradykinin system, the ACE inhibitor drugs allow for increased levels of bradykinin which would normally be degraded. Bradykinin produces prostaglandin...

The bradykinin receptor family is a group of G-protein coupled receptors whose principal ligand is the protein bradykinin. There are two Bradykinin receptors:...

Bradykinin receptor B1 (B1) is a G-protein coupled receptor encoded by the BDKRB1 gene in humans. Its principal ligand is bradykinin, a 9 amino acid peptide...

selective COX-2 inhibitor and also inhibits bradykinin-induced pain responses without blocking bradykinin receptors. It was approved for use in Japan...

Bradykinin receptor B2 is a G-protein coupled receptor for bradykinin, encoded by the BDKRB2 gene in humans. The B2 receptor (B2R) is a G protein-coupled...

(type 2), this leads to bradykinin disinhibition and bradykinin mediated activation of bradykinin B1 receptor and bradykinin B2 receptor on endothelial...

cardiovascular diseases. Other lesser known functions of ACE are degradation of bradykinin, substance P and amyloid beta-protein. ACE is also known by the following...

activation of bradykinin B2 receptors. Icatibant acts as a bradykinin inhibitor by blocking the binding of native bradykinin to the bradykinin B2 receptor...

blood pressure control, coagulation and pain. Its important mediators bradykinin and kallidin are vasodilators and act on many cell types. Clinical symptoms...

Brazilian physician and pharmacologist noted for the discovery of the bradykinin potentiating factor, which led to new and widely used anti-hypertension...

Brazilian physician and biomedical scientist, one of the co-discoverers of bradykinin, together with Maurício Rocha e Silva and Wilson Teixeira Beraldo, in...

Gerais) was a Brazilian physician and physiologist, a co-discoverer of bradykinin. Beraldo graduated in medicine in 1942, having studied at the Federal...

angiotensin II and the inactivation of bradykinin were thought to be mediated by the same enzyme. In 1970, using bradykinin potentiating factor (BPF) provided...

Brazilian physician, biomedical scientist and pharmacologist. He discovered bradykinin, an endogenous polypeptide involved in the physiology, pharmacology and...

angiotensin II and may potentiate some of the pharmacological actions of bradykinin. It has a molecular formula of C53H76N14O12 and has been investigated...

release substances such as bradykinin and kallikrein inducing hypotension. Bradykinin-enhancing peptides interfere with the bradykinin metabolism causing it...

use in heart failure on July 7, 2015. Sacubitril increases levels of bradykinin, which is responsible for the edema seen sometimes in patients with the...

initiation of blood coagulation, and in the generation of the vasodilator bradykinin via the kallikrein-kinin system. HMWK is inactive until it either adheres...

lipoxygenases (LOX) (also known as: EC 1.13.11.34, EC 1.13.11.33, etc.). The bradykinin peptide is well known to promote a cough reaction associated with ACE...

A kinin is any of various structurally related polypeptides, such as bradykinin and kallidin. They are members of the autacoid family. Kinins are peptides...

converted to bradykinin by the aminopeptidase enzyme. It can be a substrate for carboxypeptidase M and N. Kallidin is identical to bradykinin with an additional...

production of bradykinin. The inhibition of FXIIa therefore prevents the activation of prekallikrein into kallikrein and the generation of bradykinin, which...

HK to form cHK, releasing a peptide known as bradykinin (BK). BK and its derivatives bind to bradykinin receptors B1 and B2 to mediate inflammation. Artificial...

that proteolytically cleaves high-molecular-weight kininogen to produce bradykinin, which is a vasodilator; it is secreted by the acinar cells of all three...

and is produced mostly by the liver. It is also a precursor protein for bradykinin. Low-molecular-weight-kininogen (LK) is mainly a precursor protein for...

bradykinin produced through Factor XII activation by negatively charged surfaces such as filters. When mechanisms for the degradation of bradykinin are...

protein → bradykinin peptide (9 amino acids) HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide...

isothiocyanate (mustard, radish, horseradish, wasabi) AM404 ASP-7663 Bradykinin Cannabichromene (cannabis) Cannabidiol (cannabis) Cannabigerol (cannabis)...