• Thumbnail for Monoacylglycerol lipase
    Monoacylglycerol lipase (EC 3.1.1.23; systematic name glycerol-ester acylhydrolase, also known as MAG lipase, acylglycerol lipase, MAGL, MGL or MGLL)...
    10 KB (965 words) - 16:01, 9 August 2024
  • Thumbnail for Lipoprotein lipase
    Lipoprotein lipase (LPL) (EC 3.1.1.34, systematic name triacylglycerol acylhydrolase (lipoprotein-dependent)) is a member of the lipase gene family, which...
    33 KB (4,021 words) - 02:22, 3 July 2024
  • Thumbnail for Lipolysis
    hydrolysis of diacylglycerol to monoacylglycerol and monoacylglycerol lipase (MGL) catalyzes the hydrolysis of monoacylglycerol to glycerol. Perilipin 1A is...
    15 KB (1,555 words) - 16:37, 17 August 2024
  • Thumbnail for Triacylglycerol lipase
    hepatic lipase, amano CES, amano B, tributyrase, triglyceride lipase, liver lipase, hepatic monoacylglycerol acyltransferase). Pancreatic lipase Gastric...
    4 KB (369 words) - 16:05, 26 August 2023
  • Thumbnail for Hormone-sensitive lipase
    Hormone-sensitive lipase (EC 3.1.1.79, HSL), also previously known as cholesteryl ester hydrolase (CEH), sometimes referred to as triacylglycerol lipase, is an enzyme...
    16 KB (1,904 words) - 05:17, 5 May 2024
  • Thumbnail for Diacylglycerol lipase
    Diacylglycerol lipase, also known as DAG lipase, DAGL, or DGL, is an enzyme that catalyzes the hydrolysis of diacylglycerol, releasing a free fatty acid...
    23 KB (2,148 words) - 00:29, 31 August 2023
  • Thumbnail for Endocannabinoid system
    the endocannabinoids, including fatty acid amide hydrolase and monoacylglycerol lipase. The cannabinoid receptors CB1 and CB2, two G protein-coupled receptors...
    68 KB (7,780 words) - 04:56, 19 September 2024
  • Thumbnail for Monoglyceride
    hydrolysis of triglycerides by lipoprotein lipase and the enzymatic hydrolysis of diglycerides by diacylglycerol lipase; or as an intermediate in the alkanoylation...
    6 KB (602 words) - 17:26, 11 July 2024
  • lipases, including hormone sensitive lipase, monoacylglycerol lipase, adipose triglyceride lipase, and diacylglycerol lipase Cholinesterases, including acetylcholinesterase...
    3 KB (351 words) - 14:14, 19 March 2023
  • Thumbnail for Neuromodulation
    Hashimotodani Y, Ohno-Shosaku T, Kano M (January 2007). "Presynaptic monoacylglycerol lipase activity determines basal endocannabinoid tone and terminates retrograde...
    32 KB (2,945 words) - 16:11, 26 October 2024
  • of ATGL and HSL liberates the first two fatty acids. Cellular monoacylglycerol lipase (MGL), liberates the final fatty acid. The remaining glycerol enters...
    22 KB (2,795 words) - 20:59, 23 July 2024
  • Thumbnail for Exoenzyme
    molecule of monoacylglycerol. LPL can be found in endothelial cells in fatty tissues, such as adipose, cardiac, and muscle. Lipoprotein lipase is downregulated...
    29 KB (3,326 words) - 21:43, 24 September 2024
  • Thumbnail for Cannabigerol
    research has found that CBG does inhibit FAAH and DGL, as well as monoacylglycerol lipase (MAGL), although it is less potent as an inhibitor of FAAH than...
    24 KB (1,932 words) - 19:17, 22 September 2024
  • Thumbnail for 2-Oleoylglycerol
    metabolized to oleic acid and glycerol primarily by the enzyme monoacylglycerol lipase (MAGL). In 2011, 2OG was found to be an endogenous ligand to GPR119...
    4 KB (253 words) - 16:22, 15 July 2024
  • endocannabinoid mainly metabolized by a different enzyme called monoacylglycerol lipase (MAGL) rather than by FAAH, were largely unchanged relative to...
    25 KB (2,462 words) - 18:27, 28 October 2024
  • Thumbnail for Pancreatic lipase family
    Triglyceride lipases (EC 3.1.1.3) are a family of lipolytic enzymes that hydrolyse ester linkages of triglycerides. Lipases are widely distributed in animals...
    14 KB (1,644 words) - 19:26, 13 September 2023
  • Thumbnail for Fatty-acid amide hydrolase 1
    amidohydrolase". Endocannabinoid enhancer Endocannabinoid reuptake inhibitor Monoacylglycerol lipase GRCh38: Ensembl release 89: ENSG00000117480 – Ensembl, May 2017...
    33 KB (3,460 words) - 01:21, 16 August 2024
  • Thumbnail for 2-Arachidonoylglycerol
    CB1 receptor-dependent mechanism. 2-AG is hydrolyzed in vitro by monoacylglycerol lipase (MAGL), fatty acid amide hydrolase (FAAH), and the uncharacterized...
    14 KB (1,410 words) - 22:58, 15 July 2023
  • Laws of Massachusetts, also known as Massachusetts General Laws Monoacylglycerol lipase, a human protein Multiple grenade launcher, such as the Milkor...
    548 bytes (100 words) - 12:35, 21 April 2020
  • Thumbnail for JZL184
    JZL184 is an irreversible inhibitor for monoacylglycerol lipase (MAGL), the primary enzyme responsible for degrading the endocannabinoid 2-arachidonoylglycerol...
    3 KB (137 words) - 10:21, 30 September 2024
  • Thumbnail for ABHD12
    2-AG hydrolysis. Together, ABHD12 along with two other enzymes, monoacylglycerol lipase (MAGL) and ABHD6, control 99% of 2-AG hydrolysis in the brain....
    15 KB (1,593 words) - 01:43, 11 December 2023
  • Thumbnail for URB602
    cannabinoid ligand) in rat brain presumably by inhibiting the enzyme monoacylglycerol lipase (MAGL), which is the primary metabolic enzyme of 2-AG. However...
    4 KB (249 words) - 02:50, 2 December 2022
  • 00130. PMC 3671288. PMID 23760108. Deng H, Li W (April 2020). "Monoacylglycerol lipase inhibitors: modulators for lipid metabolism in cancer malignancy...
    4 KB (523 words) - 17:16, 9 October 2024
  • Thumbnail for URB754
    by Piomelli et al. to be a potent, noncompetitive inhibitor of monoacylglycerol lipase (MGL). However, recent studies have shown that URB754 failed to...
    4 KB (230 words) - 23:48, 12 December 2021
  • of eCBEs include fatty acid amide hydrolase (FAAH) inhibitors, monoacylglycerol lipase (MAGL) inhibitors, and endocannabinoid transporter (eCBT) inhibitors...
    4 KB (357 words) - 01:58, 28 March 2024
  • Tivanisiran (SYL-1001) – TRPV1 antagonist ABX-1431 – selective monoacylglycerol lipase inhibitor Cannabidiol (CBD) – cannabinoid receptor modulator Cannabidivarin...
    23 KB (1,620 words) - 22:35, 30 October 2024
  • Thumbnail for JZL195
    potent inhibitor of both fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL), the primary enzymes responsible for degrading the endocannabinoids...
    2 KB (107 words) - 10:21, 30 September 2024
  • Thumbnail for Daniel Nomura
    Research in La Jolla, California. There he discovered a role for monoacylglycerol lipase in generating oncogenic signaling lipids that promote cancer and...
    13 KB (1,161 words) - 00:36, 7 August 2024
  • Thumbnail for ABHD6
    alpha/beta-Hydrolase domain containing 6 (ABHD6), also known as monoacylglycerol lipase ABHD6 or 2-arachidonoylglycerol hydrolase is an enzyme that in...
    3 KB (413 words) - 09:28, 7 March 2022
  • Thumbnail for Lipoprotein
    contained in the chyme, then pancreatic lipase cleaves triglyceride molecules into two fatty acids and one 2-monoacylglycerol. Enterocytes readily absorb the...
    23 KB (2,599 words) - 18:32, 30 July 2024