Methyl-CpG-binding domain protein 3 is a protein that in humans is encoded by the MBD3 gene. DNA methylation is the major modification of eukaryotic genomes and...
12 KB (1,402 words) - 07:11, 20 May 2024
essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in...
12 KB (1,442 words) - 19:46, 3 March 2023
deacetylation (NuRD) complex. Overexpression of Mbd3, a subunit of NuRD, inhibits induction of iPSCs. Depletion of Mbd3, on the other hand, improves reprogramming...
92 KB (10,512 words) - 19:18, 10 October 2024
ENSG00000134046 MBD Known motif – In vivo/Misc source [510] VSGKCCGGMKR MBD3 ENSG00000071655 MBD Likely sequence specific TF according to literature or...
374 KB (81 words) - 02:10, 23 September 2023
HGNC:30438 Q8IYB1 9304 MBD1 HGNC:6916 Q9UIS9 9305 MBD2 HGNC:6917 Q9UBB5 9306 MBD3 HGNC:6918 O95983 9307 MBD3L1 HGNC:15774 Q8WWY6 9308 MBD3L2 HGNC:18532 Q8NHZ7...
277 KB (17 words) - 18:41, 6 October 2024
efficiencies (up to 100% within 8 days) via optimized depletion of Gatad2a/Mbd3 core member-axis of the NuRD co-repressor complex. The latter work set the...
55 KB (5,661 words) - 06:41, 17 November 2024
cases of MeCP2, MBD1 and MBD2, preferentially to methylated CpG. In human MBD3 and SETDB1, the MBD has been shown to mediate protein-protein interactions...
5 KB (570 words) - 21:07, 4 January 2024
GATAD2B has been shown to interact with Methyl-CpG-binding domain protein 2, MBD3, RBBP7 and RBBP4. ENSG00000261992 GRCh38: Ensembl release 89: ENSG00000143614...
5 KB (615 words) - 07:12, 7 January 2024
essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in...
10 KB (1,240 words) - 11:20, 4 March 2023
metastasis-associated proteins MTA1 (or MTA2 / MTA3), the methyl-CpG-binding domain protein MBD3 (or MBD2) and the chromodomain-helicase-DNA-binding protein CHD3 (aka Mi-2alpha)...
9 KB (1,104 words) - 01:15, 11 December 2024
drug resistant tumors. Aurora A kinase has been shown to interact with: MBD3, MYCN, NME1, P53, TACC1, TPX2, and UBE2N. GRCh38: Ensembl release 89: ENSG00000087586...
22 KB (2,764 words) - 06:39, 6 May 2024
S2CID 10983932. Tatematsu KI, Yamazaki T, Ishikawa F (August 2000). "MBD2-MBD3 complex binds to hemi-methylated DNA and forms a complex containing DNMT1...
19 KB (2,381 words) - 11:49, 28 March 2024
DPEP3 Identifiers Aliases DPEP3, MBD3, dipeptidase 3 External IDs OMIM: 609926; MGI: 1919104; HomoloGene: 23357; GeneCards: DPEP3; OMA:DPEP3 - orthologs...
3 KB (429 words) - 06:28, 28 March 2024
deacetylase 2, Homeobox protein TGIF1, Host cell factor C1, IFRD1, IKZF1, ING1, MBD3, MIER1, MLL, MTA1, MTA2, Mad1, Mdm2, Methyl-CpG-binding domain protein 2...
50 KB (5,476 words) - 01:27, 4 January 2024
essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 (this gene) comprise a family of nuclear proteins related by the...
18 KB (2,301 words) - 10:35, 24 December 2023
Saito M, Ishikawa F (September 2002). "The mCpG-binding domain of human MBD3 does not bind to mCpG but interacts with NuRD/Mi2 components HDAC1 and MTA2"...
15 KB (1,841 words) - 02:43, 29 November 2023
PMID 11788710. Saito M, Ishikawa F (2002). "The mCpG-binding domain of human MBD3 does not bind to mCpG but interacts with NuRD/Mi2 components HDAC1 and MTA2"...
13 KB (1,452 words) - 01:27, 11 April 2024
Saito M, Ishikawa F (September 2002). "The mCpG-binding domain of human MBD3 does not bind to mCpG but interacts with NuRD/Mi2 components HDAC1 and MTA2"...
13 KB (1,474 words) - 01:41, 26 March 2024
CLOCK-BMAL1 complex. MTA2 has been shown to interact with: CHD4, HDAC1, HDAC2, MBD3 MTA1, RBBP4, RBBP7, and SATB1. GRCh38: Ensembl release 89: ENSG00000149480...
17 KB (2,067 words) - 12:43, 24 December 2023
PMID 11384103. Saito M, Ishikawa F (2002). "The mCpG-binding domain of human MBD3 does not bind to mCpG but interacts with NuRD/Mi2 components HDAC1 and MTA2"...
12 KB (1,367 words) - 01:10, 29 March 2024
new family of potent transcriptional repressors interacting with MBD2 and MBD3". The Journal of Biological Chemistry. 277 (43): 40958–40966. doi:10.1074/jbc...
41 KB (4,587 words) - 20:20, 3 December 2023
metastasis-associated proteins (MTA), methyl-CpG-binding domain proteins (MBD2 or MBD3), and histone deacetylases (HDAC1 and HDAC2). This association allows SALL4...
36 KB (4,631 words) - 22:52, 27 March 2024