• Thumbnail for Prostaglandin E2
    Prostaglandin E2 (PGE2), also known as dinoprostone, is a naturally occurring prostaglandin with oxytocic properties that is used as a medication. Dinoprostone...
    34 KB (3,565 words) - 20:10, 14 May 2024
  • Thumbnail for Prostaglandin
    growth. Prostaglandin E2 (PGE2) — the most abundant prostaglandin — is generated from the action of prostaglandin E synthases on prostaglandin H2 (prostaglandin...
    24 KB (2,463 words) - 17:42, 11 July 2024
  • The prostaglandin E2 (PGE2) receptors are G protein-coupled receptors that bind and are activated by prostaglandin E2. They are members of the prostaglandin...
    5 KB (509 words) - 01:31, 17 December 2023
  • Thumbnail for Prostaglandin EP2 receptor
    Prostaglandin E2 receptor 2, also known as EP2, is a prostaglandin receptor for prostaglandin E2 (PGE2) encoded by the human gene PTGER2: it is one of...
    32 KB (3,685 words) - 02:56, 10 March 2024
  • Thumbnail for Prostaglandin EP3 receptor
    Prostaglandin EP3 receptor (EP3, 53kDa), is a prostaglandin receptor for prostaglandin E2 (PGE2) encoded by the human gene PTGER3; it is one of four identified...
    38 KB (4,320 words) - 05:35, 12 August 2024
  • Thumbnail for Prostaglandin EP1 receptor
    Prostaglandin E2 receptor 1 (EP1) is a 42kDa prostaglandin receptor encoded by the PTGER1 gene. EP1 is one of four identified EP receptors, EP1, EP2, EP3...
    20 KB (2,320 words) - 00:41, 17 July 2024
  • sequence, for the insulin gene Levuglandin E2, an aldehyde Prostaglandin E2, an abortifacient Prostaglandin E2 receptor, a human gene Iodine-deficiency...
    4 KB (571 words) - 00:32, 29 July 2024
  • Thumbnail for Prostaglandin E synthase
    "Structural basis for induced formation of the inflammatory mediator prostaglandin E2". Proceedings of the National Academy of Sciences. 105 (32): 11110–11115...
    3 KB (205 words) - 15:33, 26 August 2023
  • Thumbnail for Prostaglandin EP4 receptor
    Prostaglandin E2 receptor 4 (EP4) is a prostaglandin receptor for prostaglandin E2 (PGE2) encoded by the PTGER4 gene in humans; it is one of four identified...
    40 KB (4,808 words) - 02:56, 28 March 2024
  • Thumbnail for Cyclooxygenase
    Cyclooxygenase (COX), officially known as prostaglandin-endoperoxide synthase (PTGS), is an enzyme (specifically, a family of isozymes, EC 1.14.99.1)...
    16 KB (1,779 words) - 11:08, 3 July 2024
  • Thumbnail for Aspirin
    of Surgeons in London, showed aspirin suppressed the production of prostaglandins and thromboxanes. For this discovery he was awarded the 1982 Nobel Prize...
    152 KB (16,395 words) - 02:17, 2 September 2024
  • Thumbnail for Prostaglandin F2alpha
    Prostaglandin F2α (PGF2α in prostanoid nomenclature), pharmaceutically termed dinoprost is a naturally occurring prostaglandin used in medicine to induce...
    12 KB (1,134 words) - 18:55, 24 April 2024
  • Thumbnail for Prostaglandin E
    alprostadil Prostaglandin E2 also known as dinoprostone Both types are on the World Health Organization's List of Essential Medicines. Prostaglandin E play...
    5 KB (148 words) - 21:50, 4 March 2021
  • Thumbnail for Prostaglandin E1
    Prostaglandin E1 (PGE1) is a naturally occurring prostaglandin and is also used as a medication (alprostadil). In infants with congenital heart defects...
    13 KB (1,105 words) - 07:16, 28 May 2024
  • Thumbnail for Carprofen
    administered intravenously to horses. A single dose has been shown to reduce prostaglandin E2 production and inflammatory exudate for up to 15 hours, although there...
    18 KB (1,686 words) - 00:29, 13 August 2024
  • Thumbnail for Grapiprant
    the prostaglandin EP4 receptor, one out of the four prostaglandin E2 (PGE2) receptor subgroups. The EP4 receptor then mediates the prostaglandin-E2-elicited...
    11 KB (1,033 words) - 23:56, 28 March 2024
  • of prostaglandin synthase. NSAIDs have antipyretic activity and can be used to treat fever. Fever is caused by elevated levels of prostaglandin E2 (PGE2)...
    110 KB (11,559 words) - 22:46, 13 August 2024
  • Thumbnail for Prostaglandin H2
    12-Hydroxyheptadecatrienoic acid) Prostaglandin D2 synthase to create prostaglandin D2 Prostaglandin E synthase to create prostaglandin E2 It rearranges non-enzymatically...
    6 KB (505 words) - 01:38, 1 March 2024
  • Thumbnail for Cyclooxygenase-1
    Cyclooxygenase 1 (COX-1), also known as prostaglandin-endoperoxide synthase 1 (HUGO PTGS1), is an enzyme that in humans is encoded by the PTGS1 gene....
    18 KB (2,122 words) - 12:15, 2 June 2024
  • Thumbnail for Paracetamol
    especially similar to selective COX-2 inhibitors. Paracetamol inhibits prostaglandin synthesis by reducing the active form of COX-1 and COX-2 enzymes. This...
    123 KB (12,189 words) - 17:43, 1 September 2024
  • Thumbnail for Cyclooxygenase-2
    Cyclooxygenase-2 (COX-2), also known as Prostaglandin-endoperoxide synthase 2 (HUGO PTGS2), is an enzyme that in humans is encoded by the PTGS2 gene....
    30 KB (3,417 words) - 14:36, 15 May 2024
  • Thumbnail for Prostacyclin
    Prostacyclin (also called prostaglandin I2 or PGI2) is a prostaglandin member of the eicosanoid family of lipid molecules. It inhibits platelet activation...
    20 KB (1,639 words) - 08:58, 22 December 2023
  • Thumbnail for Misoprostol
    Misoprostol (category Prostaglandins)
    Misoprostol is a synthetic prostaglandin medication used to prevent and treat stomach and duodenal ulcers, induce labor, cause an abortion, and treat...
    51 KB (4,767 words) - 15:29, 17 July 2024
  • Thumbnail for Ketorolac
    non-selectively to block the prostaglandin synthesis by inhibition of prostaglandin G/H synthesis 1 and 2. Prostaglandin functions in the body as a messenger...
    25 KB (2,264 words) - 19:45, 31 August 2024
  • Thumbnail for Naproxen
    action by reducing the production of inflammatory mediators called prostaglandins. It is metabolized by the liver to inactive metabolites. Naproxen was...
    34 KB (3,174 words) - 04:50, 18 July 2024
  • Thumbnail for Sulprostone
    Sulprostone is an analogue of prostaglandin E2 (PGE2) that has oxytocic activity in assays of rat kidney cells and tissues. There are four known receptors...
    6 KB (433 words) - 05:50, 6 May 2024
  • Thumbnail for Ketoprofen
    antipyretic effects. It acts by inhibiting the body's production of prostaglandin. It was patented in 1967 and approved for medical use in 1980. Ketoprofen...
    18 KB (1,848 words) - 13:53, 1 July 2024
  • Prostaglandin analogues are a class of drugs that bind to a prostaglandin receptor. Wider use of prostaglandin analogues is limited by unwanted side effects...
    3 KB (342 words) - 21:37, 11 July 2024
  • growths in the intestinal tract. Overexpression of COX-2 produces excess prostaglandins, which have been shown to increase the possibility of colorectal cancer...
    42 KB (4,944 words) - 11:56, 4 April 2024
  • Thumbnail for Ibuprofen
    period. Like other NSAIDs, it works by inhibiting the production of prostaglandins by decreasing the activity of the enzyme cyclooxygenase (COX). Ibuprofen...
    60 KB (5,878 words) - 03:22, 2 September 2024