the "activation" of a fatty acid. The activation is catalyzed by palmitoyl-coenzyme A synthetase and the reaction proceeds through a two step mechanism...
7 KB (612 words) - 20:33, 15 September 2024
Coenzyme A (CoA, SHCoA, CoASH) is a coenzyme, notable for its role in the synthesis and oxidation of fatty acids, and the oxidation of pyruvate in the...
26 KB (2,528 words) - 21:25, 28 August 2024
fatty-acyl-CoA hydrolase, palmitoyl coenzyme A hydrolase, palmitoyl thioesterase, palmitoyl coenzyme A hydrolase, palmitoyl-CoA deacylase, palmityl thioesterase...
7 KB (813 words) - 02:53, 24 May 2024
ACOT4 (redirect from Acyl-coenzyme A thioesterase 4)
hydrolases, and palmitoyl-CoA hydrolases. The reaction carried out by these enzymes is as follows: CoA ester + H2O → free acid + coenzyme A These enzymes...
9 KB (1,210 words) - 13:23, 24 January 2024
1016/0006-291X(65)90116-6. Kawaguchi A, Bloch K (September 1974). "Inhibition of glucose 6-phosphate dehydrogenase by palmitoyl coenzyme A". The Journal of Biological...
23 KB (2,413 words) - 18:05, 29 August 2024
constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor also mediates the feedback regulation...
8 KB (970 words) - 11:33, 18 August 2023
acyl-CoA dehydrogenase (EC 1.3.8.8, palmitoyl-CoA dehydrogenase, palmitoyl-coenzyme A dehydrogenase, long-chain acyl-coenzyme A dehydrogenase, long-chain-acyl-CoA:(acceptor)...
4 KB (403 words) - 14:47, 26 August 2023
Carnitine palmitoyltransferase I deficiency (redirect from Carnitine palmitoyl transferase 1 deficiency)
University of Washington, Seattle. PMID 20301700.update 2010 "Carnitine palmitoyl transferase 1 deficiency | Genetic and Rare Diseases Information Center...
7 KB (599 words) - 15:56, 16 October 2024
Carnitine palmitoyltransferase I (redirect from Carnitine-palmitoyl transferase I)
and CPT1B. The "A site" or "CoA site" appears to bind both malonyl-CoA and palmitoyl-CoA, as well as other molecules containing coenzyme A, suggesting that...
19 KB (2,464 words) - 00:31, 12 June 2024
Monolysocardiolipin acyltransferase (category Protein pages needing a picture)
AT-1 typically utilizes linoleoyl coenzyme A, preferred to oleoyl coenzyme A, which is preferred to palmitoyl coenzyme A. MLCL AT-1 activity increases in...
6 KB (635 words) - 17:47, 7 July 2024
(November 1972). "Regulation of the activity of acetyl coenzyme A carboxylase by palmitoyl coenzyme A and citrate". J. Biol. Chem. 247 (21): 6946–52. doi:10...
23 KB (2,740 words) - 19:59, 29 August 2024
CPT-I inhibitors: etomoxir, oxfenicine, perhexiline CPT-I (carnitine palmitoyl transferase) converts fatty acyl-CoA to fatty acyl-carnitine. Carnitine...
2 KB (164 words) - 19:24, 6 May 2024
hydrolases, and palmitoyl-CoA hydrolases. The reaction carried out by these enzymes is as follows: CoA ester + H2O → free acid + coenzyme A These enzymes...
9 KB (1,183 words) - 05:02, 8 March 2024
its normal substrate serine, but also of alanine or glycine, with palmitoyl-coenzyme A. The reactions lead to the formation of two aberrant sphingolipid...
44 KB (5,140 words) - 11:29, 3 December 2023
ACOT11 (redirect from Acyl-coenzyme A thioesterase 11)
Numa S (Aug 1978). "Inhibition of rat-liver acetyl-coenzyme-A carboxylase by palmitoyl-coenzyme A. Formation of equimolar enzyme-inhibitor complex". European...
11 KB (1,401 words) - 02:10, 9 February 2024
hydrolases, and palmitoyl-CoA hydrolases. The reaction carried out by these enzymes is as follows: CoA ester + H2O → free acid + coenzyme A These enzymes...
10 KB (1,356 words) - 13:22, 24 January 2024
MeSH D13.695.667.138.382.300.500 – malonyl coenzyme a MeSH D13.695.667.138.382.300.700 – palmitoyl coenzyme a MeSH D13.695.667.138.395 – cyclic amp MeSH D13...
42 KB (3,875 words) - 18:21, 20 June 2023
coenzyme a MeSH D08.211.211.300.075 – acetyl coenzyme a MeSH D08.211.211.300.500 – malonyl coenzyme a MeSH D08.211.211.300.700 – palmitoyl coenzyme a...
158 KB (15,232 words) - 06:41, 8 March 2024
hydrolases, and palmitoyl-CoA hydrolases. The reaction carried out by these enzymes is as follows: CoA ester + H2O → free acid + coenzyme A These enzymes...
7 KB (969 words) - 13:23, 24 January 2024
acyl-coenzyme A dehydrogenase deficiency (MCAD deficiency) Short-chain acyl-coenzyme A dehydrogenase deficiency (SCAD deficiency) 3-hydroxyacyl-coenzyme A...
9 KB (971 words) - 14:49, 10 October 2024
Acetyl-CoA carboxylase (redirect from Acetyl coenzyme A carboxylase)
feedback inhibitors of ACC. One such negative allosteric modulator is palmitoyl-CoA. Phosphorylation can result when the hormones glucagon or epinephrine...
27 KB (2,990 words) - 21:27, 4 July 2024
ACOT7 (redirect from Cytosolic acyl coenzyme A thioester hydrolase)
Cytosolic acyl coenzyme A thioester hydrolase is an enzyme that in humans is encoded by the ACOT7 gene. This gene encodes a member of the acyl coenzyme family...
5 KB (590 words) - 13:24, 24 January 2024
hydrolases, and palmitoyl-CoA hydrolases. The reaction carried out by these enzymes is as follows: CoA ester + H2O → free acid + coenzyme A These enzymes...
11 KB (1,321 words) - 06:19, 30 September 2024
Stearoyl-CoA 9-desaturase (redirect from Stearoyl coenzyme A desaturase 1)
acids (MUFAs), specifically oleate and palmitoleate from stearoyl-CoA and palmitoyl-CoA. Oleate and palmitoleate are major components of membrane phospholipids...
27 KB (3,137 words) - 21:10, 29 June 2024
hydrolases, and palmitoyl-CoA hydrolases. The reaction carried out by these enzymes is as follows: CoA ester + H2O → free acid + coenzyme A These enzymes...
19 KB (1,860 words) - 11:45, 19 September 2024
5′-phosphate, serves as a coenzyme in more than 140 enzyme reactions in amino acid, glucose, and lipid metabolism. Plants synthesize pyridoxine as a means of protection...
61 KB (6,991 words) - 15:01, 20 October 2024
in the Coenzyme A (CoA) biosynthetic pathway. It phosphorylates pantothenate (vitamin B5) to form 4'-phosphopantothenate at the expense of a molecule...
21 KB (2,484 words) - 10:09, 19 May 2024
ACOT8 (redirect from Acyl-coenzyme A thioesterase 8)
Acyl-coenzyme A thioesterase 8 is an enzyme that in humans is encoded by the ACOT8 gene. The protein encoded by this gene is a peroxisomal thioesterase...
7 KB (880 words) - 13:25, 24 January 2024
of one or more polypeptides arranged in a biologically functional way, often bound to ligands such as coenzymes and cofactors, to another protein or other...
22 KB (2,418 words) - 23:33, 30 July 2024
protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular...
10 KB (1,256 words) - 16:24, 31 July 2024