• Thumbnail for Clopidogrel
    Clopidogrel, sold under the brand name Plavix among others, is an antiplatelet medication used to reduce the risk of heart disease and stroke in those...
    44 KB (3,710 words) - 04:08, 21 November 2024
  • Thumbnail for Ticagrelor
    whether clopidogrel is significantly influenced by such variants). Ticagrelor was found to result in a lower risk of stroke at 90 days than clopidogrel, which...
    33 KB (3,133 words) - 06:31, 11 November 2024
  • Thumbnail for Prasugrel
    PCI. Prasugrel is associated with a higher bleeding risk compared to clopidogrel but has demonstrated superiority in reducing the composite endpoint of...
    21 KB (2,024 words) - 11:42, 21 October 2024
  • Thumbnail for Omeprazole
    clopidogrel to prevent these events. This interaction is possible because omeprazole is an inhibitor of the enzymes CYP2C19 and CYP3A4. Clopidogrel is...
    42 KB (3,798 words) - 13:39, 31 December 2024
  • ticlopidine but due to adverse effects it is not much used today. Ticlopidine, clopidogrel and prasugrel (Efient) are all thienopyridines that cause irreversible...
    46 KB (5,282 words) - 08:16, 30 March 2024
  • Thumbnail for CYP2C19
    drugs in current clinical use, most notably the antiplatelet treatment clopidogrel (Plavix), drugs that treat pain associated with ulcers, such as omeprazole...
    39 KB (3,879 words) - 02:14, 11 August 2024
  • extended-release dipyridamole, or clopidogrel alone. Clopidogrel and aspirin have similar efficacies and side effect profiles. Clopidogrel is more expensive and has...
    45 KB (5,126 words) - 12:30, 17 November 2024
  • Thumbnail for Esomeprazole
    increase if they are used concomitantly with esomeprazole. Conversely, clopidogrel (Plavix) is an inactive prodrug that partially depends on CYP2C19 for...
    31 KB (2,777 words) - 08:32, 19 October 2024
  • therapy. Often a combination of aspirin plus an ADP/P2Y inhibitor (such as clopidogrel, prasugrel, ticagrelor, or another) is used to obtain greater effectiveness...
    18 KB (1,752 words) - 10:58, 11 August 2024
  • Thumbnail for Angioplasty
    antiplatelet therapy (DAPT) which consists of a P2Y12 inhibitor, such as clopidogrel, which is taken at the same time as acetylsalicylic acid (aspirin). Dual...
    38 KB (4,158 words) - 20:05, 25 August 2024
  • Thumbnail for Fenethylline
    AR-C 67085MX AR-C 69931MX AR-C 118925XX ATP BzATP C1330-7 Cangrelor Clopidogrel Elinogrel Ip5I MRS-2179 MRS-2211 MRS-2279 MRS-2395 MRS-2500 MRS-2578...
    53 KB (5,272 words) - 01:49, 29 December 2024
  • Thumbnail for Ticlopidine
    desirable. With the advent of newer and safer antiplatelet drugs such as clopidogrel and ticagrelor, its use remained limited. It was patented in 1973 and...
    18 KB (1,724 words) - 08:54, 9 September 2024
  • Thumbnail for Myocardial infarction
    continued indefinitely, as well as another antiplatelet agent such as clopidogrel or ticagrelor ("dual antiplatelet therapy" or DAPT) for up to twelve...
    129 KB (13,819 words) - 18:06, 31 December 2024
  • Thumbnail for Aspirin
    Frequently, aspirin is combined with an ADP receptor inhibitor, such as clopidogrel, prasugrel, or ticagrelor to prevent blood clots. This is called dual...
    155 KB (16,757 words) - 17:49, 11 December 2024
  • Thumbnail for Stroke
    expensive. Both aspirin and clopidogrel may be useful in the first few weeks after a minor stroke or high-risk TIA. Clopidogrel has less side effects than...
    187 KB (20,646 words) - 11:42, 22 December 2024
  • Thumbnail for Repaglinide
    repaglinide and may lead to hypoglycemia. Co-administration of repaglinide and clopidogrel (a CYP2C8 inhibitor) may lead to a significant decrease in blood glucose...
    10 KB (990 words) - 13:31, 19 December 2023
  • Thumbnail for Pantoprazole
    medications that are affected include bisphosphonate derivatives, fluconazole, clopidogrel, and methotrexate. The mechanism of action of pantoprazole is to inhibit...
    35 KB (2,696 words) - 22:19, 1 November 2024
  • Thumbnail for Nucleotide
    AR-C 67085MX AR-C 69931MX AR-C 118925XX ATP BzATP C1330-7 Cangrelor Clopidogrel Elinogrel Ip5I MRS-2179 MRS-2211 MRS-2279 MRS-2395 MRS-2500 MRS-2578...
    32 KB (3,305 words) - 19:08, 12 December 2024
  • Thumbnail for Dipyridamole
    patients presenting after cerebral ischemia. A triple therapy of aspirin, clopidogrel, and dipyridamole has been investigated, but this combination led to...
    11 KB (891 words) - 17:40, 20 November 2024
  • Thumbnail for Glucose-6-phosphate dehydrogenase deficiency
    that G6PD deficiency could reduce the antiplatelet efficacy of clopidogrel (clopidogrel resistance). G6PD deficiency is the second most common human enzyme...
    38 KB (3,970 words) - 13:30, 31 October 2024
  • Thumbnail for Milvexian
    BMS-986177 for the Prevention of a Stroke in Patients Receiving Aspirin and Clopidogrel (AXIOMATIC-SSP)". ClinicalTrial.gov. U.S. National Library of Medicine...
    4 KB (173 words) - 05:43, 28 June 2023
  • Thumbnail for Cytidine monophosphate
    AR-C 67085MX AR-C 69931MX AR-C 118925XX ATP BzATP C1330-7 Cangrelor Clopidogrel Elinogrel Ip5I MRS-2179 MRS-2211 MRS-2279 MRS-2395 MRS-2500 MRS-2578...
    3 KB (144 words) - 17:01, 30 April 2023
  • Thumbnail for Ketorolac
    time. The risk of bleeding increases with the concurrent medications clopidogrel, cefoperazone, valproic acid, cefotetan, eptifibatide, tirofiban, and...
    31 KB (2,639 words) - 23:45, 9 December 2024
  • Thumbnail for Proton-pump inhibitor
    interaction between PPIs and the metabolism of the platelet inhibitor clopidogrel is known and this drug is also often used in people with cardiac disease...
    59 KB (6,368 words) - 17:04, 23 December 2024
  • Thumbnail for Coronary artery disease
    risk may still find the potential benefits worth the associated risks. Clopidogrel plus aspirin (dual anti-platelet therapy) reduces cardiovascular events...
    107 KB (10,943 words) - 21:17, 1 January 2025
  • Thumbnail for Cangrelor
    adenosine diphosphate-mediated platelet activation and aggregation. Unlike clopidogrel (Plavix), which is a prodrug, cangrelor is an active drug not requiring...
    15 KB (1,150 words) - 05:23, 3 March 2024
  • Thumbnail for CADASIL
    patients are limited. Antiplatelet agents such as aspirin, dipyridamole, or clopidogrel might help prevent strokes; however, anticoagulation may be inadvisable...
    19 KB (1,899 words) - 06:05, 20 June 2024
  • Thumbnail for Anticoagulant
    older anticoagulants (e.g., warfarin) and antiplatelet agents (e.g., clopidogrel, ticlopidine, prasugrel, ticagrelor, and/or aspirin) should not be altered...
    78 KB (8,755 words) - 07:51, 27 October 2024
  • Thumbnail for Medicinal chemistry
    classes of small organic molecules (e.g., atorvastatin, fluticasone, clopidogrel) and "biologics" (infliximab, erythropoietin, insulin glargine), the...
    16 KB (1,937 words) - 11:15, 19 October 2024
  • Thumbnail for CYP3A4
    (beta agonist) warfarin, (anticoagulant) clopidogrel becoming bioactivated (antiplatelet), 2-oxo-clopidogrel, omeprazole, (proton pump inhibitor) nateglinide...
    80 KB (7,794 words) - 00:31, 3 December 2024