• Thumbnail for P53
    p53, also known as Tumor protein P53, cellular tumor antigen p53 (UniProt name), or transformation-related protein 53 (TRP53) is a regulatory protein that...
    123 KB (13,103 words) - 09:17, 25 July 2024
  • p53 is a tumor suppressor protein. P53 may also refer to: p53 (band), an experimental music group p53 (album), their 1996 live album Curtiss XP-53, an...
    616 bytes (115 words) - 22:50, 23 October 2022
  • Thumbnail for Pattern 1853 Enfield
    Enfield Pattern 1853 rifle-musket (also known as the Pattern 1853 Enfield, P53 Enfield, and Enfield rifle-musket) was a .577 calibre Minié-type muzzle-loading...
    17 KB (2,303 words) - 10:46, 27 May 2024
  • Thumbnail for Mdm2
    p53 tumor suppressor. Mdm2 protein functions both as an E3 ubiquitin ligase that recognizes the N-terminal trans-activation domain (TAD) of the p53 tumor...
    34 KB (3,955 words) - 22:16, 10 June 2024
  • Thumbnail for INS Savitri (P53)
    INS Savitri (P53) is a Sukanya class patrol vessel of the Indian Navy. Wikimedia Commons has media related to INS Savitri (P53). "Surface Ships of Indian...
    2 KB (45 words) - 08:03, 23 August 2022
  • p53 is a 1996 live album by experimental music group p53. It was their debut album and was recorded at the 25th Frankfurt Jazz Festival in Germany on 16...
    6 KB (522 words) - 05:01, 20 January 2021
  • p53 was an experimental music group commissioned by English percussionist Chris Cutler to play at the 25th Frankfurt Jazz Festival in Germany in September...
    8 KB (754 words) - 12:55, 6 April 2024
  • Thumbnail for Oncovirus
    tumor proteins p53 and the retinoblastoma proteins (Rb). It is evolutionarily advantageous for viruses to inactivate p53 because p53 can trigger cell...
    52 KB (6,056 words) - 11:36, 25 July 2024
  • Thumbnail for P53 upregulated modulator of apoptosis
    The p53 upregulated modulator of apoptosis (PUMA) also known as Bcl-2-binding component 3 (BBC3), is a pro-apoptotic protein, member of the Bcl-2 protein...
    28 KB (3,387 words) - 06:12, 27 December 2023
  • gene. It consists of recombinant adenovirus engineered to code for p53 protein (rAd-p53) and is manufactured by Shenzhen SiBiono GeneTech. Gendicine was...
    7 KB (429 words) - 09:52, 3 June 2024
  • The p53 p63 p73 family is a family of tumor suppressor genes. This gene family codes the proteins: p53 TP73L (also known as "p63") p73 They are sometimes...
    4 KB (469 words) - 10:59, 23 December 2023
  • Thumbnail for TP53BP1
    Tumor suppressor p53-binding protein 1 also known as p53-binding protein 1 or 53BP1 is a protein that in humans is encoded by the TP53BP1 gene. 53BP1...
    14 KB (1,731 words) - 19:32, 22 December 2023
  • Thumbnail for Cell division
    cyclin-CDK complexes. The p53 tumor-suppressor protein plays a crucial role at the G1/S checkpoint and the G2/M checkpoint. Activated p53 proteins result in...
    38 KB (4,283 words) - 14:51, 25 July 2024
  • Thumbnail for P21
    primarily associated with inhibition of CDK2. p21 represents a major target of p53 activity and thus is associated with linking DNA damage to cell cycle arrest...
    34 KB (3,978 words) - 08:00, 23 February 2024
  • suppressor, p53. p53 is an apoptosis transcription factor normally found in the cytosol. When cellular DNA is damaged beyond repair, p53 is transported...
    42 KB (4,944 words) - 11:56, 4 April 2024
  • Thumbnail for TP63
    significantly later than p53, phylogenetic analysis of p53, p63 and p73, suggest that p63 was the original member of the family from which p53 and p73 evolved...
    21 KB (2,378 words) - 06:27, 13 July 2024
  • Thumbnail for ThinkPad P series
    processors and Nvidia Quadro Pascal-based graphics. A redesign of the P52, the P53 features a 4K UHD OLED Touch display, Wi-Fi 6, Intel 9th Gen Coffee Lake...
    76 KB (1,980 words) - 20:50, 19 July 2024
  • P53 regulation associated lncRNA is a protein that in humans is encoded by the PRAL gene. "Human PubMed Reference:". National Center for Biotechnology...
    440 bytes (43 words) - 22:57, 22 February 2024
  • Thumbnail for Transversion
    respectively. The mutation of the P53 gene is the most common gene mutation found in cancer cells. A study has shown that p53 mutations are common in tobacco-related...
    6 KB (740 words) - 09:42, 24 March 2024
  • Thumbnail for Tumor suppressor gene
    as certain mutations in the p53 gene product. p53 mutations can function as a dominant negative, meaning that a mutated p53 protein can prevent the function...
    30 KB (3,409 words) - 03:56, 11 June 2024
  • and post-translational modification of proteins, for example, histones, p53, and tubulins. Among these proteins, chromatin proteins and metabolic enzymes...
    42 KB (4,895 words) - 08:33, 15 January 2024
  • P53-responsive gene 1 is a protein that in humans is encoded by the PRG1 gene. "Human PubMed Reference:". National Center for Biotechnology Information...
    2 KB (238 words) - 15:56, 12 August 2023
  • Thumbnail for Heterogeneous ribonucleoprotein particle
    coordination with p53. hnRNP K is rapidly induced after DNA damage by ionizing radiation. It cooperates with p53 to induce the activation of p53 target genes...
    17 KB (2,028 words) - 04:21, 17 June 2024
  • P53 road is a regional road (P-Highway) in Zakarpattia Oblast, Ukraine. It runs north-south and connects Malyi Bereznyi with a Slovakia-Ukraine border...
    2 KB (85 words) - 18:57, 15 July 2022
  • Thumbnail for USP7
    tumor suppressor protein, p53. Normally, p53 levels are kept low in part due to Mdm2-mediated ubiquitylation and degradation of p53. In response to oncogenic...
    19 KB (2,287 words) - 17:30, 19 July 2024
  • Thumbnail for Li–Fraumeni syndrome
    in the TP53 tumor suppressor gene, which encodes a transcription factor (p53) that normally regulates the cell cycle and prevents genomic mutations. The...
    18 KB (2,068 words) - 14:38, 20 July 2024
  • Thumbnail for Survivin
    not well understood, but regulation of survivin seems to be linked to the p53 protein. It also is a direct target gene of the Wnt pathway and is upregulated...
    62 KB (8,387 words) - 23:21, 6 November 2023
  • Thumbnail for Nutlin
    analogs which inhibit the interaction between mdm2 and tumor suppressor p53, and which were discovered by screening a chemical library by Vassilev et...
    7 KB (657 words) - 15:17, 20 May 2024
  • Thumbnail for Norton Commander (motorcycle)
    second was the dual-seat P53 civilian tourer. Both the P52 and P53 had panniers integral with their fibreglass bodywork. The P53 bodywork was later revised...
    3 KB (185 words) - 04:03, 19 March 2023
  • Thumbnail for Glioblastoma
    most have higher than normal expression of EGFR, whereas the gene TP53 (p53), which is often mutated in glioblastoma, is rarely mutated in this subtype...
    80 KB (8,694 words) - 09:04, 27 July 2024