• Thumbnail for Amyloid plaques
    Amyloid plaques (also known as neuritic plaques, amyloid beta plaques or senile plaques) are extracellular deposits of the amyloid beta (Aβ) protein mainly...
    32 KB (3,474 words) - 11:13, 10 August 2024
  • Thumbnail for Dementia
    Dementia (redirect from Senile Dementia)
    observed senile plaques, neurofibrillary tangles, and atherosclerotic alteration. At the time, the consensus among medical doctors had been that senile plaques...
    201 KB (22,631 words) - 17:46, 8 August 2024
  • cutaneous condition Pleural plaque, associated with mesothelioma, cancer often caused by exposure to asbestos Senile plaques, an extracellular protein deposit...
    1 KB (206 words) - 01:50, 8 October 2023
  • neurodegenerative condition characterized by two hallmarks: senile plaques and the neurofibrillary tangle. Senile plaques are extracellular aggregations of amyloid-b...
    11 KB (1,669 words) - 00:16, 15 January 2024
  • Thumbnail for Calcification
    Jilong; Du, Peng; Jin, Weilin; Gao, Guo; Cui, Daxiang (2022-11-30). "Senile plaques in Alzheimer's disease arise from Aβ- and Cathepsin D-enriched mixtures...
    9 KB (925 words) - 09:17, 24 July 2024
  • Very low magnification micrograph of cerebral amyloid angiopathy with senile plaques in the cerebral cortex consistent of amyloid beta, as may be seen in...
    26 KB (2,586 words) - 13:58, 6 August 2024
  • Thumbnail for Alzheimer's disease
    brain material is available and can be examined histologically for senile plaques and neurofibrillary tangles. There are three sets of criteria for the...
    184 KB (19,514 words) - 11:02, 10 August 2024
  • (1988). "Multiple transmitter systems contribute neurites to individual senile plaques". Journal of Neuropathology and Experimental Neurology. 47 (2): 138–144...
    18 KB (1,784 words) - 05:30, 11 July 2024
  • tangles, similar to those seen in Alzheimer's disease. Nevertheless, the senile plaques common in Alzheimer's disease are not found. Bhattacharyya, Kalyan B...
    3 KB (230 words) - 18:01, 16 April 2024
  • Thumbnail for Cerebral amyloid angiopathy
    ISBN 9781107014558. Kumar-Singh, S.; Cras, P.; et al. (2002). "Dense-core senile plaques in the Flemish variant of Alzheimer's disease are vasocentric". American...
    18 KB (1,768 words) - 23:46, 18 June 2024
  • Thumbnail for Chronic traumatic encephalopathy
    Loss of neurons, scarring of brain tissue, collection of proteinaceous senile plaques, hydrocephalus, attenuation of the corpus callosum, diffuse axonal injury...
    62 KB (6,591 words) - 19:22, 2 August 2024
  • Thumbnail for Down syndrome
    precursor protein, the gene for which is located on chromosome 21. Senile plaques and neurofibrillary tangles are present in nearly all by 35 years of...
    149 KB (14,922 words) - 13:09, 4 August 2024
  • Thumbnail for Parkinson's disease
    Lewy bodies is common in cortical areas. Neurofibrillary tangles and senile plaques, characteristic of Alzheimer's disease, are uncommon unless the person...
    169 KB (17,796 words) - 21:35, 8 August 2024
  • Thumbnail for Thioflavin
    misfolded protein aggregates called amyloid, both in vitro and in vivo (e.g., plaques composed of amyloid beta found in the brains of Alzheimer's disease patients)...
    11 KB (991 words) - 15:19, 4 April 2024
  • Thumbnail for Aluminium
    (2009). "Demonstration of aluminum in amyloid fibers in the cores of senile plaques in the brains of patients with Alzheimer's disease". Journal of Inorganic...
    135 KB (14,498 words) - 06:56, 9 August 2024
  • Thumbnail for Tauopathy
    insoluble fibrous materials: (1) extracellular amyloid (Aß) protein forming senile plaques and (2) intracellular neurofibrillary lesions (NFL) composed of abnormally...
    19 KB (2,009 words) - 18:07, 29 July 2024
  • Thumbnail for Axonal transport
    amyloid precursor protein (APP), the parent protein that produces the senile plaques found in Alzheimer's disease. A 15-amino acid peptide in the cytoplasmic...
    22 KB (2,622 words) - 22:00, 31 May 2024
  • Thumbnail for Auguste Deter
    Francesco Bonfiglio, they carefully examined her brain to discover senile plaques and neurofibrillary tangles. These would be the hallmark of Alzheimer's...
    13 KB (1,610 words) - 12:38, 26 April 2024
  • formations known as senile plaques. There are different types of plaques, including the diffuse, compact, cored or neuritic plaque types, as well as Aβ...
    65 KB (7,761 words) - 08:45, 1 July 2024
  • Jilong; Du, Peng; Jin, Weilin; Gao, Guo; Cui, Daxiang (April 2023). "Senile plaques in Alzheimer's disease arise from Aβ- and Cathepsin D-enriched mixtures...
    6 KB (526 words) - 04:40, 9 March 2024
  • Thumbnail for Epigenetics of neurodegenerative diseases
    associated neurofibrillary tangles, and by amyloid-beta senile plaques amyloid-beta senile plaques. Several genetic factors have been identified as contributing...
    113 KB (13,392 words) - 02:52, 24 May 2024
  • Thumbnail for Cannabinoid receptor 2
    Alzheimer's disease, beta-amyloid proteins form aggregates known as senile plaques, which disrupt neural functioning. Changes in endocannabinoid levels...
    36 KB (3,880 words) - 22:38, 17 June 2024
  • Thumbnail for Neurofibrillary tangle
    neocortical involvement. This should not be confused with the degree of senile plaque involvement, which progresses differently. Neurofibrillary tangle and...
    25 KB (2,860 words) - 15:17, 20 June 2024
  • Thumbnail for Posterior cortical atrophy
    neurons and synapses, and the presence of neurofibrillary tangles and senile plaques in affected brain regions; this eventually leads to dementia in both...
    19 KB (2,030 words) - 10:40, 21 February 2024
  • Thumbnail for Perivascular space
    Jilong; Du, Peng; Jin, Weilin; Gao, Guo; Cui, Daxiang (2022-11-30). "Senile plaques in Alzheimer's disease arise from Aβ- and Cathepsin D-enriched mixtures...
    33 KB (3,935 words) - 06:47, 8 July 2024
  • Thumbnail for Granule cell
    granule cell dendrites are not an essential component of senile plaques and these plaques have no direct effect on granule cells in the dentate gyrus...
    27 KB (3,175 words) - 15:44, 24 July 2024
  • Thumbnail for Chondroitin sulfate proteoglycan
    markers of Alzheimer's disease are neurofibrillary tangles (NFT) and senile plaques (SP). Studies have shown that CSPGs are present in the frontal cortex...
    15 KB (1,778 words) - 11:24, 12 August 2023
  • Thumbnail for Braak staging
    neocortical involvement. This should not be confused with the degree of senile plaque involvement, which progresses differently. Jubault T, Brambati SM, Degroot...
    9 KB (982 words) - 11:52, 3 December 2023
  • Thumbnail for Teofil Simchowicz
    to work as a consulting neurologist. Simchowicz coined the terms senile plaques, senile index, and granulovacuolar degeneration - discovered in the hippocampus...
    1 KB (158 words) - 12:06, 28 June 2023
  • vacuoles and accumulation of aberrant proteins similar to those found in senile plaques of Alzheimer's disease (amyloid beta, hyperphosphorylated tau, amongst...
    16 KB (1,677 words) - 03:09, 4 August 2024