HLA-G histocompatibility antigen, class I, G, also known as human leukocyte antigen G (HLA-G), is a protein that in humans is encoded by the HLA-G gene...
21 KB (2,627 words) - 16:50, 20 January 2024
Human leukocyte antigen (redirect from HLA antigen)
and three minor MHC class I genes in HLA. Major MHC class I HLA-A HLA-B HLA-C Minor genes are HLA-E, HLA-F and HLA-G. β2-microglobulin binds with major...
51 KB (5,941 words) - 20:20, 27 June 2024
Human leukocyte antigen (HLA) B27 (subtypes B*2701-2759) is a class I surface molecule encoded by the B locus in the major histocompatibility complex...
16 KB (1,516 words) - 09:54, 16 February 2024
alloantigen). Nevertheless, the β2 microglobulin gene is outside of the MHC (HLA) locus, on a different chromosome. An additional function is association...
18 KB (2,119 words) - 21:11, 21 June 2024
HLA-DR4 (DR4) is an HLA-DR serotype that recognizes the DRB1*04 gene products. The DR4 serogroup is large and has a number of moderate frequency alleles...
26 KB (2,119 words) - 03:34, 29 November 2023
HLA-A is a group of human leukocyte antigens (HLA) that are encoded by the HLA-A locus, which is located at human chromosome 6p21.3. HLA is a major histocompatibility...
27 KB (3,411 words) - 01:57, 10 March 2024
polymorphic HLA-A (HLA-A) HLA-B (HLA-B) HLA-C (HLA-C) Less polymorphic HLA-E (HLA-E) HLA-F (HLA-F) HLA-G (HLA-G) HLA-K (pseudogene) HLA-L (pseudogene)...
21 KB (2,606 words) - 10:36, 17 July 2024
HLA-DR1 (DR1) is a HLA-DR serotype that recognizes the DRB1*01 gene products. It has been observed to be common among centenarians. The serology for the...
20 KB (1,596 words) - 01:46, 28 November 2023
HLA-C alleles that are Class-I MHC receptors. HLA-C, localized proximal to the HLA-B locus, is located on the distal end of the HLA region. Most HLA-C:B...
8 KB (1,014 words) - 03:35, 28 December 2023
HLA class I histocompatibility antigen, alpha chain F is a protein that in humans is encoded by the HLA-F gene. It is an empty intracellular molecule...
36 KB (4,439 words) - 06:11, 25 December 2023
HLA-DR is an MHC class II cell surface receptor encoded by the human leukocyte antigen complex on chromosome 6 region 6p21.31. The complex of HLA-DR (Human...
31 KB (2,293 words) - 12:25, 28 December 2023
HLA-DQ2 (DQ2) is a serotype group within HLA-DQ (DQ) serotyping system. The serotype is determined by the antibody recognition of β2 subset of DQ β-chains...
33 KB (3,380 words) - 17:14, 6 July 2024
HLA class II histocompatibility antigen, DQ(6) alpha chain is a protein that in humans is encoded by the HLA-DQA2 gene. Also known as HLA-DXA or DAAP-381D23...
10 KB (1,251 words) - 06:48, 11 July 2024
such as cancer. For example, associations between polymorphisms in the HLA-G 3′UTR region and development of colorectal cancer have been discovered....
12 KB (1,454 words) - 21:01, 18 January 2024
Tumor cells have non-classical MHC class I on their surface, for example HLA-G. HLA-G is inducer of Treg, MDSC, polarise macrophages into alternatively activated...
33 KB (3,766 words) - 14:14, 19 June 2024
MHC class II (redirect from Hla-d antigens)
gene complex (HLA). HLAs corresponding to MHC class II are HLA-DP, HLA-DM, HLA-DOA, HLA-DOB, HLA-DQ, and HLA-DR. Mutations in the HLA gene complex can...
16 KB (2,022 words) - 12:35, 15 July 2024
HLA-B51 (B51) is an HLA-B serotype. The serotype identifies the more common HLA-B*51 gene products. B51 is a split antigen of the broad antigen B5, and...
16 KB (960 words) - 01:10, 1 June 2024
the genomic regulation of HLA-G and how the presence of a LINE1 gene silencer may explain the limited expression of HLA-G. She also contributed to the...
12 KB (1,230 words) - 21:45, 14 July 2024
both classical MHC I (HLA-A, HLA-B, HLA-C) and nonclassical Mamu-G (HLA-G) in primates. Some KIRs are specific for certain HLA subtypes. Most KIRs are...
74 KB (9,180 words) - 04:00, 11 March 2024
HLA-B35 (B35) is an HLA-B serotype. The serotype identifies the more common HLA-B*35 gene products. B35 is one of the largest B serotype groups, it currently...
6 KB (149 words) - 14:44, 26 June 2024
cells to avoid immune system is upregulation of non-classical MHC I (HLA-E, HLA-F, HLA-G) which prevents NK-mediated immune reaction by interaction with NK...
11 KB (1,356 words) - 23:48, 15 December 2021
HLA class I histocompatibility antigen, alpha chain E (HLA-E) also known as MHC class I antigen E is a protein that in humans is encoded by the HLA-E...
7 KB (954 words) - 16:08, 1 April 2024
PMID 24480786. Rebmann V, Switala M, Eue I, Grosse-Wilde H (July 2010). "Soluble HLA-G is an independent factor for the prediction of pregnancy outcome after ART:...
173 KB (20,281 words) - 17:44, 22 July 2024
HLA-DQ8 (DQ8) is a human leukocyte antigen serotype within the HLA-DQ (DQ) serotype group. DQ8 is a split antigen of the DQ3 broad antigen. DQ8 is determined...
67 KB (5,460 words) - 15:43, 3 July 2024
of the HLA System revised the nomenclature for HLAs. Before this revision, HLA-A*02 was also referred to as HLA-A2, HLA-A02, and HLA-A*2. HLA-A*02 is...
31 KB (1,695 words) - 14:33, 26 June 2024
HLA-DR3 is composed of the HLA-DR17 and HLA-DR18 split 'antigens' serotypes. DR3 is a component gene-allele of the AH8.1 haplotype in Northern and Western...
9 KB (697 words) - 02:42, 27 January 2024
contact with the uterine wall - at the placental bed - begin to express the HLA-G antigen. Extravillous trophoblast (EVT) cells migrate from anchoring villi...
13 KB (1,535 words) - 22:29, 23 March 2023
HLA class II histocompatibility antigen, DRB1 beta chain is a protein that in humans is encoded by the HLA-DRB1 gene. DRB1 encodes the most prevalent beta...
6 KB (688 words) - 11:10, 3 February 2024
shown to play a role in downregulating MHC I and MHC II and up regulating HLA-G (non-classical MHC I). These two events allow for immune evasion by suppressing...
31 KB (2,887 words) - 04:06, 18 June 2024
HLA-DR15 (DR15) is a HLA-DR serotype that recognizes the DRB1*1501 to *1505 and *1507 gene products. DR15 is found at high levels from Ireland to Central...
16 KB (1,100 words) - 13:55, 26 March 2024