Prostaglandin E2 (PGE2), also known as dinoprostone, is a naturally occurring prostaglandin with oxytocic properties that is used as a medication. Dinoprostone...
34 KB (3,565 words) - 20:10, 14 May 2024
growth. Prostaglandin E2 (PGE2) — the most abundant prostaglandin — is generated from the action of prostaglandin E synthases on prostaglandin H2 (prostaglandin...
24 KB (2,463 words) - 17:42, 11 July 2024
The prostaglandin E2 (PGE2) receptors are G protein-coupled receptors that bind and are activated by prostaglandin E2. They are members of the prostaglandin...
5 KB (509 words) - 01:31, 17 December 2023
Prostaglandin E2 receptor 2, also known as EP2, is a prostaglandin receptor for prostaglandin E2 (PGE2) encoded by the human gene PTGER2: it is one of...
32 KB (3,685 words) - 02:56, 10 March 2024
Prostaglandin EP3 receptor (EP3, 53kDa), is a prostaglandin receptor for prostaglandin E2 (PGE2) encoded by the human gene PTGER3; it is one of four identified...
38 KB (4,320 words) - 05:35, 12 August 2024
Prostaglandin E2 receptor 1 (EP1) is a 42kDa prostaglandin receptor encoded by the PTGER1 gene. EP1 is one of four identified EP receptors, EP1, EP2, EP3...
20 KB (2,320 words) - 00:41, 17 July 2024
sequence, for the insulin gene Levuglandin E2, an aldehyde Prostaglandin E2, an abortifacient Prostaglandin E2 receptor, a human gene Iodine-deficiency...
4 KB (571 words) - 00:32, 29 July 2024
"Structural basis for induced formation of the inflammatory mediator prostaglandin E2". Proceedings of the National Academy of Sciences. 105 (32): 11110–11115...
3 KB (205 words) - 15:33, 26 August 2023
Prostaglandin E2 receptor 4 (EP4) is a prostaglandin receptor for prostaglandin E2 (PGE2) encoded by the PTGER4 gene in humans; it is one of four identified...
40 KB (4,808 words) - 02:56, 28 March 2024
Cyclooxygenase (redirect from Prostaglandin-endoperoxide synthase)
Cyclooxygenase (COX), officially known as prostaglandin-endoperoxide synthase (PTGS), is an enzyme (specifically, a family of isozymes, EC 1.14.99.1)...
16 KB (1,779 words) - 11:08, 3 July 2024
Aspirin (section Prostaglandins and thromboxanes)
of Surgeons in London, showed aspirin suppressed the production of prostaglandins and thromboxanes. For this discovery he was awarded the 1982 Nobel Prize...
152 KB (16,395 words) - 02:17, 2 September 2024
alprostadil Prostaglandin E2 also known as dinoprostone Both types are on the World Health Organization's List of Essential Medicines. Prostaglandin E play...
5 KB (148 words) - 21:50, 4 March 2021
Prostaglandin E1 (PGE1) is a naturally occurring prostaglandin and is also used as a medication (alprostadil). In infants with congenital heart defects...
13 KB (1,105 words) - 07:16, 28 May 2024
Prostaglandin F2α (PGF2α in prostanoid nomenclature), pharmaceutically termed dinoprost is a naturally occurring prostaglandin used in medicine to induce...
12 KB (1,134 words) - 18:55, 24 April 2024
administered intravenously to horses. A single dose has been shown to reduce prostaglandin E2 production and inflammatory exudate for up to 15 hours, although there...
18 KB (1,686 words) - 00:29, 13 August 2024
the prostaglandin EP4 receptor, one out of the four prostaglandin E2 (PGE2) receptor subgroups. The EP4 receptor then mediates the prostaglandin-E2-elicited...
11 KB (1,033 words) - 23:56, 28 March 2024
Cyclooxygenase-1 (redirect from Prostaglandin-endoperoxide synthase 1)
Cyclooxygenase 1 (COX-1), also known as prostaglandin-endoperoxide synthase 1 (HUGO PTGS1), is an enzyme that in humans is encoded by the PTGS1 gene....
18 KB (2,122 words) - 12:15, 2 June 2024
of prostaglandin synthase. NSAIDs have antipyretic activity and can be used to treat fever. Fever is caused by elevated levels of prostaglandin E2 (PGE2)...
110 KB (11,559 words) - 22:46, 13 August 2024
12-Hydroxyheptadecatrienoic acid) Prostaglandin D2 synthase to create prostaglandin D2 Prostaglandin E synthase to create prostaglandin E2 It rearranges non-enzymatically...
6 KB (505 words) - 01:38, 1 March 2024
Cyclooxygenase-2 (redirect from Prostaglandin-endoperoxide synthase 2)
Cyclooxygenase-2 (COX-2), also known as Prostaglandin-endoperoxide synthase 2 (HUGO PTGS2), is an enzyme that in humans is encoded by the PTGS2 gene....
30 KB (3,417 words) - 14:36, 15 May 2024
non-selectively to block the prostaglandin synthesis by inhibition of prostaglandin G/H synthesis 1 and 2. Prostaglandin functions in the body as a messenger...
25 KB (2,264 words) - 19:45, 31 August 2024
Prostacyclin (redirect from Prostaglandin I2)
Prostacyclin (also called prostaglandin I2 or PGI2) is a prostaglandin member of the eicosanoid family of lipid molecules. It inhibits platelet activation...
20 KB (1,639 words) - 08:58, 22 December 2023
especially similar to selective COX-2 inhibitors. Paracetamol inhibits prostaglandin synthesis by reducing the active form of COX-1 and COX-2 enzymes. This...
123 KB (12,189 words) - 17:43, 1 September 2024
Misoprostol (category Prostaglandins)
Misoprostol is a synthetic prostaglandin medication used to prevent and treat stomach and duodenal ulcers, induce labor, cause an abortion, and treat...
51 KB (4,767 words) - 15:29, 17 July 2024
action by reducing the production of inflammatory mediators called prostaglandins. It is metabolized by the liver to inactive metabolites. Naproxen was...
34 KB (3,174 words) - 04:50, 18 July 2024
antipyretic effects. It acts by inhibiting the body's production of prostaglandin. It was patented in 1967 and approved for medical use in 1980. Ketoprofen...
18 KB (1,848 words) - 13:53, 1 July 2024
Sulprostone is an analogue of prostaglandin E2 (PGE2) that has oxytocic activity in assays of rat kidney cells and tissues. There are four known receptors...
6 KB (433 words) - 05:50, 6 May 2024
swelling from inflammation. It works by inhibiting the production of prostaglandins, endogenous signaling molecules known to cause these symptoms. It does...
23 KB (2,294 words) - 14:58, 28 July 2024
growths in the intestinal tract. Overexpression of COX-2 produces excess prostaglandins, which have been shown to increase the possibility of colorectal cancer...
42 KB (4,944 words) - 11:56, 4 April 2024
Prostaglandin analogues are a class of drugs that bind to a prostaglandin receptor. Wider use of prostaglandin analogues is limited by unwanted side effects...
3 KB (342 words) - 21:37, 11 July 2024