• Thumbnail for Kynurenine
    l-Kynurenine is a metabolite of the amino acid l-tryptophan used in the production of niacin. Kynurenine is synthesized by the enzyme tryptophan dioxygenase...
    22 KB (2,100 words) - 22:40, 4 June 2024
  • Thumbnail for Kynurenine pathway
    the kynurenine pathway include tryptophan, kynurenine, kynurenic acid, xanthurenic acid, quinolinic acid, and 3-hydroxykynurenine. The kynurenine pathway...
    23 KB (2,404 words) - 17:15, 11 April 2024
  • Thumbnail for Kynurenine 3-monooxygenase
    kynurenine 3-monooxygenase (EC 1.14.13.9) is an enzyme that catalyzes the chemical reaction L-kynurenine + NADPH + H+ + O2 ⇌ 3-hydroxy-L-kynurenine +...
    18 KB (1,970 words) - 10:11, 22 March 2024
  • In enzymology, a kynurenine-glyoxylate transaminase (EC 2.6.1.63) is an enzyme that catalyzes the chemical reaction: L-kynurenine + glyoxylate ⇌ {\displaystyle...
    1 KB (107 words) - 14:38, 26 August 2023
  • Thumbnail for Ketamine
    Dasolampanel DNQX Fanapanel (MPQX) GAMS Kaitocephalin Kynurenic acid Kynurenine Licostinel (ACEA-1021) NBQX PNQX Selurampanel Tezampanel Theanine Topiramate...
    118 KB (11,372 words) - 06:12, 22 August 2024
  • Thumbnail for Tryptophan
    (TDO) in the liver, are responsible for the synthesis of kynurenine from tryptophan. The kynurenine pathway of tryptophan catabolism is altered in several...
    46 KB (4,555 words) - 17:25, 29 July 2024
  • Thumbnail for N'-Formylkynurenine
    intermediate in the catabolism of tryptophan. It is a formylated derivative of kynurenine. The formation of N′-formylkynurenine is catalyzed by heme dioxygenases...
    2 KB (87 words) - 09:44, 16 May 2024
  • In enzymology, a kynurenine 7,8-hydroxylase (EC 1.14.99.2) is an enzyme that catalyzes the chemical reaction kynurenate + AH2 + O2 ⇌ {\displaystyle \rightleftharpoons...
    2 KB (164 words) - 14:38, 26 August 2023
  • Thumbnail for Nitrous oxide
    Dasolampanel DNQX Fanapanel (MPQX) GAMS Kaitocephalin Kynurenic acid Kynurenine Licostinel (ACEA-1021) NBQX PNQX Selurampanel Tezampanel Theanine Topiramate...
    96 KB (10,049 words) - 21:10, 21 August 2024
  • Thumbnail for Zinc
    Dasolampanel DNQX Fanapanel (MPQX) GAMS Kaitocephalin Kynurenic acid Kynurenine Licostinel (ACEA-1021) NBQX PNQX Selurampanel Tezampanel Theanine Topiramate...
    143 KB (16,239 words) - 09:58, 22 August 2024
  • Thumbnail for Mitochondrion
    monoamine oxidase, rotenone-insensitive NADH-cytochrome c-reductase, kynurenine hydroxylase and fatty acid Co-A ligase. Disruption of the outer membrane...
    166 KB (18,360 words) - 18:19, 4 August 2024
  • Thumbnail for Furosemide
    Dasolampanel DNQX Fanapanel (MPQX) GAMS Kaitocephalin Kynurenic acid Kynurenine Licostinel (ACEA-1021) NBQX PNQX Selurampanel Tezampanel Theanine Topiramate...
    37 KB (3,650 words) - 17:39, 27 July 2024
  • Thumbnail for Kynurenine—oxoglutarate transaminase
    In enzymology, a kynurenine-oxoglutarate transaminase (EC 2.6.1.7) is an enzyme that catalyzes the chemical reaction L-kynurenine + 2-oxoglutarate ⇌ 4-(2-aminophenyl)-2...
    7 KB (671 words) - 16:12, 30 December 2023
  • Thumbnail for Dementia
    mild cognitive impairment (MCI) and mild behavioral impairment (MBI). Kynurenine is a metabolite of tryptophan that regulates microbiome signalling, immune...
    202 KB (22,761 words) - 21:36, 17 August 2024
  • Thumbnail for Glutathione
    β-Hydroxy β-methylglutaryl-CoA tryptophan→alanine→ N′-Formylkynurenine Kynurenine Anthranilic acid 3-Hydroxykynurenine 3-Hydroxyanthranilic acid 2-Amino-3-carboxymuconic...
    22 KB (2,179 words) - 16:41, 31 May 2024
  • Thumbnail for Alcohol (drug)
    Dasolampanel DNQX Fanapanel (MPQX) GAMS Kaitocephalin Kynurenic acid Kynurenine Licostinel (ACEA-1021) NBQX PNQX Selurampanel Tezampanel Theanine Topiramate...
    236 KB (24,256 words) - 04:19, 20 August 2024
  • Thumbnail for Phencyclidine
    Dasolampanel DNQX Fanapanel (MPQX) GAMS Kaitocephalin Kynurenic acid Kynurenine Licostinel (ACEA-1021) NBQX PNQX Selurampanel Tezampanel Theanine Topiramate...
    56 KB (5,405 words) - 23:32, 12 August 2024
  • Thumbnail for Magnesium
    Dasolampanel DNQX Fanapanel (MPQX) GAMS Kaitocephalin Kynurenic acid Kynurenine Licostinel (ACEA-1021) NBQX PNQX Selurampanel Tezampanel Theanine Topiramate...
    77 KB (8,474 words) - 14:50, 11 August 2024
  • Dasolampanel DNQX Fanapanel (MPQX) GAMS Kaitocephalin Kynurenic acid Kynurenine Licostinel (ACEA-1021) NBQX PNQX Selurampanel Tezampanel Theanine Topiramate...
    59 KB (5,621 words) - 21:25, 21 August 2024
  • Thumbnail for Methadone
    Dasolampanel DNQX Fanapanel (MPQX) GAMS Kaitocephalin Kynurenic acid Kynurenine Licostinel (ACEA-1021) NBQX PNQX Selurampanel Tezampanel Theanine Topiramate...
    77 KB (7,776 words) - 12:25, 16 August 2024
  • Thumbnail for Drosophila melanogaster
    ommochromes are synthesised from kynurenine, which is made from tryptophane. Vermilion flies cannot convert tryptophane into kynurenine and thus cannot make ommochromes...
    144 KB (16,609 words) - 15:43, 11 August 2024
  • Thumbnail for Tramadol
    Dasolampanel DNQX Fanapanel (MPQX) GAMS Kaitocephalin Kynurenic acid Kynurenine Licostinel (ACEA-1021) NBQX PNQX Selurampanel Tezampanel Theanine Topiramate...
    97 KB (9,171 words) - 03:59, 8 August 2024
  • Thumbnail for Quinolinic acid
    biosynthetic precursor to niacin. Quinolinic acid is a downstream product of the kynurenine pathway, which metabolizes the amino acid tryptophan. It acts as an NMDA...
    31 KB (3,477 words) - 18:51, 20 November 2023
  • Thumbnail for Kynureninase
    Kynureninase or L-Kynurenine hydrolase (KYNU) (EC 3.7.1.3) is a PLP dependent enzyme that catalyses the cleavage of kynurenine (Kyn) into anthranilic acid...
    8 KB (941 words) - 06:52, 3 June 2024
  • Thumbnail for Arginine
    β-Hydroxy β-methylglutaryl-CoA tryptophan→alanine→ N′-Formylkynurenine Kynurenine Anthranilic acid 3-Hydroxykynurenine 3-Hydroxyanthranilic acid 2-Amino-3-carboxymuconic...
    32 KB (3,156 words) - 17:50, 11 July 2024
  • Thumbnail for Nitric oxide
    Dasolampanel DNQX Fanapanel (MPQX) GAMS Kaitocephalin Kynurenic acid Kynurenine Licostinel (ACEA-1021) NBQX PNQX Selurampanel Tezampanel Theanine Topiramate...
    29 KB (2,758 words) - 02:52, 22 June 2024
  • Thumbnail for Major depressive disorder
    indolamine, IDO. IDO causes tryptophan to get converted into kynurenine and kynurenine becomes quinolinic acid. Quinolinic acid is an agonist for NMDA...
    189 KB (21,097 words) - 11:38, 22 August 2024
  • Dasolampanel DNQX Fanapanel (MPQX) GAMS Kaitocephalin Kynurenic acid Kynurenine Licostinel (ACEA-1021) NBQX PNQX Selurampanel Tezampanel Theanine Topiramate...
    21 KB (1,923 words) - 03:58, 21 July 2024
  • Thumbnail for Glycine
    β-Hydroxy β-methylglutaryl-CoA tryptophan→alanine→ N′-Formylkynurenine Kynurenine Anthranilic acid 3-Hydroxykynurenine 3-Hydroxyanthranilic acid 2-Amino-3-carboxymuconic...
    38 KB (3,403 words) - 03:29, 5 August 2024
  • Thumbnail for Glutamine
    Dasolampanel DNQX Fanapanel (MPQX) GAMS Kaitocephalin Kynurenic acid Kynurenine Licostinel (ACEA-1021) NBQX PNQX Selurampanel Tezampanel Theanine Topiramate...
    28 KB (2,559 words) - 18:51, 12 July 2024