• Thumbnail for Reverse transcriptase
    A reverse transcriptase (RT) is an enzyme used to convert RNA genome to DNA, a process termed reverse transcription. Reverse transcriptases are used by...
    27 KB (3,047 words) - 16:08, 28 November 2024
  • Reverse-transcriptase inhibitors (RTIs) are a class of antiretroviral drugs used to treat HIV infection or AIDS, and in some cases hepatitis B. RTIs inhibit...
    25 KB (2,897 words) - 23:33, 1 December 2024
  • Thumbnail for Telomerase reverse transcriptase
    Telomerase reverse transcriptase (abbreviated to TERT, or hTERT in humans) is a catalytic subunit of the enzyme telomerase, which, together with the telomerase...
    46 KB (5,304 words) - 20:19, 20 October 2024
  • Thumbnail for Reverse transcription polymerase chain reaction
    template is first converted into a complementary DNA (cDNA) using a reverse transcriptase (RT). The cDNA is then used as a template for exponential amplification...
    44 KB (5,656 words) - 23:37, 29 October 2024
  • Thumbnail for Retrovirus
    cell's cytoplasm, the virus uses its own reverse transcriptase enzyme to produce DNA from its RNA genome, the reverse of the usual pattern, thus retro (backward)...
    41 KB (4,727 words) - 02:05, 8 September 2024
  • include two nucleoside reverse-transcriptase inhibitors (NRTI) as a "backbone" along with one non-nucleoside reverse-transcriptase inhibitor (NNRTI), protease...
    133 KB (15,784 words) - 05:42, 17 September 2024
  • Thumbnail for Geobacillus stearothermophilus
    required to denature DNA. In 2013, a thermostable group II intron reverse transcriptase (TGIRT), GsI-IIC-MRF, from G. stearothermophilus was found to retain...
    8 KB (823 words) - 17:01, 19 October 2024
  • Thumbnail for HIV
    viral RNA genome is converted (reverse transcribed) into double-stranded DNA by a virally encoded enzyme, reverse transcriptase, that is transported along...
    124 KB (14,101 words) - 20:56, 31 December 2024
  • Thumbnail for Lamivudine
    Lamivudine (category Nucleoside analog reverse transcriptase inhibitors)
    food. Lamivudine is a nucleoside reverse transcriptase inhibitor and works by blocking the HIV reverse transcriptase and hepatitis B virus polymerase...
    16 KB (1,566 words) - 08:15, 1 May 2024
  • The WHO Model List of Essential Medicines (aka Essential Medicines List or EML), published by the World Health Organization (WHO), contains the medications...
    67 KB (4,835 words) - 16:55, 29 December 2024
  • Thumbnail for David Baltimore
    material of the cell", specifically the discovery of the enzyme reverse transcriptase. He has contributed to immunology, virology, cancer research, biotechnology...
    80 KB (8,318 words) - 16:02, 24 December 2024
  • Thumbnail for HIV/AIDS
    individual drugs: nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs), non-nucleoside reverse transcriptase, inhibitors (NNRTIs), protease inhibitors...
    211 KB (21,194 words) - 15:30, 2 January 2025
  • Thumbnail for DNA polymerase
    called reverse transcriptase, which is an RNA-dependent DNA polymerase (RdDp) that synthesizes DNA from a template of RNA. The reverse transcriptase family...
    59 KB (7,106 words) - 08:06, 29 December 2024
  • Retron Diversity-generating retroelement Telomerase reverse transcriptase Reverse transcriptase-related cellular gene Ribozyme Spiegelman's Monster Tandem...
    6 KB (719 words) - 03:32, 3 January 2025
  • Thumbnail for Zidovudine
    Zidovudine (category Nucleoside analog reverse transcriptase inhibitors)
    of the nucleoside analog reverse-transcriptase inhibitor (NRTI) class. It works by inhibiting the enzyme reverse transcriptase that HIV uses to make DNA...
    48 KB (4,910 words) - 07:29, 30 November 2024
  • Thumbnail for Transposable element
    transcriptase but lack LTRs, and are transcribed by RNA polymerase II Short interspersed nuclear elements (SINEs) do not encode reverse transcriptase...
    60 KB (7,384 words) - 16:53, 24 December 2024
  • ATC code J05 Antivirals for systemic use is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric...
    6 KB (552 words) - 04:04, 23 December 2024
  • Thumbnail for Bictegravir/emtricitabine/tenofovir alafenamide
    HIV-1 nucleoside analog reverse transcriptase inhibitor; and tenofovir alafenamide, an HIV-1 nucleoside analog reverse transcriptase inhibitor. It was approved...
    14 KB (1,200 words) - 12:24, 8 October 2024
  • Thumbnail for Howard Martin Temin
    1994) was an American geneticist and virologist. He discovered reverse transcriptase in the 1970s at the University of Wisconsin–Madison, for which he...
    17 KB (1,915 words) - 17:41, 14 November 2024
  • Thumbnail for DNA
    that copy the sequence of an RNA strand into DNA. They include reverse transcriptase, which is a viral enzyme involved in the infection of cells by retroviruses...
    166 KB (17,843 words) - 18:18, 22 December 2024
  • double-stranded DNA. This enzyme integrates the DNA produced by reverse transcriptase into the host's genome. A protease is any enzyme that cuts proteins...
    1 KB (135 words) - 06:21, 17 February 2023
  • Thumbnail for Telomerase
    instead uses retrotransposons to maintain telomeres. Telomerase is a reverse transcriptase enzyme that carries its own RNA molecule (e.g., with the sequence...
    49 KB (5,697 words) - 14:29, 22 November 2024
  • Thumbnail for Retron
    sequence found in the genome of many bacteria species that codes for reverse transcriptase and a unique single-stranded DNA/RNA hybrid called multicopy single-stranded...
    7 KB (796 words) - 00:34, 12 May 2023
  • Thumbnail for Riboviria
    acid) from RNA. RNA-dependent DNA polymerase (RdDp), also called reverse transcriptase (RT), produces DNA (deoxyribonucleic acid) from RNA. These enzymes...
    30 KB (3,486 words) - 00:10, 6 December 2024
  • Thumbnail for Eukaryote
    Retron Diversity-generating retroelement Telomerase reverse transcriptase Reverse transcriptase-related cellular gene Ribozyme Spiegelman's Monster Tandem...
    62 KB (6,208 words) - 12:14, 24 December 2024
  • Thumbnail for Ribozyme
    polymerase enzymes. The ribozymes are mutated by reverse transcribing them with reverse transcriptase into various cDNA and amplified with error-prone...
    43 KB (5,174 words) - 14:33, 4 October 2024
  • Thumbnail for Virus
    an RNA intermediate during genome replication. Both types use a reverse transcriptase, or RNA-dependent DNA polymerase enzyme, to carry out the nucleic...
    154 KB (18,258 words) - 21:15, 10 December 2024
  • Thumbnail for Complementary DNA
    genetics, complementary DNA (cDNA) is DNA that was reverse transcribed (via reverse transcriptase) from an RNA (e.g., messenger RNA or microRNA). cDNA...
    19 KB (2,275 words) - 20:43, 3 December 2024
  • Thumbnail for Reverse Transcription Loop-mediated Isothermal Amplification
    by making DNA from the sample RNA. This conversion is made by a reverse transcriptase, an enzyme derived from retroviruses capable of making such a conversion...
    15 KB (1,765 words) - 01:04, 18 June 2024
  • the virion, such as reverse transcriptase and integrase. Lysine tRNA is the primer of the magnesium-dependent reverse transcriptase. The nucleocapsid associates...
    33 KB (3,929 words) - 19:07, 2 September 2024