Urokinase, also known as urokinase-type plasminogen activator (uPA), is a serine protease present in humans and other animals. The human urokinase protein...
20 KB (2,290 words) - 08:13, 18 December 2024
The Urokinase receptor, also known as urokinase plasminogen activator surface receptor (uPAR) or CD87 (Cluster of Differentiation 87), is a protein encoded...
10 KB (1,151 words) - 09:59, 3 December 2023
the principal inhibitor of tissue-type plasminogen activator (tPA) and urokinase (uPA), the activators of plasminogen and hence fibrinolysis (the physiological...
13 KB (1,603 words) - 02:15, 10 March 2024
Soluble urokinase plasminogen activator receptor (suPAR) (NCBI Accession no. AAK31795) is a protein and the soluble form of uPAR. uPAR is expressed mainly...
13 KB (1,767 words) - 18:16, 12 March 2024
[citation needed] Some fibrinolytics are: Streptokinase (Kabikinase) Urokinase Recombinant tissue plasminogen activators (rtPA) Alteplase (Activase or...
18 KB (2,060 words) - 15:10, 6 November 2024
with weak potency (IC50 = 87 mM), and it can block the active-site of urokinase plasminogen activator (uPA) with high specificity (Ki = 2 mM), one of...
44 KB (4,066 words) - 00:03, 11 December 2024
failure, as determined by blood levels of a protein called suPAR (soluble urokinase plasminogen activator receptor) of at least 6 ng per ml." In November...
24 KB (2,084 words) - 05:31, 21 October 2024
into the clot when it is formed. Tissue plasminogen activator (t-PA) and urokinase are the agents that convert plasminogen to the active plasmin, thus allowing...
9 KB (1,074 words) - 23:37, 19 December 2024
formed during blood clotting. There are two main plasminogen activators: urokinase (uPA) and tissue plasminogen activator (tPA). Tissue plasminogen activators...
9 KB (1,080 words) - 11:10, 2 September 2024
Thrombophilia Urokinase Activates plasminogen Quebec platelet disorder Plasminogen activator inhibitor-1 PAI-1 Inactivates tPA and urokinase (endothelial...
64 KB (6,553 words) - 00:22, 16 December 2024
pathogenesis of kidney diseases. Reiser discovered the role of suPAR (soluble urokinase plasminogen activator receptor) as a global, circulating risk factor for...
17 KB (1,652 words) - 00:03, 21 December 2024
Organization (WHO): One study has proposed that elevated levels of soluble urokinase-type plasminogen activator receptor (SuPAR) in seminal plasma might be...
8 KB (646 words) - 03:24, 16 December 2023
complications may include catheter occlusion, phlebitis and bleeding. Urokinase or low-dose tissue plasminogen activator (tPA) may be required to break...
14 KB (1,570 words) - 05:04, 16 December 2024
Pharmaceutical Lymphatic cancer therapeutic Ficin Pharmaceutical Digestive aid Urokinase Pharmaceutical Anticoagulant β-Lactamase Pharmaceutical Penicillin allergy...
15 KB (1,580 words) - 20:41, 27 August 2024
plasminogen activator. Urokinase plasminogen activator receptor (uPAR) is a cofactor for plasminogen activation by urokinase plasminogen activator. The...
15 KB (1,821 words) - 23:09, 9 November 2024
Urispas Uristat Urobak Urocit-K Urodine urofollitropin (INN) urokinase alfa (INN) urokinase (INN) Urologic Uromitexan Uroplus Ds Uroplus Ss Uroplus Urorec...
5 KB (348 words) - 03:40, 18 December 2024
Ly6 also known as lymphocyte antigen 6 or urokinase-type plasminogen activator receptor (uPAR) is family of proteins that share a common structure but...
7 KB (724 words) - 06:05, 29 November 2023
coagulation factor that inactivates tissue plasminogen activator and urokinase. It is present in most cells, especially monocytes/macrophages. PAI-2...
23 KB (2,909 words) - 16:49, 26 July 2024
g., recombinant tissue plasminogen activator (tPA), streptokinase, or urokinase). A percutaneous catheter inserted into the femoral artery and threaded...
23 KB (2,333 words) - 09:54, 14 October 2024
variable inhibition of the blood peptidases Factor Xa, thrombin, and urokinase-type plasminogen activator. MEROPS entry for ecotin MEROPS peptidase family...
2 KB (217 words) - 13:43, 21 June 2022
TRIPOTASSIUM DICITRATE BISMUTHATE 518. TROMANTADINE HYDROCHLORIDE 519. UROKINASE 520. VALSARTAN 521. VASOPRESSIN 522. VECURONIUM BROMIDE 523. VENLAFAXINE...
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needed] and SCD1, for predicting response to therapeutic regimens, and urokinase plasminogen activator, PA1-1 and SCD1 for assessing prognosis.[medical...
140 KB (15,850 words) - 19:18, 21 December 2024
range of pathogens, including HIV-1. Urine can also be used to produce urokinase, which is used clinically as a thrombolytic agent.[citation needed] Applying...
45 KB (5,473 words) - 16:59, 3 December 2024
dual therapy combination of mutant prourokinase (the precursor form of urokinase) and a small dose of tPA [Tissue Plasminogen Activator]. TSI is developing...
2 KB (159 words) - 18:55, 2 January 2021
better patient outcomes. A 2012 systematic review found that soluble urokinase-type plasminogen activator receptor (SuPAR) is a nonspecific marker of...
124 KB (13,425 words) - 05:59, 3 December 2024
mechanical stress causes epithelial cells to express an increased activity of urokinase plasminogen activator (uPA). Increased uPA activity initiates conversion...
22 KB (2,475 words) - 05:46, 24 September 2024
that cannot be dissolved by other compounds, such as streptokinase and urokinase.[citation needed] The processes of blood anticoagulation by hementin includes...
3 KB (373 words) - 20:26, 31 December 2023
blood clots. This is achieved by the administration of a drug (such as urokinase or alteplase) that activates plasmin, an enzyme that occurs naturally...
37 KB (4,360 words) - 17:27, 18 October 2024
retention. Blood clots that remain in the bladder are digested by urinary urokinase producing fibrin fragments. These fibrin fragments are natural anticoagulants...
29 KB (3,162 words) - 09:17, 19 October 2024
Shen, Y Guo, C Du, M Wilczynska, S Hellström, T Ny, Mice Deficient in Urokinase-Type Plasminogen Activator Have Delayed Healing of Tympanic Membrane Perforations...
25 KB (2,756 words) - 01:50, 19 November 2024