Thiolated polymers – designated thiomers – are functional polymers used in biotechnology product development with the intention to prolong mucosal drug...
31 KB (3,607 words) - 18:58, 4 August 2024
can be introduced. Another example are thiolated polysaccharides ( see thiomers). Thiol groups are covalently attached to polysaccharides such as hyaluronic...
34 KB (3,912 words) - 06:41, 31 August 2024
three-dimensional tissue formation. Furthermore, thiolated xanthan gum (see thiomers) has shown potential for drug delivery, since by the covalent attachment...
15 KB (1,694 words) - 14:03, 31 August 2024
polymers (=thiomers) can form disulfide bridges with cysteine substructures of keratins getting covalently attached to these proteins. Thiomers exhibit therefore...
39 KB (3,017 words) - 13:44, 1 September 2024
and mucoadhesive properties can be introduced. The thiolated polymer (thiomer) forms disulfide bonds within its polymeric network and with cysteine-rich...
21 KB (2,228 words) - 04:04, 12 August 2024
enhancing properties can be introduced. Thiolated cellulose derivatives (see thiomers) exhibit also high binding properties for metal ions. Cellulose for industrial...
55 KB (5,223 words) - 16:48, 31 August 2024
Thiolated pectin exhibits substantially improved gelling properties since this thiomer is able to crosslink via disulfide bond formation. These high gelling properties...
40 KB (4,719 words) - 14:52, 22 August 2024
molecules into a host. Hyaluronan can be crosslinked by attaching thiols (see thiomers) (trade names: Extracel, HyStem), hexadecylamides (trade name: Hymovis)...
50 KB (5,493 words) - 17:03, 2 September 2024
cells to grow into the dressing. Furthermore, thiolated chitosans (see thiomers) are used for tissue engineering and wound healing, as these biopolymers...
24 KB (3,027 words) - 15:32, 13 July 2024
Sündermann N, Prüfert F, Suchaoin W, et al. (December 2016). "Preactivated thiomers for intranasal delivery of apomorphine: In vitro and in vivo evaluation"...
55 KB (5,980 words) - 23:58, 24 July 2024
polymers) (physical gels) or chemical bonds such as disulfide bonds (see thiomers) (chemical gels), as well as crystallites or other junctions that remain...
37 KB (4,585 words) - 18:10, 8 August 2024
mucoadhesive properties can be introduced as these thiolated oligomers (thiomers) are capable of forming disulfide bonds with cysteine-rich subdomains of...
22 KB (2,498 words) - 01:10, 26 June 2024
contain reversible covalent cross-linking bonds, such as hydrogels of thiomers being cross-linked via disulfide bonds, are non-toxic and are used in numerous...
68 KB (7,768 words) - 06:09, 27 August 2024
crosslink via disulfide bond formation. The use of thiolated polymers (thiomers) as scaffold material for tissue engineering was initially introduced at...
114 KB (13,965 words) - 03:47, 22 August 2024
their ocular residence time can be even improved, as thiolated polymers (thiomers) form disulfide bonds with cysteine-rich subdomains of mucus glycoproteins...
61 KB (6,290 words) - 17:52, 13 August 2024
disulfide bonds are likely most important. Thiolated polymers – designated thiomers – are mucoadhesive polymers that can form disulfide bonds with cysteine-rich...
27 KB (3,243 words) - 16:52, 4 January 2024
Furthermore, thiolation of proteins and carbohydrates enables these polymers (thiomers) to covalently adhere especially to cysteine-rich subdomains of proteins...
19 KB (2,219 words) - 15:07, 12 January 2024
of thiol groups on the surface of nanoparticles or by coating them with thiomers high (muco)adhesive and cellular uptake enhancing properties can be introduced...
125 KB (12,938 words) - 11:36, 16 August 2024
mucoadhesive and in situ gelling polymers and thiolated cyclodextrins (see thiomers). Besides the logistical problems associated with using topicals, there...
27 KB (3,396 words) - 05:49, 26 February 2024
to induce their self-assembly into nanogels. When thiolated polymers (thiomers) are used for this preparation process, nanogels can be further stabilized...
51 KB (5,599 words) - 16:54, 29 September 2023
technologies, such as thiolated polymers, for which he coined the name thiomers in 2000, and phosphatase triggered charge-converting nanoparticles for...
23 KB (2,149 words) - 12:58, 2 June 2024
Studies have also found that the modification of chitosan formulations with thiomers, which can form covalent bonds with mucus, can significantly improve the...
22 KB (2,320 words) - 00:53, 15 August 2023