A sarcomere (Greek σάρξ sarx "flesh", μέρος meros "part") is the smallest functional unit of striated muscle tissue. It is the repeating unit between...
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sarcomere length of cardiac muscle cells, in a resting ventricle, is lower than the optimal length for contraction. There is no bone to fix sarcomere...
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which are in turn composed of myofibrils. Myofibrils are composed of sarcomeres, the basic building blocks of striated muscle tissue. Upon stimulation...
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striated muscle tissues. It connects the Z disc to the M line in the sarcomere. The protein contributes to force transmission at the Z disc and resting...
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Myomesin (section Sarcomere structure)
Myomesin is a protein family found in the M-line of the sarcomere structure. Myomesin has various forms throughout the body in striated muscles with specialized...
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tissue that features repeating functional units called sarcomeres. The presence of sarcomeres manifests as a series of bands visible along the muscle...
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holding onto a knife tightly. ATP is required to reuptake calcium into the sarcomere's sarcoplasmic reticulum (SR). When a muscle is relaxed, the myosin heads...
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proteins, particularly myosin, form structured filaments giving rise to sarcomere (a segment of muscle fibre). Their main aim was to use electron microscopy...
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in 1954. Physiologically, this contraction is not uniform across the sarcomere; the central position of the thick filaments becomes unstable and can...
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are enlarged. It is applied especially to the left ventricle of heart. Sarcomeres are added in series, as for example in dilated cardiomyopathy (in contrast...
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In cardiac physiology, preload is the amount of sarcomere stretch experienced by cardiac muscle cells, called cardiomyocytes, at the end of ventricular...
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the length of the myofibril in sections or units of contraction called sarcomeres. Muscles contract by sliding the thick myosin, and thin actin myofilaments...
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Skeletal muscle cells and cardiac muscle cells both contain myofibrils and sarcomeres and form a striated muscle tissue. Cardiac muscle cells form the cardiac...
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striated – having a striped appearance due to the arrangement of the sarcomeres. A skeletal muscle contains multiple fascicles – bundles of muscle fibers...
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integrates the sarcolemma, Z disk, and nuclear membrane in sarcomeres and regulates sarcomere architecture. Desmin is a 53.5 kD protein composed of 470...
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myosin along the actin filaments causes the shortening and lengthening of the sarcomere; responsible for muscle contraction and relaxation, respectively....
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different components of the sarcomere. In normal muscle cells, the various parts of the muscle fibers that make up the sarcomere are distributed evenly in...
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(59 °F), a phenomenon known as cold shortening occurs, whereby the muscle sarcomeres shrink to a third of their original length. Cold shortening is caused...
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attributed to mutations in one of a number of genes that encode for the sarcomere proteins, and most diagnosed individuals will have an affected parent...
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structural-functional component of striated muscle cells which connects the sarcomere of the muscle to the cell membrane (i.e. the sarcolemma). Costameres are...
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actin movement results in sarcomere shortening. Muscle contraction consists of the simultaneous shortening of multiple sarcomeres. The axon terminal of a...
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that the heart can work like a pump. They occur at the Z line of the sarcomere and can be visualized easily when observing a longitudinal section of...
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cannot contract anymore) Muscle soreness can stem from strain on the sarcomere, the muscle's functional unit, due to the mechanism of activation of the...
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non-genetic (acquired) origin. Genetic cardiomyopathies usually are caused by sarcomere or cytoskeletal diseases, neuromuscular disorders, inborn errors of metabolism...
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DOMS, these ruptures are microscopic lesions at the Z-line of the muscle sarcomere. The soreness has been attributed to the increased tension force and muscle...
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organized into sarcomeres, the fundamental contractile units of muscle cells. The regular organization of myofibrils into sarcomeres gives cardiac muscle...
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bundles of myofibrils, which contain many contractile units known as sarcomeres, which give the tissue its striated (striped) appearance. Skeletal muscle...
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rs071, ISBN 978-0-471-93623-7 Somerville, Laura L.; Wang, Kuan (1988). "Sarcomere matrix of striated muscle: In vivo phosphorylation of titin and nebulin...
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myosin filaments and contain only the actin filaments of neighboring sarcomeres. Bisecting the I band and serving as an anchoring point for the two adjacent...
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biologist specializing in membrane proteins, the cytoskeleton, toxins, and sarcomere structural biochemistry. Since 2014, he has been a director at the Max...
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