shaker-related subfamily, member 3, also known as KCNA3 or Kv1.3, is a protein that in humans is encoded by the KCNA3 gene. Potassium channels represent the most...
36 KB (4,367 words) - 22:37, 16 July 2024
non-inactivating Kvα1.x - Shaker-related: Kv1.1 (KCNA1), Kv1.2 (KCNA2), Kv1.3 (KCNA3), Kv1.5 (KCNA5), Kv1.6 (KCNA6), Kv1.7 (KCNA7), Kv1.8 (KCNA10) Kvα2.x - Shab-related:...
17 KB (1,769 words) - 15:18, 22 June 2024
shaker gene is located on the X chromosome. The closest human homolog is KCNA3. The Sh gene plays a part in the operation of potassium ion channels, which...
8 KB (841 words) - 06:44, 11 October 2024
studying of clofazimine in human T cells revealed that this drug is a Kv1.3 (KCNA3) channel blocker. This indicates that clofazimine will be potentially used...
22 KB (1,951 words) - 05:03, 30 October 2024
HGNC:20589 Q9P0J7 7966 KCNA1 HGNC:6218 Q09470 7967 KCNA2 HGNC:6220 P16389 7968 KCNA3 HGNC:6221 P22001 7969 KCNA4 HGNC:6222 P22459 7970 KCNA5 HGNC:6224 P22460...
277 KB (17 words) - 18:41, 6 October 2024
family, and selectively blocks the voltage-gated potassium channel Kv1.3 (KCNA3). Odonthobuthus doriae is a scorpion species that belongs to the Buthidae...
8 KB (808 words) - 09:26, 26 October 2021
subfamily and targets the voltage-gated potassium channels KCNA2 (Kv1.2), and KCNA3 (Kv1.3). OSK3 is secreted from the venom gland of Orthochirus scrobiculosus...
7 KB (777 words) - 04:57, 24 November 2023
(K+) channel-blocking peptides. An important physiological role of the KCNA3 channel, also known as KV1.3, is to help maintain large electrical gradients...
16 KB (1,572 words) - 21:15, 16 April 2024
and Kv1.3. These channels are coded respectively by the genes KCNA2 and KCNA3 and their inhibition is reversible. hKv1.2 is inhibited with a Kd of 92...
4 KB (501 words) - 18:46, 17 October 2024
for Kv1.2/KCNA2, 2245.93 nM for Kv1.6/KCNA6, 1006.48 nM for human Kv1.3/KCNA3, and 94.25 nM for the Drosophila Shaker IR channels. Competitive interaction...
3 KB (327 words) - 18:59, 4 November 2023
John Kendrew Journal of Applied Biomechanics Julia Goodfellow KCNA10 KCNA2 KCNA3 KCNA4 KCNA5 KCNA6 KCNA7 KCNAB1 KCNAB2 KCNAB3 KCNB1 KCNB2 KCNC1 KCNC2 KCNC3...
15 KB (1,545 words) - 18:32, 17 August 2024
multiple sclerosis (MS) treatment. In macrophages, knock-down experiments of kcna3 (gene of Kv1.3) impaired cell growth and migration, features characteristic...
9 KB (1,043 words) - 02:05, 6 January 2024
RYR2; RYR3 Kvα1.x - Shaker-related: Kv1.1 (KCNA1), Kv1.2 (KCNA2), Kv1.3 (KCNA3), Kv1.5 (KCNA5), Kv1.6 (KCNA6), Kv1.7 (KCNA7), Kv1.8 (KCNA10) Kvα2.x - Shab-related:...
19 KB (1,692 words) - 03:53, 29 November 2023
proteins that contain the BTB/POZ domain. BTBD10; KCNA1; KCNA10; KCNA2; KCNA3; KCNA4; KCNA5; KCNA6; KCNA7; KCNB1; KCNB2; KCNC1; KCNC2; KCNC3; KCNC4; KCND1;...
10 KB (1,204 words) - 16:24, 3 December 2023
potent blocker of Kv1.3 (Kd= 0.73 nM) potassium channels. Besides Kv1.3/KCNA3 channels, Anuroctoxin also significantly inhibits Kv1.2 (Kd = 6 nM) potassium...
3 KB (438 words) - 11:43, 23 October 2021
region of this gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1. KCNA2 has been shown to interact with KCNA4...
12 KB (1,518 words) - 22:32, 16 July 2024
assignment of the gene encoding Kv1.3, a voltage-gated potassium channel (KCNA3) to the proximal short arm of human chromosome 1". Genomics. 23 (1): 295–6...
8 KB (979 words) - 07:05, 18 December 2023
KCNA2 gene and a less potent blocker of Kv1.3 channels, encoded by the KCNA3 gene and it also shows effect on voltage-gated rapidly inactivating A-type...
15 KB (1,616 words) - 00:38, 8 November 2023
Biochimie. 80 (2): 151–4. doi:10.1016/s0300-9084(98)80021-7. PMID 9587672. KCNA3 Cheong A, Li J, Sukumar P, Kumar B, Zeng F, Riches K, Munsch C, Wood IC...
14 KB (1,803 words) - 08:02, 8 May 2024
region of this gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1 in humans. KCNA4 (Kv1.4) contains a tandem inactivation...
15 KB (1,799 words) - 23:37, 16 July 2024
KCNAB3 Identifiers Aliases KCNAB3, AKR6A9, KCNA3.1B, KCNA3B, KV-BETA-3, potassium voltage-gated channel subfamily A regulatory beta subunit 3 External...
2 KB (346 words) - 22:39, 16 July 2024
Lerner DJ, Abbott GW (December 2011). "KCNE2 forms potassium channels with KCNA3 and KCNQ1 in the choroid plexus epithelium". FASEB Journal. 25 (12): 4264–73...
27 KB (3,525 words) - 00:03, 17 July 2024