Mucin short variant S1 (redirect from MUC1 (gene))
mucin (PEM) or epithelial membrane antigen (EMA), is a mucin encoded by the MUC1 gene in humans. Mucin short variant S1 is a glycoprotein with extensive O-linked...
25 KB (2,926 words) - 10:12, 3 December 2023
part of the immune system. Overexpression of the mucin proteins, especially MUC1, is associated with many types of cancer. Although some mucins are membrane-bound...
22 KB (2,313 words) - 02:13, 27 October 2024
humans by the MUC1 gene. It is cleaved into two chains: mucin-1 subunit alpha (MUC1-NT; MUC1-alpha) and mucin-1 subunit beta (MUC-CT; MUC1-beta). These...
16 KB (2,030 words) - 06:40, 11 November 2024
research groups have proposed that MUC1, a member of the mucin family of glycosylated proteins, is involved. MUC1 is a transmembrane glycoprotein expressed...
51 KB (5,914 words) - 21:10, 16 August 2024
disease (MKD) is caused by a mutation in the MUC1 gene. This mutation alters the genetic sequence in the MUC1 gene, resulting in a new, mutated protein,...
21 KB (2,119 words) - 23:55, 13 August 2024
derived from MUC1. CA 15-3 and associated CA 27-29 are different epitopes on the same protein antigen product of the breast cancer-associated MUC1 gene. Elevated...
2 KB (275 words) - 19:38, 30 June 2024
rise to more type I and II alveolar cells when the lung tissue is damaged. MUC1, a human gene associated with type II pneumocytes, has been identified as...
28 KB (3,215 words) - 06:37, 20 December 2024
been shown to interact with: CTNNB1, DLG4, Erbin, GRB2, HSP90AA1, IL6ST, MUC1, PICK1 and PIK3R2, PLCG1, and SHC1. SkBr3 Cell Line, over-expresses HER2...
43 KB (4,657 words) - 07:27, 28 November 2024
CBL, CBLB, CBLC, CD44, CDC25A, CRK, CTNNB1, DCN, EGF, GRB14, Grb2, JAK2, MUC1, NCK1, NCK2 PKC alpha, PLCG1, PLSCR1, PTPN1, PTPN11, PTPN6, PTPRK, SH2D3A...
60 KB (6,879 words) - 14:26, 16 July 2024
adenocarcinoma (PDAC) 90% Glands and desmoplasia Aberrant p53 SMAD4 loss MUC1 MSLN CA19-9 p53 SMAD4 KRAS p16 Pancreatic acinar cell carcinoma (ACC) 1%...
122 KB (12,842 words) - 09:00, 11 November 2024
property of MUC16 is its large size. MUC16 is more than twice as long as MUC1 and MUC4 and contains about 22,000 amino acids, making it the largest membrane-associated...
16 KB (1,916 words) - 18:26, 3 December 2023
Mucin CD43 CD164 MUC1 MUC2 MUC3A MUC3B MUC4 MUC5AC MUC5B MUC6 MUC7 MUC8 MUC12 MUC13 MUC15 MUC16 MUC17 MUC19 MUC20 Other Haptoglobin Intrinsic factor Orosomucoid...
36 KB (4,018 words) - 18:24, 24 September 2024
ovarian, colorectal, and non-small lung cell cancers and include antigens from MUC1, IDO1 (Indoleamine 2,3-dioxygenase), CTAG1B, and two VEGF receptors, FLT1...
28 KB (3,224 words) - 22:21, 24 December 2024
the airways. A unique umbilical cord lining epithelial stem cell expresses MUC1, termed (CLEC-muc). This has been shown to have good potential in the regeneration...
29 KB (3,375 words) - 07:23, 10 December 2024
Mucin CD43 CD164 MUC1 MUC2 MUC3A MUC3B MUC4 MUC5AC MUC5B MUC6 MUC7 MUC8 MUC12 MUC13 MUC15 MUC16 MUC17 MUC19 MUC20 Other Haptoglobin Intrinsic factor Orosomucoid...
28 KB (2,653 words) - 04:14, 23 July 2024
FHL2, GSK3B, HER2/neu, HNF4A, IKK2, LEF1 including transgenically, MAGI1, MUC1, NR5A1, PCAF, PHF17, Plakoglobin, PTPN14, PTPRF, PTPRK (PTPkappa), PTPRT...
107 KB (12,347 words) - 05:01, 2 November 2024
drug candidate suffered a lack of success in patient recruitment, with its MUC1 antigen-specific cancer immunotherapy drug, tecemotide (L-BLP25), missing...
48 KB (4,737 words) - 15:31, 2 December 2024
designed to induce a cellular immune response to cancer cells that express MUC1, a glycoprotein antigen that is widely over-expressed on common cancers such...
29 KB (1,701 words) - 19:34, 22 September 2024
leukapheresis. The antigen in this case is MUC1, known to be overexpressed on a variety of cancer cells and in CVac MUC1 is conjugated to the carbohydrate mannan...
6 KB (656 words) - 07:02, 7 November 2023
(June 2008). "Reference intervals for carcinoembryonic antigen (CEA), CA125, MUC1, Alfa-foeto-protein (AFP), neuron-specific enolase (NSE) and CA19.9 from...
108 KB (6,105 words) - 10:44, 2 July 2024
27.29 is a tumor marker for breast cancer. It is a form of glycoprotein MUC1. "Definition of CA 27-29. From MedicineNet. Last Editorial Review: 6/14/2012"...
920 bytes (80 words) - 05:27, 4 November 2023
targets CD20 (98.3%), CD22 (88.3%), CD40 (83.3%), CD52 (77.4%), IgM (83.3%), MUC1 core protein (57.8%), and 1D10 (50%). Symptoms including blurring or loss...
59 KB (5,773 words) - 01:40, 24 October 2024
Mucin CD43 CD164 MUC1 MUC2 MUC3A MUC3B MUC4 MUC5AC MUC5B MUC6 MUC7 MUC8 MUC12 MUC13 MUC15 MUC16 MUC17 MUC19 MUC20 Other Haptoglobin Intrinsic factor Orosomucoid...
13 KB (1,453 words) - 04:02, 10 March 2024
located within the 11p15 chromosomal locus of chromosome 11. MUC6, along with MUC1, is expressed in normal pancreases. ENSG00000277281, ENSG00000184956, ENSG00000277518...
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1990s using first generation CARs targeting a solid tumor antigens such as MUC1 did not show long-term persistence of the transferred T cells or result in...
89 KB (9,199 words) - 08:31, 31 December 2024
Illinois University Edwardsville, Edwardsville, Illinois, United States MUC1, Mucin 1, a protein Metastatic urothelial carcinoma, a type of cancer Mixed...
2 KB (234 words) - 18:09, 12 March 2023
Mucin CD43 CD164 MUC1 MUC2 MUC3A MUC3B MUC4 MUC5AC MUC5B MUC6 MUC7 MUC8 MUC12 MUC13 MUC15 MUC16 MUC17 MUC19 MUC20 Other Haptoglobin Intrinsic factor Orosomucoid...
17 KB (1,983 words) - 19:38, 30 June 2024
Mucin CD43 CD164 MUC1 MUC2 MUC3A MUC3B MUC4 MUC5AC MUC5B MUC6 MUC7 MUC8 MUC12 MUC13 MUC15 MUC16 MUC17 MUC19 MUC20 Other Haptoglobin Intrinsic factor Orosomucoid...
8 KB (835 words) - 16:01, 3 December 2023
Mucin CD43 CD164 MUC1 MUC2 MUC3A MUC3B MUC4 MUC5AC MUC5B MUC6 MUC7 MUC8 MUC12 MUC13 MUC15 MUC16 MUC17 MUC19 MUC20 Other Haptoglobin Intrinsic factor Orosomucoid...
26 KB (2,908 words) - 20:39, 21 November 2024
cytolytic target. CD227 MUC1 - Mucin 1, cell surface associated or polymorphic epithelial mucin (PEM) is a mucin encoded by the MUC1 gene in humans. The protein...
96 KB (492 words) - 06:06, 25 November 2024