Homeobox protein Nkx-2.2 is a protein that in humans is encoded by the NKX2-2 gene. Homeobox protein Nkx-2.2 contains a homeobox domain and may be involved...

Homeobox protein Nkx-2.5 is a protein that in humans is encoded by the NKX2-5 gene. Homeobox-containing genes play critical roles in regulating tissue-specific...

6p25.1, 10q21.3, 15q15.1, 20p11.22 and 20p11.23. The latter locus is near NKX2-2, a highly overexpressed gene in Ewing sarcoma. EWS/FLI functions as the...

switching off Olig2 and turning on Nkx2.2, creating a sharp boundary between the cells expressing the transcription factor Nkx2.2 ventral to the cells expressing...

Nkx2-2as (Nkx2-2 antisense) is a long non-coding RNA. It is located in the cytoplasm of the cell. Nkx2-2as is involved in Neural development. Overexpression...

VENTX; Nkx: NKX2-1, NKX2-4; NKX2-2, NKX2-8; NKX3-1, NKX3-2; NKX2-3, NKX2-5, NKX2-6; HMX1, HMX2, HMX3; NKX6-1; NKX6-2; NKX6-3; Grouped as Lmx 1/5, 2/9, 3/4...

NKX-homeodomain factors include: NKX1-1, NKX1-2 NKX2-1, NKX2-2, NKX2-4, NKX2-8 NKX3-1, NKX3-2 NKX6-1, NKX6-2, NKX6-3 Stanfel MN, Moses KA, Schwartz RJ, Zimmer...

and give rise to multiple cell lineages. Pancreatic progenitor cells are Nkx2.2+/Nkx6.1+/P48+ cells. Endocrine progenitor cells develop from Pancreatic...

is downregulated and Nkx2.2, which inhibits proneural genes, is upregulated. Glial fate switch was reduced by inhibiting Nkx2.2 and Olig2 in neural progenitors...

NK2 homeobox 1 (NKX2-1), also known as thyroid transcription factor 1 (TTF-1), is a protein which in humans is encoded by the NKX2-1 gene. Thyroid transcription...

Neuroscience Research 2: 17–28. The bHLH Transcription factor Olig2 promotes oligodendrocyte differentiation in collaboration with Nkx2.2. Zhou, Q. *, Choi...

Loomis Z, Pugh-Bernard A, Schrunk J, Doyle MJ, Minic A, McCoy E, Sussel L. Nkx2.2 regulates cell fate choice in the enteroendocrine cell lineages of the intestine...

Jose M.; Ericson, Johan; Arnold, Hans-Henning; Holz, Andreas (2015). "Nkx2.2 and Nkx2.9 Are the Key Regulators to Determine Cell Fate of Branchial and Visceral...

ghrelin-producing cells. Before further investigation took place, it was thought that Nkx2.2 and Pax4 genes promote cell differentiation of β-cells, but in their absence...

1/Nkx6.2 coordinate expression of Olig1 and Olig2 in neuroepithelial cells of the pMN and p3 domains of the ventral ventricular zone. Together, Nkx2.2 and...

Similarly, variations in the transcription factors GLIS3, NEUROD1, NEUROG3, NKX2-2, or MNX1 can result in malformed or absent β cells that do not secrete insulin...

in the Wnt-β-Catenin Pathway, most likely in inhibiting remyelination. NKX2-2 is a gene coding for a protein that may increase the number of OPCs in low...

009. PMID 15993959. Raum JC, Gerrish K, Artner I, et al. (2006). "FoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved...

vitro [614] RAGDR NKX2-2 ENSG00000125820 Homeodomain Known motif – from protein with 100% identical DBD – in vitro [615] RAGDR NKX2-3 ENSG00000119919...

K, Li H, Qi Y, Cao Q, et al. (March 2010). "Co-localization of Nkx6.2 and Nkx2.2 homeodomain proteins in differentiated myelinating oligodendrocytes"...

Q15270 10577 NKX1-2 HGNC:31652 Q9UD57 10578 NKX2-1 HGNC:11825 P43699 10579 NKX2-2 HGNC:7835 O95096 10580 NKX2-3 HGNC:7836 Q8TAU0 10581 NKX2-4 HGNC:7837 Q9H2Z4...

DH, Stiles CD (Oct 2003). "Cross-repressive interaction of the Olig2 and Nkx2.2 transcription factors in developing neural tube associated with formation...

Homeobox protein Nkx-2.3 is a protein that in humans is encoded by the NKX2-3 gene. NKX2C is a member of the NKX family of homeodomain-containing transcription...

NKX2-5 also interacts with MYH6. Mutations of all these proteins are associated with both atrial and ventricular septal defects; In addition, NKX2-5...

morphogen gradient into transcriptional events, and is directly regulated by NKX2-2. The Irx3 gene controls the subdivision of the neural territory by working...

an autosomal dominant pattern. This gene is also known as NK2 homeobox 1 (NKX2-1) The single-nucleotide substitution mutation then ultimately has drastic...

newborn screening programs is to detect and start treatment within the first 1–2 weeks of life. Treatment consists of a daily dose of thyroxine, available...

diabetes: mutations in the coding region of the BETA2/NeuroD1 (NEUROD1) and Nkx2.2 (NKX2B) genes are not associated with maturity-onset diabetes of the young...

transcription factor first isolated in Drosophila flies. The human homolog is the Nkx2-5 gene. tinman is expressed in the precardiac mesoderm and is responsible...

the JAG1 gene can lead to abnormal heart development associated with TOF. NKX2-5 codes for cardiac morphogenesis regulators to allow for proper heart development...