Leucine (symbol Leu or L) is an essential amino acid that is used in the biosynthesis of proteins. Leucine is an α-amino acid, meaning it contains an α-amino...

β-Leucine (beta-leucine) is a beta amino acid and positional isomer of L-leucine which is naturally produced in humans via the metabolism of L-leucine by...

A leucine zipper (or leucine scissors) is a common three-dimensional structural motif in proteins. They were first described by Landschulz and collaborators...

The leucines are primarily the four isomeric amino acids: leucine, isoleucine, tert-leucine (terleucine, pseudoleucine) and norleucine. Being compared...

In enzymology, a leucine dehydrogenase (EC 1.4.1.9) is an enzyme that catalyzes the chemical reaction L-leucine + H2O + NAD+ ⇌ {\displaystyle \rightleftharpoons...

A leucine-rich repeat (LRR) is a protein structural motif that forms an α/β horseshoe fold. It is composed of repeating 20–30 amino acid stretches that...

(N-acetyl-leucine) is a modified leucine amino acid used in the treatment of vertigo and cerebellar ataxia. Two forms exist: acetyl-DL-leucine (sold under...

carbon atoms). Among the proteinogenic amino acids, there are three BCAAs: leucine, isoleucine, and valine. Non-proteinogenic BCAAs include 2-aminoisobutyric...

C. Levacetylleucine is a modified version of the amino acid leucine (N-Acetyl-L-Leucine). It is taken by mouth. The most common side effects include...

In enzymology, a leucine transaminase (EC 2.6.1.6) is an enzyme that catalyzes the chemical reaction L-leucine + 2-oxoglutarate ⇌ {\displaystyle \rightleftharpoons...

include hypoglycemia leucine-induced; hypoglycemia leucine induced; and familial infantile hypoglycemia precipitated by leucine. "Leucine-sensitive hypoglycemia...

(BCKAD) complex. It particularly affects the metabolism of amino acids—leucine, isoleucine, and valine. With MSUD, the body is not able to properly break...

In enzymology, a leucine N-acetyltransferase (EC 2.3.1.66) is an enzyme that catalyzes the chemical reaction acetyl-CoA + L-leucine ⇌ {\displaystyle \rightleftharpoons...

receptors, or NOD-like receptors (NLRs) (also known as nucleotide-binding leucine-rich repeat receptors), are intracellular sensors of pathogen-associated...

Leucine-rich repeat kinase 2 (LRRK2), also known as dardarin (from the Basque word "dardara" which means trembling) and PARK8 (from early identified association...

Leucine responsive protein, or Lrp, is a global regulator protein, meaning that it regulates the biosynthesis of leucine, as well as the other branched-chain...

transamination of the α-ketoisocaproate by the action of a glutamate-leucine transaminase. Leucine, like valine, regulates the first step of its pathway by inhibiting...

(HMB-Ca, CaHMB). Since only a small fraction of HMB's metabolic precursor, L-leucine, is metabolized into HMB, pharmacologically active concentrations of the...

for "N-Acetyl-L-Leucine for Ataxia-Telangiectasia (A-T)" at ClinicalTrials.gov Clinical trial number NCT03759639 for "N-Acetyl-L-Leucine for Niemann-Pick...

(phosphatase 2A protein)-leucine-carboxy methyltransferase (EC 2.1.1.233, leucine carboxy methyltransferase-1, LCMT1) is an enzyme with systematic name...

l-Photo-leucine is a synthetic derivative of the l-leucine amino acid that is used as its natural analog and is characterized for having photo-reactivity...

\rightleftharpoons } (3R)-beta-leucine Hence, this enzyme is responsible for the conversion of L-leucine to β-leucine. This enzyme belongs to the family...

Bacterial Leucine Transporter (LeuT) is a bundled twelve alpha helix protein which belongs to the family of transporters that shuttle amino acids in and...

systematic name (phosphatase 2A protein)-leucine ester acylhydrolase catalyses the reaction [phosphatase 2A protein]-leucine methyl ester + H2O ⇌ {\displaystyle...

intermediate in the metabolism of the branched-chain amino acids, which include leucine, isoleucine, and valine. Its immediate precursors are β-methylglutaconyl-CoA...

reaction Nα-benzyloxycarbonyl-L-leucine + H2O ⇌ {\displaystyle \rightleftharpoons } benzyl alcohol + CO2 + L-leucine Thus, the two substrates of this...

Cytosolic non-specific dipeptidase (EC 3.4.13.18) also known as carnosine dipeptidase 2 is an enzyme that in humans is encoded by the CNDP2 gene. This...

Leu-proteinase, leucine-specific serine proteinase, leucine endopeptidase, spinach serine proteinase (leucine specific), spinach leucine-specific serine...

N-Acetyl-L-Leucine for the treatment of Niemann-Pick disease type C and Ataxia-Telangiectasia. Future opportunities to develop N-Acetyl-Leucine include Lewy...

Enaptin also known as nesprin-1 or synaptic nuclear envelope protein 1 (syne-1) is an actin-binding protein that in humans that is encoded by the SYNE1...