• Thumbnail for HMG-box
    In molecular biology, the HMG-box (high mobility group box) is a protein domain which is involved in DNA binding. The domain is composed of approximately...
    4 KB (346 words) - 08:11, 3 June 2024
  • containing any of these embedded in their sequence are known as HMG motif proteins. HMG-box proteins are found in a variety of eukaryotic organisms. They...
    5 KB (545 words) - 02:57, 18 June 2024
  • SOX genes (SRY-related HMG-box genes) encode a family of transcription factors that bind to the minor groove in DNA, and belong to a super-family of genes...
    6 KB (715 words) - 06:15, 3 June 2024
  • Thumbnail for HMGB1
    group box 1 protein, also known as high-mobility group protein 1 (HMG-1) and amphoterin, is a protein that in humans is encoded by the HMGB1 gene. HMG-1 belongs...
    26 KB (3,154 words) - 13:09, 6 March 2024
  • another helix. The larger helix typically contains the DNA-binding regions. HMG-box domains are found in high mobility group proteins which are involved in...
    19 KB (2,157 words) - 07:17, 19 July 2024
  • Thumbnail for Sex-determining region Y protein
    sequence also changes; while the core of the gene, the high-mobility group (HMG) box, is conserved between species, other regions of the gene are not. SRY is...
    39 KB (4,851 words) - 19:45, 29 June 2024
  • Thumbnail for HMGXB4
    HMGXB4 (redirect from Hmg-box containing 4)
    HMG-box containing 4 is a protein that in humans is encoded by the HMGXB4 gene. High mobility group (HMG) proteins are nonhistone chromosomal proteins...
    3 KB (374 words) - 11:39, 4 March 2023
  • Thumbnail for UBTF
    chromosome 11 [citation needed]. UBTF contains six high mobility group boxes (HMG-boxes) that allow it to bind to DNA. UBTF also contains a hyperacidic carboxy-terminal...
    19 KB (2,154 words) - 04:04, 28 November 2023
  • Thumbnail for TOX
    mobility group protein 1). Some high mobility group (HMG) box proteins (e.g., LEF1) contain a single HMG box motif and bind DNA in a sequence-specific manner...
    18 KB (1,814 words) - 11:30, 25 August 2023
  • almost identical HMG-box DNA-binding domains which function to modify chromatin structure. "Entrez Gene: TOX high mobility group box family member 2"...
    2 KB (156 words) - 02:28, 29 November 2023
  • Thumbnail for TCF7
    Medicine. "Entrez Gene: TCF7 transcription factor 7 (T-cell specific, HMG-box)". van de Wetering M, Oosterwegel M, Holstege F, et al. (1992). "The human...
    5 KB (723 words) - 04:37, 1 April 2024
  • Thumbnail for Campomelic dysplasia
    heterozygous SOX9 mutations can cause CMD: amino acid substitutions in the HMG-box, truncations or frameshifts that alter the C-terminal end, mutations at...
    9 KB (1,003 words) - 03:09, 10 May 2024
  • Thumbnail for HMGXB3
    HMG-box containing 3 is a protein that in humans is encoded by the HMGXB3 gene. This gene is one of the non-canonical high mobility group (HMG) genes....
    707 bytes (124 words) - 09:46, 17 October 2022
  • Thumbnail for Lamb-Shaffer syndrome
    tongue groove This condition is caused by mutations in the SRY-related HMG-box (SOX5) gene. This gene encodes a protein in the family of transcription...
    5 KB (562 words) - 16:56, 1 July 2024
  • Thumbnail for WDHD1
    WD repeat and HMG-box DNA binding protein 1 is a protein in humans that is encoded by the WDHD1 gene. The protein encoded by this gene contains multiple...
    1 KB (160 words) - 06:53, 29 June 2024
  • Thumbnail for HBP1
    HMG-box transcription factor 1, also known as HBP1, is a human protein. HBP1 has been shown to interact with SIN3A and Retinoblastoma protein. ENSG00000283847...
    8 KB (972 words) - 11:27, 24 December 2023
  • Thumbnail for BBX (gene)
    HMG box transcription factor BBX also known as bobby sox homolog or HMG box-containing protein 2 is a protein that in humans is encoded by the BBX gene...
    3 KB (401 words) - 06:30, 18 December 2023
  • Thumbnail for TCF7L2
    Transcription factor 7-like 2 (T-cell specific, HMG-box), also known as TCF7L2 or TCF4, is a protein acting as a transcription factor that, in humans...
    44 KB (4,312 words) - 02:22, 16 July 2024
  • Thumbnail for DNA-binding protein
    simulation software DNA-binding domain Helix-loop-helix Helix-turn-helix HMG-box Leucine zipper Lexitropsin (a semi-synthetic DNA-binding ligand) Deoxyribonucleoprotein...
    21 KB (2,565 words) - 09:33, 10 June 2024
  • regions devoid of histones become very fragile after transcription; HMO1, an HMG-box protein, helps in stabilizing nucleosomes-free chromatin. A variety of...
    53 KB (5,924 words) - 16:38, 18 July 2024
  • Thumbnail for SOX3
    encoded by the SOX3 gene. This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic...
    11 KB (1,448 words) - 21:06, 6 January 2024
  • determining region Y)-box 30 is a protein that in humans is encoded by the SOX30 gene. This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription...
    3 KB (304 words) - 11:33, 18 August 2023
  • Thumbnail for Transcription factor
    factors 4.6 Class: TATA binding proteins 4.6.1 Family: TBP 4.7 Class: HMG-box 4.7.1 Family: SOX genes, SRY 4.7.2 Family: TCF-1 (TCF1) 4.7.3 Family: HMG2-related...
    75 KB (8,023 words) - 07:06, 3 June 2024
  • Thumbnail for Capicua (protein)
    The two evolutionarily conserved domains of the protein are HMG-box (high-mobility group box) and the C1 domain: they work together to recognize specific...
    12 KB (1,435 words) - 00:30, 4 July 2024
  • hypopigmentation syndrome is a condition caused by a mutation on the SRY-related HMG-box gene 10 (not SOX10). It was characterized in 1990, after being seen in...
    4 KB (263 words) - 06:20, 5 January 2021
  • Thumbnail for SOX1
    SOX1 is a gene that encodes a transcription factor with a HMG-box (high mobility group) DNA-binding domain and functions primarily in neurogenesis. SOX1...
    5 KB (593 words) - 06:42, 3 June 2024
  • tggctgTGACgccacaaaggc SOX/SRY-sex/testis determining and related HMG box factors 438 462 + cctgaAGAAtggttgccttggagac X-box binding factors 449 469 - ggtttacgtctccaAGGCaac...
    10 KB (820 words) - 13:16, 21 April 2024
  • Thumbnail for Proser2
    C2HC zinc finger protein, SOX/SRY– sex/testis determining and related HMG box factors, CCAAT binding factors, HOX-PBX complexes, and C2HC zinc finger...
    20 KB (1,894 words) - 12:35, 14 February 2023
  • Thumbnail for SOX4
    SOX4 gene. This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic...
    11 KB (1,173 words) - 21:38, 17 August 2023
  • solved the structure of the A-box/p53 complex formed by the interaction between the N-terminus of p53 and a single HMG-box of HMGB1. Recently, she studied...
    17 KB (1,589 words) - 22:11, 6 November 2023