The 5-HT2A receptor is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and is a G protein-coupled receptor (GPCR). The 5-HT2A...

000-fold higher affinity for the serotonin 5-HT1A receptor over the serotonin 5-HT2A receptor. In relation to this, 5-MeO-DMT has been described as an "atypical"...

5-HT2A receptor 5-HT2B receptor 5-HT2C receptor 5-HT1 receptor 5-HT3 receptor 5-HT4 receptor 5-HT5 receptor 5-HT6 receptor 5-HT7 receptor Category:5-HT2...

serotonin 5-HT2B receptor agonists. 5-HCPC 5-HPEC (weak) 5-HPPC AM1125 AM1476 BF-1 – derived from pimethixene EGIS-7625 – high selectivity over 5-HT2A EXT5...

which activates 5-HT1A, 5-HT1D, 5-HT1B, D2 and norepinephrine receptors. LSD (a psychedelic) is a 5-HT1A, 5-HT2A, 5-HT2C, 5-HT5A and 5-HT6 agonist. The...

non-selective agonists of serotonin receptors. Their hallucinogenic effects are specifically mediated by activation of the 5-HT2A receptor. Drugs that increase extracellular...

vasopressin and oxytocin, mainly via actions of receptor subtypes 5-HT2A and 5-HT2C. Therefore, the 5-HT2C receptor is a significant modulator of the...

incontinence. The 5-HT2C receptors are one of three subtypes that belong to the serotonin 5-HT2 receptor subfamily along with 5-HT2A and 5-HT2B receptors. The development...

blocks 5-HT2A, 5-HT1A, dopamine receptors D1 and D2, histamine receptor H1, and A1 adrenoreceptors. Ketanserin Antihypertensive. Blocks 5-HT2A, 5-HT2C and...

The drug acts as a non-selective serotonin receptor agonist, including of the serotonin 5-HT2A receptor. 5-MeO-MiPT is in a class of compounds commonly...

behavioral proxy of psychedelic effects. The HTR of 5-HTP is blocked by serotonin 5-HT2A receptor antagonists, which block the hallucinogenic effects...

Serotonin receptor and transporter binding studies have yielded conflicting results, including higher and lower serotonin receptor 5-HT2A and serotonin...

the 5-HT2A receptor (EC50 = 3.2 nM, Emax = 78%). It shows 10- to 100-fold selectivity for the 5-HT2A receptor over the 5-HT2B and 5-HT2C receptors and...

lysergamide). They act via serotonin 2A receptor agonism. When compounds bind to serotonin 5-HT2A receptors, they modulate the activity of key circuits...

polymorphism (SNP)—in the human HTR2A gene that codes for the 5-HT2A receptor. 5-HT2A is a neuroreceptor, and several scientific studies have investigated...

psychedelics 2C-D and DOM. The drug is a serotonin receptor agonist, including of the serotonin 5-HT2A receptor. However, it is non-hallucinogenic in animals...

5-HT2A receptor yet discovered, with an affinity (pKi) of 8.88 at the human serotonin 5-HT2A receptor, 100-fold selectivity for the serotonin 5-HT2A receptor...

The 5HT6 receptor is a subtype of 5HT receptor that binds the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5HT). It is a G protein-coupled...

nausea. Psilocin acts as a serotonin 5-HT2A, 5-HT2C, and 5-HT1A receptor agonist or partial agonist. Such receptors are claimed to significantly regulate...

(September 2018). "Modality selective roles of pro-nociceptive spinal 5-HT2A and 5-HT3 receptors in normal and neuropathic states". Neuropharmacology. 143: 29–37...

and acts as a potent agonist for the 5-HT2A and 5-HT2C receptors with a Ki of 0.26 nM at the human 5-HT2A receptor. In drug-substitution experiments in...

arises from biased agonism of the 5-HT2A receptor. Stimulation of the 5-HT2A protomer within the 5-HT2A–mGlu2 receptor complex evokes psychedelic effects...

effect on 5-HT2A/C receptor affinity or intrinsic activity, although 6-fluoro-DET is inactive as a psychedelic despite acting as a 5-HT2A agonist (cf...

highly selective 5-HT2A receptor antagonist that is frequently used in scientific research to investigate the function of the 5-HT2A receptor. It was also...

possibly galactorrhea and amenorrhea. 5-HT2A Receptor: When serotonin is released on to postsynaptic 5-HT2A receptors, the dopamine neuron is inhibited,...

side-to-side head movement that occurs in mice and rats when the serotonin 5-HT2A receptor is activated. Serotonergic psychedelics, including lysergic acid diethylamide...

receptor (or 5-HT1A receptor) is a subtype of serotonin receptors, or 5-HT receptors, that binds serotonin, also known as 5-HT, a neurotransmitter. 5-HT1A...

acts as an antagonist for the 5-HT2A receptor, with a claimed 100x selectivity over the closely related 5-HT2C receptor. While N-benzyl substitution of...

pimavanserin is not a dopamine receptor antagonist, but rather is a selective antagonist or inverse agonist of the serotonin 5-HT2A receptor and to a lesser extent...

hallucinogenic effects via activation of the serotonin 5-HT2A receptor. As a result, serotonin 5-HT2A receptor antagonists would theoretically be expected to...