Clozapine, sold under the brand name Clozaril among others, is a psychiatric medication and was the first atypical antipsychotic (also called second-generation...
136 KB (14,536 words) - 03:47, 26 October 2024
Clozapine N-oxide (CNO) is a synthetic drug used mainly in biomedical research as a ligand to activate Designer Receptors Exclusively Activated by Designer...
5 KB (470 words) - 17:37, 26 October 2024
antipsychotics, known as atypical antipsychotics, arrived with the introduction of clozapine in the early 1970s followed by others (e.g., risperidone). Both generations...
211 KB (18,597 words) - 03:51, 2 November 2024
risperidone and olanzapine; and produce weight gain similar to risperidone, clozapine and aripiprazole. They concluded that it produces suicide attempt, suicide;...
79 KB (6,427 words) - 19:30, 7 October 2024
member of the dibenzoxazepine class and structurally very similar to clozapine. Several researchers have argued that loxapine, initially classified as...
16 KB (1,076 words) - 08:02, 26 October 2024
a major active metabolite of the atypical antipsychotic drug clozapine. Unlike clozapine, it possesses intrinsic activity at the D2/D3 receptors, and...
7 KB (639 words) - 03:56, 26 October 2024
DHA-clozapine (tentative trade name Clozaprexin) is an atypical antipsychotic drug candidate that was created and originally tested by chemists at Protarga...
4 KB (151 words) - 03:59, 26 October 2024
quit before the 6-week completion date. Treatment with olanzapine (like clozapine) may result in increased weight gain and increased glucose and cholesterol...
97 KB (9,053 words) - 06:06, 31 October 2024
cases of bowel obstruction or constipation (such as those related to clozapine treatment) fecal vomiting has been identified as a cause of death. Fecal...
4 KB (338 words) - 03:12, 4 October 2024
Medications that can cause overproduction of saliva include: aripiprazole clozapine pilocarpine ketamine potassium chlorate risperidone pyridostigmine Substances...
6 KB (493 words) - 20:30, 16 August 2024
antipsychotics, in which case clozapine is offered. In a network comparative meta-analysis of 15 antipsychotic drugs, clozapine was significantly more effective...
173 KB (18,946 words) - 13:22, 4 November 2024
weeks to two of three different antipsychotics) in the remaining 20%. Clozapine is considered a first choice treatment for treatment resistant schizophrenia...
100 KB (9,276 words) - 00:58, 14 October 2024
and mirtazapine, and some antipsychotics. The atypical antipsychotic clozapine in particular is largely restricted to treatment-resistant cases and mandatory...
11 KB (1,105 words) - 00:46, 16 August 2024
vestibular branches of the eighth cranial nerve and to the renal tubules. Clozapine and latrepirdine are examples of drugs used in the treatment of CNS disorders...
8 KB (931 words) - 22:59, 9 August 2024
receptors (GPCR) engineered to respond exclusively to synthetic ligands, like clozapine N-oxide (CNO), and not to endogenous ligands. Several types of these receptors...
17 KB (1,944 words) - 19:49, 3 December 2023
with similar pharmacology and effects to the structurally related drug clozapine. It has two enantiomers, but has only been studied as the racemic mix...
2 KB (96 words) - 19:34, 6 April 2023
possible (although this may temporarily worsen symptoms) or switching to clozapine. Other medications such as valbenazine, tetrabenazine, or botulinum toxin...
37 KB (3,939 words) - 13:46, 1 November 2024
Examples of common anticholinergics: Antimuscarinic agents Antipsychotics (clozapine, quetiapine) Atropine Benztropine Biperiden Chlorpheniramine Certain SSRIs...
25 KB (2,388 words) - 05:24, 21 July 2024
rectifying potassium channel-specific: Barium Caramiphen Cloperastine Clozapine Dextromethorphan Ethosuximide Ifenprodil Tertiapin Tipepidine Activators...
181 KB (19,613 words) - 00:45, 31 October 2024
complications of the use of a number of different antipsychotics (most notably clozapine) which involves abnormalities in the composition of a person's blood (e...
30 KB (2,751 words) - 07:29, 22 October 2024
the effectiveness of clozapine in treating suicide attempts in patients with schizophrenia, which led to FDA approval of clozapine for treating suicide...
4 KB (354 words) - 08:14, 2 November 2024
Zuclopenthixol Atypical antipsychotics: Asenapine Clorotepine Clotiapine Clozapine DHA-clozapine Fluperlapine Iloperidone Norclozapine Norquetiapine Olanzapine...
42 KB (3,643 words) - 01:15, 16 September 2024
antipsychotics (e.g., aripiprazole, asenapine, brexpiprazole, cariprazine, clozapine, lurasidone, quetiapine, ziprasidone) Azapirones (e.g., buspirone, eptapirone...
166 KB (15,980 words) - 14:00, 3 November 2024
further understanding of the use of clozapine. In 2022 he suggested a refined phenotype for genetic studies into clozapine-related agranulocytosis. He has...
20 KB (1,933 words) - 09:18, 31 July 2024
antipsychotics (e.g., aripiprazole, asenapine, brexpiprazole, cariprazine, clozapine, lurasidone, quetiapine, ziprasidone) Azapirones (e.g., buspirone, eptapirone...
37 KB (4,010 words) - 17:19, 13 October 2024
lauroxil Brilaroxazine†Brexpiprazole Cariprazine Tricyclics: Asenapine Clozapine# Olanzapine (+samidorphan) Quetiapine Zotepine Others: Blonanserin Pimavanserin...
63 KB (5,592 words) - 05:40, 28 October 2024
episodes in the wake of psychotic medication withdrawal associated with Clozapine, rather than on medication resistance. A hypothetical condition related...
4 KB (489 words) - 15:44, 2 November 2024
physical forms for clozapine as compared to 60 distinct physical forms for olanzapine. The experimental screening results of clozapine are consistent with...
47 KB (5,152 words) - 06:28, 16 October 2024
Anisodamine Anisodine Atiprosin Atypical antipsychotics (e.g., brexpiprazole, clozapine, olanzapine, quetiapine, risperidone) Benoxathian Beta blockers (e.g....
33 KB (2,908 words) - 03:30, 7 September 2024
CDD-0078 CDD-0097 CDD-0098 CDD-0102 Cevimeline Choline cis-Dioxolane Clozapine Desmethylclozapine (norclozapine) Ethoxysebacylcholine Itameline LY-593...
34 KB (3,196 words) - 23:59, 14 October 2024