Glucokinase (EC 2.7.1.2) is an enzyme that facilitates phosphorylation of glucose to glucose-6-phosphate. Glucokinase occurs in cells in the liver and...

The glucokinase regulatory protein (GKRP) also known as glucokinase (hexokinase 4) regulator (GCKR) is a protein produced in hepatocytes (liver cells)...

group from ATP to a substrate. Hexokinases should not be confused with glucokinase, which is a specific hexokinase found in the liver. All hexokinases are...

Glucokinase regulator is a protein that in humans is encoded by the GCKR gene. This gene encodes a protein belonging to the GCKR subfamily of the SIS...

is converted to F1P in the liver. This negates the action of F6P on glucokinase, which ultimately favors the forward reaction. The capacity of liver...

intracellular starch or glycogen. In animals, an isozyme of hexokinase called glucokinase is also used in the liver, which has a much lower affinity for glucose...

In enzymology, an ADP-specific glucokinase (EC 2.7.1.147) also known as ADP-dependent glucokinase is an enzyme that catalyzes the chemical reaction ADP...

mutations of transcription factor genes. One form is due to mutations of the glucokinase gene. For each form of MODY, multiple specific mutations involving different...

cells. Due to this, Glucokinase and glucokinase activators are the focus of treatment for those with type 2 diabetes mellitus. Glucokinase have a single allosteric...

Dorzagliatin is a glucokinase activator that is being developed to treat diabetes. Unlike other diabetes drugs, it is intended to increase insulin sensitivity...

first enzyme in the glycolysis pathway, has a specialized form called glucokinase expressed in the liver and pancreas that has a lower affinity for glucose...

for his contributions in diabetes research, specifically the work of Glucokinase activation as a treatment therapy for type 2 diabetes. Ramakanth Sarabu...

human chromosome 7 for glucokinase. Glucokinase serves as the glucose sensor for the pancreatic beta cell. Normal glucokinase triggers insulin secretion...

Catholic novelist and author GK Barry, English influencer and presenter Glucokinase, an enzyme that facilitates phosphorylation of glucose to glucose-6-phosphate...

there as a cellular glycogen. In the liver cell, it is phosphorylated by glucokinase at position 6 to form glucose 6-phosphate, which cannot leave the cell...

conventional glucokinase and phosphofructokinase, two novel sugar kinases have been discovered. These enzymes are ADP-dependent glucokinase (ADP-GK) and...

Cadisegliatin (TTP399) is a liver-selective glucokinase activator. It is being developed by VTV Therapeutics for treatment of type 2 diabetes or type...

encoding protein GEN1, Holliday junction 5' flap endonuclease GCKR: Glucokinase regulator GFPT1: glutamine—fructose-6-phosphate transaminase 1 GKN1:...

northwestern Iranian language branch, spoken in Iran's Gilan Province Glucokinase, an enzyme that facilitates phosphorylation of glucose to glucose-6-phosphate...

levels. Glucose is converted into glucose 6-phosphate by the action of glucokinase or hexokinase with conversion of ATP to ADP. Glucose-6-phosphate is converted...

Globalagliatin (SY-004) is a glucokinase activator developed by Yabao Pharmaceutical Group for type 2 diabetes. Zhao, Yuqing; Xie, Lijun; Zhang, Hongwen;...

fitness, and be favoured by natural selection. An example of an isozyme is glucokinase, a variant of hexokinase which is not inhibited by glucose 6-phosphate...

catalyzed by the enzyme hexokinase in most cells, and, in higher animals, glucokinase in certain cells, most notably liver cells. One equivalent of ATP is...

obesity and type 2 diabetes. This includes research identifying the genes glucokinase and HNF1 risk factors for type 2 diabetes. In 2007, he was elected to...

By contrast, glucose tends to pass through the liver (Km of hepatic glucokinase = 10 mM) and can be metabolised anywhere in the body. Uptake of fructose...

enters the β-cell is phosphorylated to glucose-6-phosphate (G-6-P) by glucokinase (hexokinase IV) which is not inhibited by G-6-P in the way that the hexokinases...

for hexokinase A (brain hexokinase) to about 50 mM for hexokinase D ("glucokinase", liver hexokinase), more than a 2000-fold range. It would be impossible...

gene (SCHAD-CHI) and glucokinase (GCK-CHI). More recently, changes in hexokinase 1 (HK1), another enzyme similar to glucokinase has been identified to...

insulin-producing pancreatic islets and ultimately discovered the essential role of glucokinase (liver and pancreas hexokinase) in the regulation of glucose-stimulated...

concentration gradient through the GLUT2 transporter. Since beta cells use glucokinase to catalyze the first step of glycolysis, metabolism only occurs around...