MicroRNA (miRNA) are small, single-stranded, non-coding RNA molecules containing 21 to 23 nucleotides. Found in plants, animals and some viruses, miRNAs...
147 KB (16,686 words) - 08:00, 15 August 2024
MicroRNA sequencing (miRNA-seq), a type of RNA-Seq, is the use of next-generation sequencing or massively parallel high-throughput DNA sequencing to sequence...
49 KB (5,200 words) - 07:39, 12 December 2023
ribonucleic acid (RNA) molecules, microRNA (miRNA) and small interfering RNA (siRNA), are central to components to the RNAi pathway. Once mRNA is degraded,...
141 KB (15,474 words) - 08:09, 11 August 2024
RNAs such as microRNAs, siRNAs, piRNAs, snoRNAs, snRNAs, exRNAs, scaRNAs and the long ncRNAs such as Xist and HOTAIR. The number of non-coding RNAs within...
68 KB (7,253 words) - 04:01, 23 June 2024
Gene expression (redirect from RNA expression)
expression of microRNAs. In breast cancer, transcriptional repression of BRCA1 may occur more frequently by over-transcribed microRNA-182 than by hypermethylation...
102 KB (11,438 words) - 16:50, 17 July 2024
PMID 19765283. Thadani R, Tammi MT (December 2006). "MicroTar: predicting microRNA targets from RNA duplexes". BMC Bioinformatics. 7. 7 (Suppl 5): S20....
152 KB (8,425 words) - 03:34, 8 July 2024
Farrell, Jr. RNA Methodologies, 5th Edition. Academic Press, 2017 Brennecke J, Stark A, Russell RB, Cohen SM (March 2005). "Principles of microRNA-target recognition"...
49 KB (5,922 words) - 14:24, 18 August 2024
This microRNA database and microRNA targets databases is a compilation of databases and web portals and servers used for microRNAs and their targets....
22 KB (1,577 words) - 03:29, 3 December 2023
Glioblastoma (section MicroRNA)
the sinuous extracellular matrix of the brain. As of 2012, RNA interference, usually microRNA, was under investigation in tissue culture, pathology specimens...
78 KB (8,798 words) - 06:34, 17 August 2024
example is RNA interference (RNAi), in which endogenously expressed microRNA (miRNA) or exogenously derived small interfering RNA (siRNA) induces the...
47 KB (5,449 words) - 00:50, 6 August 2024
Regulus Therapeutics (section microRNA explained)
expression. Anti-miR therapeutics inhibit specific microRNA targets. Animal models showed that modulating microRNAs through anti-miRs effectively regulates biological...
5 KB (342 words) - 18:59, 4 July 2024
Short interspersed nuclear element (section microRNAs)
generate novel microRNA loci was analyzed. It was found that genes which were predicted to possess V-SINEs were targeted by microRNAs with significantly...
41 KB (5,252 words) - 08:25, 18 July 2024
Talaromyces marneffei (section MicroRNA-like RNAs)
suppression of RNA interference (RNAi)-related genes. Talaromyces marneffei dicer-dependent microRNA-like RNAs (milRNAs) were identified and these milRNAs were...
16 KB (1,983 words) - 18:39, 30 July 2024
levels. Using single-stranded RNA (ssRNA) fragments, such as microRNA (miRNA), or double-stranded small interfering RNA (siRNA), the complex functions as...
36 KB (3,836 words) - 14:30, 19 April 2024
molecular biology in May 2017. He defended his thesis, "Discovery of mature microRNA sequences within the protein-coding regions of global HIV-1 genomes: predictions...
31 KB (2,691 words) - 23:05, 17 August 2024
a number of specific microRNAs, when overexpressed, that directly reduce expression of specific DNA repair proteins (see MicroRNA section DNA repair and...
121 KB (13,581 words) - 14:59, 8 August 2024
Forensic serology (section Current research: microRNA)
used in many or all forensic labs. RSID Karl Landsteiner Paul Uhlenhuth microRNA Loop-mediated isothermal amplification Criminal Investigation by Ronald...
16 KB (2,156 words) - 20:25, 8 May 2024
encoding microRNA MicroRNA 106 MIR222: encoding microRNA MicroRNA 222 MIR223: encoding protein MicroRNA 223 MIR361: encoding microRNA MicroRNA 361 MIR503:...
42 KB (3,902 words) - 05:50, 15 August 2024
Gary Ruvkun (section microRNA, let-7)
by which lin-4, the first microRNA (miRNA) discovered by Victor Ambros, regulates the translation of target messenger RNAs via imperfect base-pairing...
24 KB (2,664 words) - 18:03, 29 April 2024
Cancer epigenetics (section MicroRNA gene silencing)
et al. (February 2013). "MicroRNA-182-5p targets a network of genes involved in DNA repair". RNA. 19 (2): 230–242. doi:10.1261/rna.034926.112. PMC 3543090...
111 KB (12,533 words) - 04:42, 11 August 2024
MicroRNA (miRNA) biosensors are analytical devices that involve interactions between the target miRNA strands and recognition element on a detection platform...
64 KB (7,163 words) - 19:55, 26 June 2024
transfer RNA (tRNA), microRNA (miRNA), small interfering RNA (siRNA), small nucleolar RNA (snoRNAs), Piwi-interacting RNA (piRNA), tRNA-derived small RNA (tsRNA)...
65 KB (7,606 words) - 20:16, 12 August 2024
body-specific RNA, by Dicer. This small RNA was found to function as a microRNA. Potential microRNAs were also identified in several other Human snoRNAs. Giardia...
5 KB (626 words) - 19:34, 28 August 2023
Dicer (category MicroRNA)
double-stranded RNA (dsRNA) and pre-microRNA (pre-miRNA) into short double-stranded RNA fragments called small interfering RNA and microRNA, respectively...
25 KB (3,219 words) - 05:09, 24 July 2024
interfering RNA (siRNA) and micro RNA (miRNA) to prevent mRNA translation and/or degrade mRNA. However, RNA aptamers are short, single stranded RNA molecules...
77 KB (8,886 words) - 09:03, 10 June 2024
Han J, Yeom KH, Lee S, Baek SH, Kim VN (October 2004). "MicroRNA genes are transcribed by RNA polymerase II". The EMBO Journal. 23 (20): 4051–4060. doi:10...
41 KB (4,799 words) - 19:34, 17 April 2024
P-bodies (section Associations with microRNA)
in general mRNA decay, nonsense-mediated mRNA decay, adenylate-uridylate-rich element mediated mRNA decay, and microRNA (miRNA) induced mRNA silencing....
28 KB (2,087 words) - 02:10, 8 July 2024
Regulation of gene expression (category RNA)
the gene. RNA can be an important regulator of gene activity, e.g. by microRNA (miRNA), antisense-RNA, or long non-coding RNA (lncRNA). LncRNAs differ from...
45 KB (5,235 words) - 16:05, 28 June 2024
Victor Ambros (section Discovery of microRNA)
an American developmental biologist who discovered the first known microRNA (miRNA). He is a professor at the University of Massachusetts Medical School...
12 KB (1,150 words) - 14:33, 12 October 2023
ncRNAs from small non-coding RNAs, such as microRNAs (miRNAs), small interfering RNAs (siRNAs), Piwi-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs)...
115 KB (12,353 words) - 08:50, 7 August 2024