(GLUT4), also known as solute carrier family 2, facilitated glucose transporter member 4, is a protein encoded, in humans, by the SLC2A4 gene. GLUT4 is...

The drug metformin phosphorylates GLUT4, thereby increasing its sensitivity to insulin. During fasting, some GLUT4 transporters will be expressed at the...

enhances peripheral glucose uptake (by inducing the phosphorylation of GLUT4 enhancer factor), decreases insulin-induced suppression of fatty acid oxidation...

be important in the insulin pathway with its involvement with GLUT4 trafficking. GLUT4 plays a crucial role in maintaining glucose balance, and is primarily...

this by decreasing the translocation of glucose transporters (especially GLUT4) to the cell membrane. Based on the significant improvement in insulin sensitivity...

transporter GLUT4 to the plasma membrane, and this translocation process is dependent on phosphorylation of AS160. The role of AS160 in GLUT4 translocation...

highly expressed in nerve cells. Glucose from the bloodstream is taken up by GLUT4 from muscle cells (of the skeletal muscle and heart muscle) and fat cells...

increase in enzymes which specialize in glucose uptake in cells such as GLUT4 and hexokinase II are thought to be mediated in part by AMPK when it is...

It suppresses lipid accumulation through repression of C/EBPα-activated GLUT4-mediated glucose uptake in 3T3-L1 cells. LC Method for Analysis of Three...

fats. The fat cells take up glucose through special glucose transporters (GLUT4), whose numbers in the cell wall are increased as a direct effect of insulin...

regulates a glucose transporter called GLUT4. TUG-UBL1 is an acronym for Tether containing UBX domain for GLUT4-Ubiquitin Like 1, this is encoded for by...

through the GLUT4 transporter, thus decreasing blood sugar. When insulin binds to the receptors on the cell surface, vesicles containing the GLUT4 transporters...

resistance) by decreasing the translocation of glucose transporters (especially GLUT4) to the cell membrane. Cortisol also increases glycogen synthesis (glycogenesis)...

thought that exercise causes the glucose receptor GLUT4 to translocate to the membrane. As more GLUT4 receptors are present on the membrane more glucose...

subclasses. Class I comprises the well-characterized glucose transporters GLUT1-GLUT4. Class II comprises: GLUT5 (SLC2A5), a fructose transporter in enterocytes...

Activated PKB facilitates the fusion of GLUT4 containing endosomes with the cell membrane, resulting in an increase in GLUT4 transporters in the plasma membrane...

regulatory element and novel DNA binding protein that regulates the human GLUT4 promoter in transgenic mice". J Biol Chem. 275 (31): 23666–73. doi:10.1074/jbc...

insulin and exercise cause translocation of GLUT4 to the plasma membrane. Except for the fundamental process of GLUT4 translocation, [muscle glucose uptake...

transporter GLUT4. He has also been responsible for the molecular dissection of the intracellular trafficking pathways that regulate GLUT4 translocation...

across plasma membranes. The Hexose Transporter proteins GLUT1, GLUT3 and GLUT4 transfer only the oxydized dehydroascorbic acid (DHA) form of vitamin C...

against insulin resistance induced by hydrogen peroxide with restoration of GLUT4 translocation". Metabolism. 55 (6): 722–730. doi:10.1016/j.metabol.2006...

information can be found by searching their databases (for an example of the GLUT4 transporter pictured here, see citation). These profiles indicate the level...

principal transporter for transfer of glucose between liver and blood Unlike GLUT4, it does not rely on insulin for facilitated diffusion. In humans, this...

role in the linkage of the glucose transporter (GLUT4) to the insulin signaling pathway. The activated GLUT4 will translocate to the cell membrane and promotes...

increased insulin receptor sensitivity while Akt and PI3-K led to enhanced GLUT4 translocation to the cell surface, thus causing greater uptake of glucose...

via insulin-sensitive pathways (insulin regulated transporters GLUT1 and GLUT4). Instead, fructose is taken in by GLUT5. Fructose in muscles and adipose...

Dehvari N, Olsen JM, Kocan M, et al. (May 2019). "BRL37344 stimulates GLUT4 translocation and glucose uptake in skeletal muscle via β2-adrenoceptors...

greater transport capacity than GLUT1 or GLUT4, as well as a higher glucose affinity than GLUT1, GLUT2 or GLUT4. This is significant as glucose levels surrounding...

(December 2010). "Pachymic acid stimulates glucose uptake through enhanced GLUT4 expression and translocation". European Journal of Pharmacology. 648 (1–3):...

insulin concentrations, muscle increases GLUT4 translocation of and glucose uptake. The mechanism for increased GLUT4 translocation is an area of ongoing research...