• Thumbnail for Proteoglycan
    Proteoglycans are proteins that are heavily glycosylated. The basic proteoglycan unit consists of a "core protein" with one or more covalently attached...
    8 KB (835 words) - 16:01, 3 December 2023
  • Neural/glial antigen 2, or NG2, is a rat integral membrane proteoglycan found in the plasma membrane of many diverse cell types. Homologous proteins in...
    6 KB (882 words) - 01:35, 28 June 2024
  • Thumbnail for CSPG4
    Chondroitin sulfate proteoglycan 4, also known as melanoma-associated chondroitin sulfate proteoglycan (MCSP) or neuron-glial antigen 2 (NG2), is a chondroitin...
    12 KB (1,501 words) - 04:42, 25 December 2023
  • Thumbnail for Heparan sulfate
    polysaccharide found in all animal tissues. It occurs as a proteoglycan (HSPG, i.e. Heparan Sulfate ProteoGlycan) in which two or three HS chains are attached in...
    36 KB (4,151 words) - 06:37, 27 May 2024
  • Thumbnail for Proteoglycan 4
    Proteoglycan 4 or lubricin is a proteoglycan that in humans is encoded by the PRG4 gene. It acts as a joint/boundary lubricant. Lubricin is present in...
    32 KB (3,667 words) - 17:44, 10 April 2024
  • Thumbnail for Extracellular matrix
    extracellular matrix proteins to form proteoglycans (hyaluronic acid is a notable exception; see below). Proteoglycans have a net negative charge that attracts...
    36 KB (4,084 words) - 09:22, 12 August 2024
  • In enzymology, a N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase (EC 2.4.1.226) is an enzyme that catalyzes the chemical reaction...
    3 KB (309 words) - 18:17, 23 January 2024
  • Thumbnail for Cartilage
    than muscle. The matrix of cartilage is made up of glycosaminoglycans, proteoglycans, collagen fibers and, sometimes, elastin. It usually grows quicker than...
    34 KB (3,824 words) - 06:19, 27 July 2024
  • articular cartilage integrity as it is part of the proteoglycan molecules. The cartilage proteoglycan synthesis can speed up as chondroitin is going through...
    2 KB (255 words) - 19:10, 27 March 2024
  • Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase (EC 2.4.1.223, alpha-N-acetylglucosaminyltransferase I, alpha1...
    3 KB (278 words) - 18:40, 23 January 2024
  • In enzymology, a N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase (EC 2.4.1.225) is an enzyme that catalyzes the chemical reaction...
    2 KB (250 words) - 18:17, 23 January 2024
  • Thumbnail for Tendon
    including: 3% cartilage oligomeric matrix protein, 1–2% elastin, 1–5% proteoglycans, 0.2% inorganic components such as copper, manganese, and calcium. Although...
    46 KB (5,162 words) - 15:47, 20 August 2024
  • Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase (EC 2.4.1.224, alpha-N-acetylglucosaminyltransferase II...
    3 KB (355 words) - 18:40, 23 January 2024
  • Thumbnail for Tsukushi (protein)
    tsukushin is an extracellular matrix protein of the small leucine rich proteoglycan (SLRP) family. In humans it is encoded by the TSKU gene. Tsukushi is...
    2 KB (242 words) - 00:53, 4 March 2023
  • I, UDP-N-acetyl-D-galactosamine:D-glucuronyl-1,3-beta-D-galactosyl-proteoglycan beta-1,4-N-acetylgalactosaminyltransferase) is an enzyme with systematic...
    2 KB (219 words) - 18:40, 23 January 2024
  • Thumbnail for Aggrecan
    (ACAN), also known as cartilage-specific proteoglycan core protein (CSPCP) or chondroitin sulfate proteoglycan 1, is a protein that in humans is encoded...
    16 KB (1,985 words) - 03:45, 12 May 2024
  • Thumbnail for Chondroitin sulfate proteoglycan
    Chondroitin sulfate proteoglycans (CSPGs) are proteoglycans consisting of a protein core and a chondroitin sulfate side chain. They are known to be structural...
    15 KB (1,778 words) - 11:24, 12 August 2023
  • studied until recently. Like the chondroitin sulfate proteoglycans, keratan sulfate proteoglycan (KSPG) production is up regulated in reactive astrocytes...
    29 KB (3,575 words) - 10:07, 2 June 2024
  • Thumbnail for Versican
    matrix proteoglycan that is present in a variety of human tissues. It is encoded by the VCAN gene. Versican is a large chondroitin sulfate proteoglycan with...
    19 KB (2,427 words) - 15:21, 24 January 2024
  • Thumbnail for Polysulfated glycosaminoglycan
    play a role in the IL-1 degradation of proteoglycans and collagen; lysosomal enzymes that cause proteoglycans to dissociate from hyaluronic acid; elastase;...
    14 KB (1,148 words) - 18:01, 27 February 2023
  • Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase (EC 2.4.1.175, N-acetylgalactosaminyltransferase II,...
    3 KB (298 words) - 18:40, 23 January 2024
  • Thumbnail for Protein losing enteropathy
    and/or inflammation may cause epithelial matrix changes. The absence of proteoglycans, which are glycosaminoglycan chains attached to protein, may contribute...
    17 KB (1,779 words) - 23:31, 2 June 2024
  • Thumbnail for Glycosaminoglycan
    forming proteoglycans. Keratan sulfate which may modify core proteins through N-linked glycosylation or O-linked glycosylation of the proteoglycan Hyaluronic...
    23 KB (2,639 words) - 09:17, 29 July 2024
  • body. The collagen fibers are embedded in a network woven from proteoglycans. A proteoglycan molecule consists of a small core protein with many carbohydrate...
    5 KB (629 words) - 12:23, 11 December 2023
  • Thumbnail for Chondrocyte
    maintain the cartilaginous matrix, which consists mainly of collagen and proteoglycans. Although the word chondroblast is commonly used to describe an immature...
    15 KB (1,815 words) - 21:24, 20 April 2024
  • ligament desmitis, commonly called DSLD, also known as equine systemic proteoglycan accumulation (ESPA), is a systemic disease of the connective tissue of...
    4 KB (464 words) - 15:36, 19 September 2023
  • Thumbnail for Decorin
    Decorin (category Proteoglycans)
    Decorin is a proteoglycan that is on average 90 - 140 kilodaltons (kDa) in molecular weight. It belongs to the small leucine-rich proteoglycan (SLRP) family...
    17 KB (1,949 words) - 09:42, 21 December 2023
  • Thumbnail for Major basic protein
    basic protein, often shortened to major basic protein (MBP; also called Proteoglycan 2 (PRG2)) is encoded in humans by the PRG2 gene. The protein encoded...
    13 KB (1,515 words) - 04:45, 27 January 2024
  • Thumbnail for Adenosine triphosphate
    Antioxidants PRPP Nucleotides Nucleic acids Proteins Glycoproteins & proteoglycans Chlorophylls MEP MVA Acetyl -CoA Polyketides Terpenoid backbones Terpenoids...
    49 KB (5,446 words) - 08:06, 23 August 2024
  • type of cartilage has varying concentrations of components such as proteoglycans, collagen and water which determine its functional properties and location...
    30 KB (3,493 words) - 12:58, 2 June 2024