Integrin alpha L (redirect from Antigens, cd11a)
Integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide), also known as ITGAL, is a protein that in humans...
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endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by rhinovirus as a receptor...
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component is CD18 (β2) and mediate leukocyte adhesion. For example, LFA1 (CD11a/CD18) short representation of Lymphocyte Function-associated Antigen 1,...
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located on the αM chain (CD11b) and HNA-5 is located on the αL integrin unit (CD11a). Two functionally unequal subpopulations of neutrophils were identified...
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administered once weekly by subcutaneous injection. Efalizumab binds to the CD11a subunit of lymphocyte function-associated antigen 1 and acts as an immunosuppressant...
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determined for the I-domains of integrins CD11b (with bound magnesium) and CD11a (with bound manganese). The domain adopts a classic alpha/beta Rossmann...
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Otelixizumab Teplizumab Visilizumab CD4 Clenoliximab Keliximab Zanolimumab CD11a Efalizumab CD18 Erlizumab CD20 Obinutuzumab Ocrelizumab (+hyaluronidase)...
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integrins. The known binding partners of CD18 are CD11a, CD11b, CD11c and CD11d. Binding of CD18 and CD11a results in the formation of lymphocyte function-associated...
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CD11b, CD15+, CD24+, CD114+, CD182+ Monocyte CD4, CD45+, CD14+, CD114+, CD11a, CD11b, CD91+, CD16+ T lymphocyte CD45+, CD3+ T helper cell CD45+, CD3+...
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mouse EpCAM colorectal carcinoma Efalizumab Raptiva mab humanized LFA-1 (CD11a) psoriasis (blocks T-cell migration) Efungumab Mycograb scFv human Hsp90...
137 KB (4,083 words) - 21:25, 19 October 2024
alefacept. Efalizumab is a monoclonal antibody that specifically targets the CD11a subunit of LFA-1. It also blocks the adhesion molecules on the endothelial...
116 KB (13,058 words) - 21:40, 16 October 2024
The alpha subunit was named aL in 1983. The alpha subunit is designated CD11a; and the beta subunit, unique to leukocytes, is beta-2 or CD18. The ICAM...
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molecules, co-stimulatory molecules (CD80, CD86) and adhesion receptors (CD11a, CD18, CD54). Thus activated Vγ9Vδ2 T cells behave like APCs (γδ T-APC)...
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expressed in acute lymphocytic leukemia and follicular-center-cell lymphomas. CD11a Integrin Alpha L (ITGAL), the alpha subunit of LFA-1, a membrane glycoprotein...
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PRO827 ITGA11 ITGA11 HsT18964 ITGAD CD11D FLJ39841 ITGAE CD103 HUMINAE ITGAL CD11a LFA1A ITGAM CD11b MAC-1 ITGAV CD51 VNRA, MSK8 ITGA2B CD41 GPIIb ITGAX CD11c...
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Adhesion between FDCs and B cells is mediated by ICAM-1 (CD54)–LFA-1 (CD11a) and VCAM–VLA-4 molecules. Activated B-cells with low affinity to antigen...
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beta subunits Alpha subunits A1 A2 A3 A4 A5 A6 A7 A8 A9 A10 A11 AD AE AL (CD11a) AM (CD11b) AV AX (CD11c) Beta subunits B1 B2 B3 B4 B5 B6 B7 B8 Dimers Cytoadhesin...
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Kozhich AT, Magone MT (November 1999). "Blocking ICAM-1 (CD54) and LFA-1 (CD11a) inhibits experimental allergic conjunctivitis". Clinical Immunology. 93...
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"Human endothelial-cell specific molecule-1 binds directly to the integrin CD11a/CD18 (LFA-1) and blocks binding to intercellular adhesion molecule-1". J...
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with Decreased Frequency of Activated Memory/Effector T Cells Expressing CD11a+. Moleculary Theorie. doi:10.1016/j.ymthe.2020.10.001. PMID 33186542. Bacher...
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(telencephalin) and characterization of its interaction with the leukocyte integrin CD11a/CD18". Eur. J. Immunol. 30 (3): 810–8. doi:10.1002/1521-4141(200003)30:...
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R.; Pommer, A.J.; Malykh, Y.; Philipsen, L.; Gollnick, H. (2007). "The CD11a Binding Site of Efalizumab in Psoriatic Skin Tissue as Analyzed by Multi-Epitope...
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Jensen UB, et al. (November 2003). "RUNX/AML and C/EBP factors regulate CD11a integrin expression in myeloid cells through overlapping regulatory elements"...
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264.035.111 – antigens, cd11 MeSH D23.050.301.264.035.111.024 – antigens, cd11a MeSH D23.050.301.264.035.111.049 – antigens, cd11b MeSH D23.050.301.264...
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integrin alpha chains MeSH D12.776.543.750.705.408.100.100 – antigens, cd11a MeSH D12.776.543.750.705.408.100.150 – antigens, cd11b MeSH D12.776.543...
121 KB (11,308 words) - 16:43, 9 February 2024