• Thumbnail for Hepatocyte
    A hepatocyte is a cell of the main parenchymal tissue of the liver. Hepatocytes make up 80% of the liver's mass. These cells are involved in: Protein...
    14 KB (1,621 words) - 06:14, 20 August 2024
  • Thumbnail for Hepatocyte growth factor
    Hepatocyte growth factor (HGF) or scatter factor (SF) is a paracrine cellular growth, motility and morphogenic factor. It is secreted by mesenchymal cells...
    23 KB (2,635 words) - 06:03, 24 August 2024
  • Thumbnail for Ballooning degeneration
    degeneration, formally ballooning degeneration of hepatocytes, is a form of liver parenchymal cell (i.e. hepatocyte) death. The name is derived from the fact...
    3 KB (332 words) - 21:11, 13 June 2024
  • Thumbnail for Ground glass hepatocyte
    In liver pathology, a ground glass hepatocyte, abbreviated GGH, is a liver parenchymal cell with a flat hazy and uniformly dull appearing cytoplasm on...
    4 KB (398 words) - 08:37, 10 June 2024
  • Hepatocyte nuclear factors (HNFs) are a group of phylogenetically unrelated transcription factors that regulate the transcription of a diverse group of...
    8 KB (585 words) - 20:31, 30 May 2024
  • Thumbnail for Hepatocyte nuclear factor 4 alpha
    Hepatocyte nuclear factor 4 alpha (HNF4A) also known as NR2A1 (nuclear receptor subfamily 2, group A, member 1) is a nuclear receptor that in humans is...
    18 KB (2,230 words) - 15:35, 22 August 2024
  • Thumbnail for Hepatocyte growth factor receptor
    Hepatocyte growth factor receptor (HGF receptor) is a protein that in humans is encoded by the MET gene. The protein possesses tyrosine kinase activity...
    58 KB (6,927 words) - 03:33, 17 June 2024
  • Thumbnail for Feathery degeneration
    degeneration, formally feathery degeneration of hepatocytes, is a form of liver parenchymal cell (i.e. hepatocyte) death associated with cholestasis. Cells...
    2 KB (132 words) - 21:12, 29 July 2023
  • Thumbnail for Dihexa
    oligopeptide drug derived from angiotensin IV that binds with high affinity to hepatocyte growth factor (HGF) and potentiates its activity at its receptor, c-Met...
    6 KB (460 words) - 19:16, 8 July 2024
  • Thumbnail for Alcoholic hepatitis
    hepatitis also leads to impaired hepatocyte differentiation, impairments in hepatocyte regeneration and hepatocyte de-differentiation into cholangiocyte...
    21 KB (2,285 words) - 13:31, 4 June 2024
  • When hepatocytes cannot proliferate, biliary epithelial cells are capable of turning into hepatocytes. The reverse can also occur, with hepatocytes turning...
    22 KB (2,472 words) - 03:27, 22 June 2024
  • Thumbnail for Hepatocyte nuclear factor 4 gamma
    Hepatocyte nuclear factor 4 gamma (HNF4G) also known as NR2A2 (nuclear receptor subfamily 2, group A, member 2) is a nuclear receptor that in humans is...
    4 KB (417 words) - 13:51, 10 July 2024
  • Thumbnail for Cholestasis
    hepatocytes. Bile infarcts are marked by a large amount of pigmented tissue surrounded by a ring of necrotic hepatocytes. In some cases, hepatocyte degeneration...
    112 KB (12,703 words) - 07:34, 10 August 2024
  • Thumbnail for Perisinusoidal space
    a location in the liver between a hepatocyte and a sinusoid. It contains the blood plasma. Microvilli of hepatocytes extend into this space, allowing proteins...
    3 KB (241 words) - 15:01, 13 January 2024
  • Thumbnail for MST1
    Macrophage-stimulating protein (MSP), also known as hepatocyte growth factor-like protein (HLP, HGFL, or HGFLP), is a protein that in humans is encoded...
    7 KB (901 words) - 22:17, 3 March 2023
  • Thumbnail for Liver
    digestion. The liver's highly specialized tissue, consisting mostly of hepatocytes, regulates a wide variety of high-volume biochemical reactions, including...
    86 KB (10,225 words) - 11:45, 23 August 2024
  • Thumbnail for Councilman body
    hyaline body or apoptotic body, is an eosinophilic globule of apoptotic hepatocyte cell fragments. Ultimately, the fragments are taken up by macrophages...
    2 KB (147 words) - 08:57, 2 July 2024
  • Thumbnail for HNF1B
    homeobox B (hepatocyte nuclear factor 1 homeobox B), also known as HNF1B or transcription factor 2 (TCF2), is a human gene. HNF1B encodes hepatocyte nuclear...
    9 KB (1,254 words) - 20:30, 30 May 2024
  • HNF4 (Hepatocyte Nuclear Factor 4) is a nuclear receptor protein mostly expressed in the liver, gut, kidney, and pancreatic beta cells that is critical...
    5 KB (536 words) - 19:30, 14 June 2023
  • with liver regeneration, with a specific focus on the significance of hepatocyte growth factor (HGF) and its receptor (MET), as well as the role of the...
    25 KB (2,734 words) - 13:16, 28 June 2024
  • Thumbnail for Mammal
    (February 1985). "Ultraviolet light-induced DNA repair synthesis in hepatocytes from species of differing longevities". Mechanisms of Ageing and Development...
    221 KB (23,066 words) - 21:32, 28 August 2024
  • mellitus. Oxytocin (OXT) Omentin Endothelin-1 Nesfatin-1 Irisin Betatrophin Hepatocyte growth factor (HGF) Fibroblast growth factor -Biomarkers with insulin-sensitizing...
    17 KB (2,133 words) - 18:38, 20 August 2024
  • Thumbnail for Hepatotoxicity
    models (e.g. DTI), and drug screening assays, such as stem cell-derived hepatocyte-like cells, that are capable of detecting toxicity early in the drug development...
    39 KB (4,074 words) - 11:25, 31 July 2024
  • Thumbnail for Hep G2
    model system for the study of polarized human hepatocytes. Another well-characterized polarized hepatocyte cell line is the rat hepatoma-derived hybrid...
    5 KB (577 words) - 05:27, 3 January 2023
  • Thumbnail for HepaRG
    injury. The HepaRG model is considered a surrogate for Primary Human Hepatocytes, which are the most pertinent model to reproduce the human liver functioning...
    25 KB (2,666 words) - 15:23, 29 June 2024
  • performed analysis on transaminases in 1957. The proportion of AST to ALT in hepatocytes is about 2.5:1, but because AST is removed from serum by the liver sinusoidal...
    9 KB (974 words) - 04:11, 1 July 2024
  • Thumbnail for Iron overload
    transported across intestinal enterocytes or mobilized out of storage in liver hepatocytes or from macrophages in the bone marrow by the transmembrane ferroportin...
    46 KB (4,693 words) - 09:51, 14 August 2024
  • Thumbnail for 2C-B
    Mice hepatocytes produce 4-bromo-2,5-dimethoxy-phenol (BDMP), a previously unknown metabolite. Meanwhile, human, monkey and rabbit hepatocytes produce...
    38 KB (4,145 words) - 14:25, 28 August 2024
  • Thumbnail for Keratin
    cytoskeleton organization KRT18 extrinsic apoptotic signaling pathway KRT18 hepatocyte apoptotic process KRT18 cell-cell adhesion KRT19 Notch signaling pathway...
    39 KB (3,016 words) - 15:08, 13 July 2024
  • Thumbnail for Intrahepatic bile ducts
    simple cuboidal epithelium, then by hepatocytes Bile canaliculi - two half-canaliculi formed by the hepatocytes facing the perisinusoidal space Standring...
    2 KB (149 words) - 14:42, 10 March 2022