Scrapie (/ˈskreɪpi/) is a fatal, degenerative disease affecting the nervous systems of sheep and goats. It is one of several transmissible spongiform...
43 KB (5,035 words) - 18:55, 18 October 2024
uncertain function. They are the hypothesized cause of various TSEs, including scrapie in sheep, chronic wasting disease (CWD) in deer, bovine spongiform encephalopathy...
99 KB (10,732 words) - 13:28, 2 November 2024
with overlapping signs and symptoms. TSEs in non-human mammals include scrapie in sheep, bovine spongiform encephalopathy (BSE) in cattle – popularly...
39 KB (4,347 words) - 11:50, 22 October 2024
Major prion protein (section PrPSc (scrapie) isoform)
protease-resistant form designated PrPRes such as the disease-causing PrPSc (scrapie) and an isoform located in mitochondria. The misfolded version PrPSc is...
45 KB (5,140 words) - 15:40, 24 October 2024
either the remains of cattle who spontaneously developed the disease or scrapie-infected sheep products. The United Kingdom was afflicted with an outbreak...
63 KB (6,916 words) - 06:29, 19 October 2024
protein leading to a variety of spongiform encephalopathies such as kuru, scrapie and Creutzfeldt–Jakob disease. Ice VII, stable at room temperature but...
9 KB (1,149 words) - 21:06, 31 October 2024
the central nervous system in cattle. It is a fatal disease, similar to scrapie in sheep and goats, caused by a prion. A major epizootic affected the UK...
82 KB (11,301 words) - 12:54, 11 October 2024
astroglial hypertrophy in Scrapie, Kuru, Multiple Sclerosis and old age together with a note on the possible nature of the scrapie agent". Journal of Neurology...
35 KB (3,893 words) - 21:09, 28 October 2024
cow disease) in cattle, Creutzfeldt–Jakob disease (CJD) in humans, and scrapie in sheep. Natural infection causing CWD affects members of the deer family...
56 KB (6,547 words) - 22:32, 23 September 2024
clinical trial that attempted to eliminate scrapie from sheep by breeding out susceptibility to it. Scrapie can kill up to twenty-five percent of sheep...
50 KB (4,269 words) - 13:08, 13 September 2024
is a hypothetical infectious particle once theorized to be the cause of scrapie and other degenerative diseases of the central nervous system. It was thought...
5 KB (643 words) - 19:43, 12 May 2024
to study and develop scrapie-resistant sheep. An infectious, persistent, and spontaneous disease, animals infected with scrapie must be quarantined and...
12 KB (1,270 words) - 11:26, 28 July 2024
the possibility of transmission of scrapie, a deadly, degenerative prion disease of sheep and goats, though scrapie does not appear to be transmissible...
6 KB (537 words) - 03:02, 10 June 2024
among the first to find evidence indicating that the infectious agent in Scrapie does not contain nucleic acid: a finding that was instrumental in understanding...
12 KB (1,067 words) - 16:20, 4 January 2024
conditions that may affect their health. Some, like classical swine fever and scrapie are specific to one type of stock, while others, like foot-and-mouth disease...
69 KB (7,473 words) - 17:39, 17 October 2024
degenerative disease in humans. Kuru was shown to have remarkable similarity to scrapie, a disease of sheep and goats caused by an unconventional infectious agent...
18 KB (1,768 words) - 17:28, 23 August 2024
easily transmitted to pregnant women. Also of concern are the prion disease scrapie and the virus that causes foot-and-mouth disease (FMD), as both can devastate...
110 KB (12,738 words) - 15:07, 1 November 2024
uncertain function. They are the hypothesized cause of various TSEs, including scrapie in sheep, chronic wasting disease (CWD) in deer, bovine spongiform encephalopathy...
7 KB (839 words) - 14:55, 11 September 2024
In one-third of people with sporadic CJD, deposits of "prion protein (scrapie)", PrPSc, can be found in the skeletal muscle and/or the spleen. Diagnosis...
70 KB (7,661 words) - 01:26, 20 October 2024
conditions that may affect their health. Some, like classical swine fever and scrapie are specific to one population of animals, while others, like foot-and-mouth...
46 KB (5,375 words) - 03:21, 27 October 2024
his 1998 PNAS review article on Prions, Prusiner wrote: "The idea that scrapie prions were composed of an amyloidogenic protein was truly heretical when...
14 KB (1,151 words) - 04:03, 5 October 2024
to, Bovine spongiform encephalopathy (BSE) "Mad cow disease" in cattle, scrapie in sheep and goats, and Creutzfeldt–Jakob disease (CJD) in humans. Bastian...
5 KB (567 words) - 15:49, 1 April 2024
have spontaneously developed the disease as well as sheep infected with scrapie, a similar disease in sheep, the inclusion of brain and spinal cord tissue...
20 KB (2,078 words) - 17:51, 24 October 2024
although other reports have shown no significant effect, and treatment of scrapie in mice and sheep has also shown no effect. Possible reasons for the lack...
14 KB (1,455 words) - 16:11, 7 August 2024
hypersensitivity and inflammation. Hay mites are a suspected reservoir for scrapie, a prion disease of sheep. The mite Varroa destructor is a serious pest...
47 KB (4,996 words) - 10:24, 5 September 2024
mortality rate. Includes bovine spongiform encephalopathy (mad cow disease), scrapie, and kuru among others. Neonatal encephalopathy (hypoxic-ischemic encephalopathy):...
15 KB (1,591 words) - 00:44, 13 October 2024
animals Bovine spongiform encephalopathy Camel spongiform encephalopathy Scrapie Chronic wasting disease Transmissible mink encephalopathy Feline spongiform...
3 KB (255 words) - 22:38, 17 September 2024
pseudorabies eradication, swine brucellosis control/eradication, and voluntary scrapie flock certification program standards. UM&Rs usually are developed with...
1 KB (158 words) - 21:01, 8 September 2021
respiratory syncytial virus, Lyme disease, salmonella, mumps, measles, scrapie, dengue fever, and HIV. Routine diagnostic work with clinical specimens...
12 KB (1,336 words) - 04:10, 22 October 2024
Fibrils in brain of Rocky Mountain elk with chronic wasting disease contain scrapie amyloid. Guiroy DC, Williams ES, Song KJ, Yanagihara R, Gajdusek DC. Laboratory...
10 KB (1,157 words) - 22:59, 31 October 2024