Hepatitis C virus nonstructural protein 4A (redirect from NS4A)
Nonstructural protein 4A (NS4A) is a viral protein found in the hepatitis C virus. It acts as a cofactor for the enzyme NS3. Beld M, Penning M, van Putten...
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Dengue virus (section NS4A protein)
structural (C, E, prM) and seven non-structural proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B, NS5). All non-structural proteins are necessary to together create...
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[citation needed] Nonstructural proteins consist of NS1, NS2A, NS2B, NS3, NS4A, NS4B, and NS5. These proteins mainly assist with viral replication or act...
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dengue virus polyprotein at the NS3/NS4A and NS4B/NS5 junctions is mediated by viral protease NS2B-NS3, whereas NS4A/NS4B may be processed by a cellular...
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forms a heterodimeric complex with NS4A—a 54 amino acid membrane protein that acts as a cofactor of the proteinase. NS4A—a 54 amino acid membrane protein...
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Glecaprevir/pibrentasvir Combination of Glecaprevir NS3/NS4A inhibitor Pibrentasvir NS5A inhibitor Clinical data Trade names Mavyret, Maviret, others AHFS/Drugs...
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responsible for viral replication and include the following three classes: NS3 and NS4A protease inhibitors, including telaprevir, boceprevir, simeprevir, and others...
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antigens have been found in infected cell nuclei. The viral protein numbered NS4A can lead to small head size (microcephaly) because it disrupts brain growth...
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infection. A complex known as NS2-NS3/NS4A (NS2-3/4A) is created when NS4A joins with uncleaved NS2-NS3 (NS2-3) or NS3/NS4A. It can be utilized to support RNA...
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protein (E). The seven nonstructural proteins are: NS1, NS2A, NS2B, NS3, NS4A, NS4B, and NS5. The role of some nonstructural proteins is known, NS5 serves...
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two viral proteins found in hepatitis C virus: NS4A NS4B Dengue virus NS4a and NS4b West Nile virus NS4A and NS4B New Shepard 4, a Blue Origin reusable...
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structural (C, prM, E) and seven nonstructural proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B, NS5); the enumeration corresponds to the arrangement of the protein...
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and Envelope) and seven non-structural proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B, NS5). The genomic RNA is modified at the 5′ end of positive-strand...
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Alanine is found at position P1' of the NS4A-NS4B cleavage site, whereas serine is found at position P1' of the NS3-NS4A, NS4B-NS5A and NS5A-NS5B cleavage sites...
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structural (C, prM/M and E) and seven non-structural (NS1, NS2a, NS2b, NS3, NS4a, NS4b and NS5) proteins. The genome of KFDV is very similar (>92% homologous)...
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VSPs: viral envelope E1 E2 VNPs: P7 NS2 NS3 NS4A NS4B NS5A NS5B...
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1b and targeting the HCV antigens nonstructural protein 3 (NS3) and 4A (NS4A), as well as NS4B and NS5A proteins. Following immunization, rhesus macaques...
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disabling the transport machinery of peroxisomal membrane proteins. The HCV NS3-NS4A strain inactivates MAVS signaling by cleaving the MAVS protein directly upstream...
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flies microcephaly appears to be caused by the flavivirid virus protein NS4A, which can disrupt brain growth by hijacking a pathway which regulates growth...
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and NS4B proteins to bind IKKε and prevent IRF3 phosphorylation and its NS4A protein, as per the zika virus, to bind MAVS to block RLR receptor binding...
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encoding 3374 amino acids. The ORF has the gene order C-prM-E-NS1-NS2A-NS2B-NS3-NS4A-NS4B-NS5 which is consistent with mosquito- and tick-borne flaviviruses (Fig...
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envelope glycoproteins (E1 and E2), six nonstructural proteins (NS2, NS3, NS4A, NS4B, NS5A, and NS5B), a truncated core protein (S, nucleocapsid), and an...
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Protein G, for proteins that interact with the Dengue Virus protein DENV-2 NS4A with the SBP-Tag and the Calmodulin Tag. and for proteins that interact with...
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of the Hepatitis C Virus NS3 Protease Domain Complexed with a Synthetic NS4A Cofactor Peptide". Cell. 87 (2): 343–355. doi:10.1016/S0092-8674(00)81351-3...
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replication and assembly. These proteins are named NS1, NS2A, NS2B, NS3, NS4A, NS4B, NS5, and NS2K, where NS denotes “non-structural”. NS3 has enzymatic...
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of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide". Cell. 87 (2): 343–55. doi:10.1016/s0092-8674(00)81351-3...
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Virus NS5A Protein Depends on NS3-Mediated Autocleavage between NS3 and NS4A". Journal of Virology. 94 (19). doi:10.1128/JVI.00420-20. ISSN 1098-5514...
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encoding over 3,000 amino acid polyproteins. The AnhC, PrM, M, NS2A, NS2B, NS3, NS4A, 2K, NS4B and NS5 proteins are all of the same length. ALKV owns the largest...
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envelope (E), along with seven non-structural proteins (NS1, NS2A, NS2B, NS3, NS4A, 2K, NS4B, and NS5). The SPONV capsid is icosahedral and the similar to other...
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envelope (E). The non-structural proteins include NS1, NS2A, NS2B, NS3, NS4A, 2K, NS4B, and NS5. Protein 2K is not found in many other flaviviruses. NS3...
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