• DNA primase is an enzyme involved in the replication of DNA and is a type of RNA polymerase. Primase catalyzes the synthesis of a short RNA (or DNA in...
    20 KB (2,371 words) - 16:05, 10 July 2024
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    helix. The preinitiation complex also loads α-primase and other DNA polymerases onto the DNA. After α-primase synthesizes the first primers, the primer-template...
    60 KB (7,286 words) - 08:26, 2 July 2024
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    creating what is known as the DNA replication fork. Following this fork, DNA primase and DNA polymerase begin to act in order to create a new complementary...
    33 KB (4,435 words) - 14:24, 7 June 2024
  • helicase–primase complex (also helicase-primase, Hel/Prim, H-P or H/P) is a complex of enzymes including DNA helicase and DNA primase. A helicase-primase associated...
    3 KB (331 words) - 17:05, 27 August 2024
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    α-DNA primase complex) consists of four subunits: the catalytic subunit POLA1, the regulatory subunit POLA2, and the small and the large primase subunits...
    3 KB (338 words) - 07:55, 4 January 2024
  • DnaG is a bacterial DNA primase and is encoded by the dnaG gene. The enzyme DnaG, and any other DNA primase, synthesizes short strands of RNA known as...
    20 KB (2,544 words) - 21:09, 14 December 2022
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    Replisome (section Primase)
    proteins including helicase, RFC, PCNA, gyrase/topoisomerase, SSB/RPA, primase, DNA polymerase III, RNAse H, and DNA ligase. For prokaryotes, each dividing...
    32 KB (3,700 words) - 00:38, 1 January 2024
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    (herpes zoster). It acts as an inhibitor of the zoster virus's helicase–primase complex. Amenamevir was approved in Japan for the treatment of shingles...
    4 KB (167 words) - 19:46, 4 June 2024
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    inhibition of the viral helicase primase complex, encoded by the UL5 (helicase), UL8 (scaffold protein) and UL52 (primase) genes, which is essential for...
    10 KB (997 words) - 16:34, 11 August 2024
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    different superfamily (InterPro: IPR043519). Primases generally don't fall into either category. Bacterial primases usually have the Toprim domain, and are...
    7 KB (673 words) - 23:08, 9 July 2024
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    initiation of synthesizing a strand of DNA. A class of enzymes called primases add a complementary RNA primer to the reading template de novo on both...
    16 KB (2,112 words) - 01:32, 8 September 2024
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    DNA primase small subunit is an enzyme that in humans is encoded by the PRIM1 gene. The replication of DNA in eukaryotic cells is carried out by a complex...
    3 KB (464 words) - 19:10, 16 March 2024
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    primer, complementary to part of the single-stranded DNA, is synthesized by primase (an RNA polymerase):[citation needed] ("!" for RNA, '"$" for DNA, "*" for...
    7 KB (807 words) - 13:43, 10 December 2023
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    initiated by a short RNA segment, known as RNA primer, synthesized by Primase in the 5' to 3' direction. DNA synthesis then occurs by the addition of...
    15 KB (1,871 words) - 06:15, 30 May 2024
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    been found to cause a conformational change in Escherichia coli enzyme Primase. In this experiment Mg(OAc)2, MnCl2, CaCl2, NaOAc, LiCl, MgSO4 and MgCl2...
    9 KB (874 words) - 17:01, 8 June 2024
  • involves cloning the genes into plasmids into Escherichia coli or yeast. Primase is an RNA polymerase, and it can add a primer to an existing strand awaiting...
    11 KB (1,283 words) - 08:07, 16 July 2024
  • prior to replication. DNA synthesis is initiated by the RNA polymerase primase, which makes an RNA primer with a free 3'OH. This primer is attached to...
    61 KB (6,770 words) - 15:11, 20 August 2024
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    synthesis, polymerase α (Pol α) acts as a replicative primase. Pol α is associated with an RNA primase and this complex accomplishes the priming task by synthesizing...
    119 KB (14,646 words) - 22:02, 3 July 2024
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    DNA primase large subunit is an enzyme that in humans is encoded by the PRIM2 gene. The replication of DNA in eukaryotic cells is carried out by a complex...
    5 KB (654 words) - 12:38, 13 October 2022
  • Prokaryotic (initiation) Pre-replication complex dnaC Helicase dnaA dnaB T7 Primase dnaG Eukaryotic (preparation in G1 phase) Pre-replication complex Origin...
    6 KB (634 words) - 22:52, 2 December 2023
  • during DNA replication. The primosome consists of seven proteins: DnaG primase, DnaB helicase, DnaC helicase assistant, DnaT, PriA, Pri B, and PriC. At...
    3 KB (453 words) - 02:29, 25 March 2022
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    P89430 Virion maturation UL8 DNA helicase/primase complex-associated protein P10192 P89431 DNA virus helicase-primase complex-associated protein UL9 Replication...
    68 KB (7,305 words) - 12:36, 27 September 2024
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    replication fork machinery, including a two-subunit DNA polymerase, a Helicase-primase complex and a single-stranded DNA-binding protein. The human herpesvirus...
    10 KB (1,016 words) - 04:21, 25 August 2024
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    humans. PrimPol is a eukaryotic protein with both DNA polymerase and DNA Primase activities involved in translesion DNA synthesis. It is the first eukaryotic...
    7 KB (916 words) - 05:29, 9 June 2024
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    column. And also combinations of the above techniques. Alpha-amanitin Primase Werner F, Grohmann D (February 2011). "Evolution of multisubunit RNA polymerases...
    43 KB (5,103 words) - 08:16, 9 September 2024
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    dUTPase, ribonucleotide reductase, DNA polymerase, DNA helicase, DNA primase, and protein kinases. The B virus genome was fully sequenced in 2003 from...
    19 KB (2,150 words) - 22:30, 5 April 2024
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    helicase both unwinds the parental DNA and interacts momentarily with primase. In order for DNA replication to continue, single stranded binding proteins...
    21 KB (2,745 words) - 15:34, 29 June 2024
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    recruit the DnaB helicase, which will continue to unwind the DNA as the DnaG primase lays down an RNA primer and DNA Polymerase III holoenzyme begins elongation...
    17 KB (2,150 words) - 13:43, 23 June 2023
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    α-DNA primase complex) consists of four subunits: the catalytic subunit POLA1, the regulatory subunit POLA2, and the small and the large primase subunits...
    59 KB (7,090 words) - 06:49, 30 June 2024
  • chain of nucleotides. Therefore, replication begins as an enzyme called primase assembles an RNA primer at the origin of replication. The RNA primer consists...
    15 KB (1,619 words) - 15:23, 23 September 2023