Prostaglandin D2 (or PGD2) is a prostaglandin that binds to the receptor PTGDR (DP1), as well as CRTH2 (DP2). It is a major prostaglandin produced by...
11 KB (1,090 words) - 00:21, 17 February 2024
types of prostaglandin, including prostaglandin I2 (prostacyclin; PGI2), prostaglandin D2 (PGD2), prostaglandin E2 (PGE2), and prostaglandin F2α (PGF2α)...
24 KB (2,463 words) - 17:42, 11 July 2024
The prostaglandin D2 (PGD2) receptors are G protein-coupled receptors that bind and are activated by prostaglandin D2. Also known as PTGDR or DP receptors...
8 KB (869 words) - 11:30, 27 August 2024
glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to prostaglandin D2 (PGD2). PGD2 functions as...
11 KB (1,420 words) - 08:49, 30 January 2023
Prostaglandin E2 (PGE2), also known as dinoprostone, is a naturally occurring prostaglandin with oxytocic properties that is used as a medication. Dinoprostone...
34 KB (3,565 words) - 20:10, 14 May 2024
Cyclooxygenase (redirect from Prostaglandin-endoperoxide synthase)
Cyclooxygenase (COX), officially known as prostaglandin-endoperoxide synthase (PTGS), is an enzyme (specifically, a family of isozymes, EC 1.14.99.1)...
16 KB (1,779 words) - 11:08, 3 July 2024
Aspirin (section Prostaglandins and thromboxanes)
of Surgeons in London, showed aspirin suppressed the production of prostaglandins and thromboxanes. For this discovery he was awarded the 1982 Nobel Prize...
152 KB (16,395 words) - 02:17, 2 September 2024
12-Hydroxyheptadecatrienoic acid) Prostaglandin D2 synthase to create prostaglandin D2 Prostaglandin E synthase to create prostaglandin E2 It rearranges non-enzymatically...
6 KB (505 words) - 01:38, 1 March 2024
Prostaglandin D2 receptor 2 (DP2 or CRTH2) is a human protein encoded by the PTGDR2 gene and GPR44. DP2 has also been designated as CD294 (cluster of differentiation...
26 KB (3,216 words) - 20:42, 8 March 2024
Prostaglandin F2α (PGF2α in prostanoid nomenclature), pharmaceutically termed dinoprost is a naturally occurring prostaglandin used in medicine to induce...
12 KB (1,134 words) - 18:55, 24 April 2024
The prostaglandin D2 receptor 1 (DP1), a G protein-coupled receptor encoded by the PTGDR1 gene (also termed PTGDR), is primarily a receptor for prostaglandin...
25 KB (3,084 words) - 03:09, 10 March 2024
especially similar to selective COX-2 inhibitors. Paracetamol inhibits prostaglandin synthesis by reducing the active form of COX-1 and COX-2 enzymes. This...
123 KB (12,189 words) - 17:43, 1 September 2024
Cyclooxygenase-1 (redirect from Prostaglandin-endoperoxide synthase 1)
Cyclooxygenase 1 (COX-1), also known as prostaglandin-endoperoxide synthase 1 (HUGO PTGS1), is an enzyme that in humans is encoded by the PTGS1 gene....
18 KB (2,122 words) - 12:15, 2 June 2024
enzymes are involved in the synthesis of key biological mediators, namely prostaglandins, which are involved in inflammation, and thromboxanes, which are involved...
110 KB (11,559 words) - 22:46, 13 August 2024
administered intravenously to horses. A single dose has been shown to reduce prostaglandin E2 production and inflammatory exudate for up to 15 hours, although...
18 KB (1,686 words) - 00:29, 13 August 2024
in animal fats. It is a precursor in the formation of leukotrienes, prostaglandins, and thromboxanes. Together with omega-3 fatty acids and other omega-6...
21 KB (1,900 words) - 21:15, 28 July 2024
Prostaglandin E1 (PGE1) is a naturally occurring prostaglandin and is also used as a medication (alprostadil). In infants with congenital heart defects...
13 KB (1,105 words) - 07:16, 28 May 2024
non-selectively to block the prostaglandin synthesis by inhibition of prostaglandin G/H synthesis 1 and 2. Prostaglandin functions in the body as a messenger...
25 KB (2,264 words) - 19:45, 31 August 2024
Misoprostol (category Prostaglandins)
Misoprostol is a synthetic prostaglandin medication used to prevent and treat stomach and duodenal ulcers, induce labor, cause an abortion, and treat...
51 KB (4,767 words) - 15:29, 17 July 2024
Prostacyclin (redirect from Prostaglandin I2)
Prostacyclin (also called prostaglandin I2 or PGI2) is a prostaglandin member of the eicosanoid family of lipid molecules. It inhibits platelet activation...
20 KB (1,639 words) - 08:58, 22 December 2023
antipyretic effects. It acts by inhibiting the body's production of prostaglandin. It was patented in 1967 and approved for medical use in 1980. Ketoprofen...
18 KB (1,848 words) - 13:53, 1 July 2024
growths in the intestinal tract. Overexpression of COX-2 produces excess prostaglandins, which have been shown to increase the possibility of colorectal cancer...
42 KB (4,944 words) - 11:56, 4 April 2024
period. Like other NSAIDs, it works by inhibiting the production of prostaglandins by decreasing the activity of the enzyme cyclooxygenase (COX). Ibuprofen...
60 KB (5,878 words) - 03:22, 2 September 2024
swelling from inflammation. It works by inhibiting the production of prostaglandins, endogenous signaling molecules known to cause these symptoms. It does...
23 KB (2,294 words) - 14:58, 28 July 2024
Cyclooxygenase-2 (redirect from Prostaglandin-endoperoxide synthase 2)
Cyclooxygenase-2 (COX-2), also known as Prostaglandin-endoperoxide synthase 2 (HUGO PTGS2), is an enzyme that in humans is encoded by the PTGS2 gene....
30 KB (3,417 words) - 14:36, 15 May 2024
DP1Tooltip Prostaglandin D2 receptor 1 Agonists: Prostaglandin D2 Treprostinil Antagonists: Asapiprant Laropiprant Vidupiprant DP2Tooltip Prostaglandin D2 receptor...
95 KB (11,044 words) - 22:48, 21 August 2024
characterized by a fast onset of action. It works by blocking the production of prostaglandins (a chemical associated with pain), thereby relieving pain and inflammation...
18 KB (1,753 words) - 20:40, 17 July 2024
action by reducing the production of inflammatory mediators called prostaglandins. It is metabolized by the liver to inactive metabolites. Naproxen was...
34 KB (3,174 words) - 04:50, 18 July 2024
Prostaglandin analogues are a class of drugs that bind to a prostaglandin receptor. Wider use of prostaglandin analogues is limited by unwanted side effects...
3 KB (342 words) - 21:37, 11 July 2024
breastfeeding. Diclofenac is believed to work by decreasing the production of prostaglandins, like other drugs in this class. In 2021, diclofenac was the 61st most...
57 KB (5,575 words) - 13:25, 25 August 2024