Troponin, or the troponin complex, is a complex of three regulatory proteins (troponin C, troponin I, and troponin T) that are integral to muscle contraction...

Troponin I is a cardiac and skeletal muscle protein family. It is a part of the troponin protein complex, where it binds to actin in thin myofilaments...

Troponin T (shortened TnT or TropT) is a part of the troponin complex, which are proteins integral to the contraction of skeletal and heart muscles. They...

Troponin C is a protein which is part of the troponin complex. It contains four calcium-binding EF hands, although different isoforms may have fewer than...

release detectable quantities of a marker of injury, typically troponin T or troponin I. Unstable angina is considered to be present in patients with...

Troponin C, also known as TN-C or TnC, is a protein that resides in the troponin complex on actin thin filaments of striated muscle (cardiac, fast-twitch...

is introduced into the cytosol, it binds to the troponin of thin filaments, which causes the troponin-tropomyosin complex to change shape and allow the...

muscle troponin T (cTnT) is a protein that in humans is encoded by the TNNT2 gene. Cardiac TnT is the tropomyosin-binding subunit of the troponin complex...

that is being evaluated to treat amyotrophic lateral sclerosis. It is a troponin activator. "Reldesemtiv - Astellas Pharma/Cytokinetics". AdisInsight. Springer...

the markers currently used are enzymes. For example, in formal usage, troponin would not be listed as a cardiac enzyme. Measuring cardiac biomarkers can...

adenosine diphosphate (ADP) + Pi. Two Ca2+ ions bind to troponin C on the actin filaments. The troponin-Ca2+ complex causes tropomyosin to slide over and unblock...

Troponin I, cardiac muscle is a protein that in humans is encoded by the TNNI3 gene. It is a tissue-specific subtype of troponin I, which in turn is a...

(STEMI), if ST elevation is present. Commonly used blood tests include troponin and less often creatine kinase MB. Treatment of an MI is time-critical...

Troponin C, skeletal muscle is a protein that in humans is encoded by the TNNC2 gene. Troponin (Tn), is a key protein complex in the regulation of striated...

[citation needed] In some locations, the test has been superseded by the troponin test. However, recently, there have been improvements to the test that...

changes and blood test results (a change in cardiac biomarkers such as troponin levels): ST elevation myocardial infarction (STEMI), non-ST elevation myocardial...

acute myocardial infarction, but this test has been largely replaced by troponin. Normal values at rest are usually between 60 and 400 IU/L, where one unit...

Troponin I, fast skeletal muscle is a protein that in humans is encoded by the TNNI2 gene. The TNNI2 gene is located at 11p15.5 in the human chromosomal...

binds to a protein called troponin, which is bound to the actin filament. This binding causes a shape change in the troponin which exposes areas on the...

autoimmune hepatitis. These antibodies can be directed against actin, troponin, and tropomyosin. Dawkins, RL; Joske RA (June 1973). "Immunoglobulin deposition...

(all other types not caused by the heart). Various laboratory tests (CBC, troponin, BNP, etc.) and imaging studies (chest x-ray, CT scan, ultrasound) are...

calcium-binding protein troponin. Contraction is initiated by a calcium-regulated phosphorylation of myosin, rather than a calcium-activated troponin system. Crossbridge...

"Genetically encoded indicators of cellular calcium dynamics based on troponin C and green fluorescent protein". The Journal of Biological Chemistry....

Among many other muscle proteins, present are two regulatory proteins, troponin and tropomyosin. Muscle tissue varies with function and location in the...

surgery, also known as MINS, refers to at least one elevated post-operative troponin level presumed to be of an ischemic mechanism. There is an absence of any...

it. When a nerve impulse arrives, Ca2+ ions cause troponin to change shape; this moves the troponin + tropomyosin complex away, leaving the myosin binding...

continuous telemetry monitoring. Troponin levels should also be ordered. Important to note, negative findings on both ECG and troponin levels do not exclude BCI...

two proteins, tropomyosin and troponin. Tropomyosin inhibits the interaction between actin and myosin, while troponin senses the increase in calcium...

contractions are caused by calcium's bonding to troponin and unmasking the binding sites covered by the troponin-tropomyosin complex on the actin myofilament...

harmful potential compared to others (β-myosin heavy chain). For example, troponin T mutations were originally associated with a 50% mortality before the...