• Thumbnail for Megakaryocyte
    A megakaryocyte (mega- + karyo- + -cyte, "large-nucleus cell") is a large bone marrow cell with a lobated nucleus that produces blood platelets (thrombocytes)...
    16 KB (1,787 words) - 17:27, 22 February 2024
  • Thumbnail for Thrombopoietin
    Thrombopoietin (THPO) also known as megakaryocyte growth and development factor (MGDF) is a protein that in humans is encoded by the THPO gene. Thrombopoietin...
    9 KB (1,066 words) - 13:45, 13 August 2023
  • Thumbnail for Megakaryocyte–erythroid progenitor cell
    Megakaryocyte–erythroid progenitor cells (MEPs), among other blood cells, are generated as a result of hematopoiesis, which occurs in the bone marrow...
    3 KB (293 words) - 07:53, 14 June 2024
  • Thumbnail for Thrombopoiesis
    expansion of hematopoietic stem cells, stimulating the increase of megakaryocyte progenitor cells, and supporting these cells so they mature to become...
    5 KB (595 words) - 18:55, 18 May 2024
  • former online music market CFU-GEMM, granulocyte-erythrocyte-monocyte-megakaryocyte colony forming unit Gem (disambiguation) This disambiguation page lists...
    399 bytes (74 words) - 18:40, 11 December 2019
  • Thumbnail for Platelet
    have no cell nucleus; they are fragments of cytoplasm derived from the megakaryocytes of the bone marrow or lung, which then enter the circulation. Platelets...
    70 KB (8,414 words) - 23:19, 8 July 2024
  • Thumbnail for Haematopoiesis
    lymphopoiesis. Cells of the myeloid lineage, which include granulocytes, megakaryocytes, monocytes, and macrophages, are derived from common myeloid progenitors...
    32 KB (3,345 words) - 09:02, 27 March 2024
  • Thumbnail for Nail clubbing
    Increased entry of megakaryocytes into the systemic circulation. Under normal circumstances in healthy individuals, megakaryocytes that arise from the...
    13 KB (1,354 words) - 14:41, 20 March 2024
  • Thumbnail for Megakaryocyte-associated tyrosine kinase
    Megakaryocyte-associated tyrosine-protein kinase is an enzyme that in humans is encoded by the MATK gene. The protein encoded by this gene has amino acid...
    9 KB (1,177 words) - 01:33, 17 April 2022
  • production of blood cells such as erythrocytes (red cells), granulocytes and megakaryocytes, the latter cells responsible for the production of platelets. Signs...
    27 KB (2,843 words) - 09:38, 11 June 2024
  • Thumbnail for Essential thrombocythemia
    characterised by the overproduction of platelets (thrombocytes) by megakaryocytes in the bone marrow. It may, albeit rarely, develop into acute myeloid...
    19 KB (2,159 words) - 09:04, 3 July 2024
  • Thumbnail for Emperipolesis
    inside a megakaryocyte (Wright-Giemsa, 100x, oil). Emperipolesis in Rosai-Dorfman disease highlighted by S-100 staining. Emperipolesis: Megakaryocyte containing...
    4 KB (380 words) - 23:57, 3 July 2023
  • Thumbnail for POEMS syndrome
    be normal. Other common findings were megakaryocyte hyperplasia and clustering, as well as unusual megakaryocyte appearances. Atypical plasma cells invade...
    25 KB (2,241 words) - 11:16, 15 July 2024
  • Thumbnail for Myelodysplastic syndrome
    features in platelet producing megakaryocytes (lack of lobation) Hypersegmented (osteoclastic appearing) megakaryocytes Ballooning of the platelets (seen...
    59 KB (6,328 words) - 03:01, 1 July 2024
  • proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production...
    12 KB (1,474 words) - 23:29, 2 July 2024
  • Thumbnail for Hematopoietic stem cell
    macrophages, neutrophils, basophils, eosinophils, erythrocytes, and megakaryocytes to platelets. Lymphoid cells include T cells, B cells, natural killer...
    38 KB (4,500 words) - 21:21, 1 July 2024
  • Thumbnail for Chromosome 5q deletion syndrome
    macrocytic anemia, often a moderate thrombocytosis, erythroblastopenia, megakaryocyte hyperplasia with nuclear hypolobation, and an isolated interstitial...
    7 KB (639 words) - 21:57, 22 June 2024
  • Thumbnail for Amber Lee Connors
    Hanebado!, Pieck from Attack on Titan, Lucinia Porter from Meta Runner, Megakaryocyte from Cells at Work!, Mei Aihara from Citrus, and Furina / Focalors from...
    54 KB (3,709 words) - 04:04, 22 June 2024
  • Thumbnail for Neutrophil
    Baso-E=basophilic erythroblast, poly-e=polychromatic erythroblast, ortho-E=orthochromatic erythroblast, erythrocyte, promegakaryocyte, megakaryocyte, platelet...
    53 KB (5,672 words) - 23:32, 14 July 2024
  • Thumbnail for Promegakaryocyte
    a precursor cell for a megakaryocyte. It arises from a megakaryoblast, into a promegakaryocyte and then into a megakaryocyte, which will eventually break...
    4 KB (416 words) - 10:16, 4 May 2024
  • and entry into S-phase. The induction of endomitosis in mammalian megakaryocytes involves activation of the c-mpl receptor by the thrombopoietin (TPO)...
    29 KB (2,989 words) - 22:31, 28 February 2024
  • Thumbnail for Immune thrombocytopenic purpura
    cells in the liver. The IgG autoantibodies are also thought to damage megakaryocytes, the precursor cells to platelets, although this is believed to contribute...
    48 KB (5,426 words) - 13:16, 23 June 2024
  • Thumbnail for White blood cell
    Baso-E=Basophilic erythroblast, poly-E=Polychromatic erythroblast, Ortho-E=Orthochromatic erythroblast, Erythrocyte, Promegakaryocyte, Megakaryocyte, Platelet...
    32 KB (3,210 words) - 09:17, 4 June 2024
  • Thumbnail for Nuclear–cytoplasmic ratio
    decreases. For example, "blast" forms of erythrocytes, leukocytes, and megakaryocytes start with an N:C ratio of 4:1, which decreases as they mature to 2:1...
    2 KB (253 words) - 09:19, 7 February 2024
  • Thumbnail for Megakaryoblast
    thrombopoiesis, the promegakaryocyte matures into the form of a megakaryocyte. From the megakaryocyte, platelets are formed. The megakaryoblast is the beginning...
    7 KB (745 words) - 13:10, 25 May 2024
  • Thumbnail for Polyploidy
    Pfitzer P, Schneider W (December 1987). "Significance of polyploidy in megakaryocytes and other cells in health and tumor disease". Klinische Wochenschrift...
    81 KB (8,829 words) - 02:44, 15 July 2024
  • cell regeneration. It is a colony-stimulating factor that stimulates megakaryocyte production. It functions by stimulating ligands for interleukin 3 and...
    2 KB (181 words) - 22:46, 7 November 2023
  • Thumbnail for Mesothelin
    glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF). Although it has been proposed that mesothelin...
    24 KB (2,787 words) - 19:53, 13 July 2024
  • Thumbnail for Bone marrow
    6% 17.9–29.2 Orthochromatic normoblast 2.0% 0.4–4.6 Other cell types Megakaryocytes < 0.1% 0.0-0.4 Plasma cells 1.3% 0.4-3.9 Reticular cells 0.3% 0.0-0...
    34 KB (3,634 words) - 13:56, 17 June 2024
  • viruses. Macrophages remove senescent erythrocytes, leukocytes, and megakaryocytes by phagocytosis and digestion. Formation of new red blood cells (RBCs)...
    5 KB (463 words) - 23:33, 4 July 2024