• Thumbnail for Suvorexant
    enzoxazolyl)hexahydro-7-methyl-1H-1,4-diazepin-1-yl][5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]methanone. Its molecular formula is C23H23N6O2Cl and its...
    94 KB (8,941 words) - 16:56, 16 September 2024
  • The triazol-5-ylidenes are a group of persistent carbenes which includes the 1,2,4-triazol-5-ylidene system and the 1,2,3-triazol-5-ylidene system. As...
    22 KB (2,758 words) - 23:40, 9 December 2023
  • Thumbnail for Persistent carbene
    nitrogen atoms in triazol-5-ylidene, there are two possible isomers, namely 1,2,3-triazol-5-ylidenes and 1,2,4-triazol-5-ylidenes. The triazol-5-ylidenes based...
    62 KB (6,933 words) - 11:59, 13 August 2024
  • Thumbnail for Daridorexant
    -1H-benzo[d]imidazol-2-yl)-2-methylpyrrolidin-1-yl)(5-methoxy-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone. Its molecular formula is C23H23N6O2Cl and its...
    48 KB (4,078 words) - 11:27, 24 July 2024
  • Thumbnail for Seltorexant
    6-Dimethylpyrimidin-2-yl)-hexahydropyrrolo[3,4-c]pyrrol-2-yl]-(2-fluoro-6-[1,2,3]triazol-2-ylphenyl)methanone CAS Number 1293281-49-8 Y PubChem CID 67116280...
    7 KB (498 words) - 08:59, 15 September 2024
  • Also well studied are the mesoionic carbenes based on 1,2,3-triazole, referred to as 1,2,3-triazol-4(or 5)-ylidenes. The first triazolylidenes were reported...
    16 KB (2,062 words) - 07:46, 10 October 2022
  • Thumbnail for Milvexian
    1 h Identifiers IUPAC name (9R,13S)-13-{4-[5-Chloro-2-(4-chloro-1H-1,2,3-triazol-1-yl)phenyl]-6-oxo-1(6H)-pyrimidinyl}-3-(difluoromethyl)-9-methyl-3...
    4 KB (173 words) - 05:43, 28 June 2023
  • Thumbnail for Tazobactam
    ℞ (Prescription only) Identifiers IUPAC name (2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide...
    3 KB (144 words) - 21:30, 14 August 2023
  • Thumbnail for Tris(benzyltriazolylmethyl)amine
    Tris((1-benzyl-4-triazolyl)methyl)amine (TBTA) is a tertiary amine containing the 1,2,3-triazole moiety. When used as a ligand, complexed to copper(I), it allows...
    4 KB (279 words) - 02:00, 22 August 2022
  • couplings. Interesting examples of abnormal NHCs are based on the mesoionic 1,2,3-triazol-5-ylidene structure. An efficient, cationic palladium catalyst of PEPPSI...
    48 KB (5,443 words) - 08:05, 6 June 2024
  • Thumbnail for PEPPSI
    PEPPSI catalysts. Examples of abnormal NHCs based on the mesoionic 1,2,3-triazol-5-ylidene structure have been used for palladium catalysis. In this...
    14 KB (1,406 words) - 10:53, 26 April 2023
  • "3-(2-Amino-6-(1-((6-(2-hydroxypropan-2-yl)pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)pyrimidin-4-yl)-2-methylbenzonitrile". pubchem.ncbi.nlm.nih.gov...
    5 KB (492 words) - 03:33, 27 August 2024
  • Thumbnail for Solithromycin
    name (3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-[4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl]-4-ethyl-7-fluorooctahydro-11-methoxy-3a,7,9,11,13,15-hexamethyl-10-{[3...
    16 KB (1,416 words) - 15:10, 24 January 2024
  • Thumbnail for ACT-539313
    PMC 7319015. PMID 32067262. ACT-539313 ((4-methyl-2-[1,2,3]triazol-2-yl-phenyl)-[(R)- 3-(3-[1,2,3]triazol-2-yl-benzyl)-morpholin-4-yl]-methanone) is an orally...
    6 KB (402 words) - 20:39, 1 December 2023
  • Thumbnail for Radezolid
    "Synthesis of an antibacterial compound containing a 1,4-substituted 1H-1,2,3-triazole- a scaleable [sic?] alternative to the "click" reaction"". Organic...
    3 KB (268 words) - 14:26, 8 January 2023
  • Thumbnail for BOP reagent
    BOP reagent Names IUPAC name ((1H-Benzo[d][1,2,3]triazol-1-yl)oxy)tris(dimethylamino)phosphonium hexafluorophosphate(V) Other names Castro's reagent Identifiers...
    5 KB (323 words) - 16:01, 3 August 2024
  • Guisado-Barrios, J. Bouffard, B. Donnadieu, G. Bertrand, « Crystalline 1H-1,2,3-Triazol-5-ylidenes: New Stable Mesoionic Carbenes (MICs) », Angew. Chem. Int...
    20 KB (1,578 words) - 01:28, 1 July 2024
  • Thumbnail for Tradipitant
    IUPAC name (2-(1-(3,5-Bis(trifluoromethyl)benzyl)-5-(pyridin-4-yl)-1H-1,2,3-triazol-4-yl)pyridin-3-yl)(2-chlorophenyl)methanone CAS Number 622370-35-8 PubChem...
    7 KB (491 words) - 15:12, 3 December 2023
  • Thumbnail for Metabotropic glutamate receptor 1
    glutamate receptor 1 antagonist, 4-[1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine-1(2H)-carboxamide (FTIDC)"...
    22 KB (2,342 words) - 08:11, 10 March 2024
  • Thumbnail for Cefatrizine
    7R)-7-{[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino}-8-oxo-3-[(1H-1,2,3-triazol-4-ylsulfanyl)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic...
    3 KB (56 words) - 01:49, 24 January 2023
  • Thumbnail for Cefmatilen
    7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)- 2-(hydroxyimino)acetyl]amino}-8-oxo-3-{[(1H-1,2,3- triazol-4-ylsulfanyl)methyl]sulfanyl}-5-thia-1- azabicyclo[4.2.0]oct-2-ene-2-carboxylic...
    3 KB (116 words) - 22:16, 29 January 2023
  • Thumbnail for Α5IA
    5h Identifiers IUPAC name 3-(5-methylisoxazol-3-yl)-6-[(1-methyl-1H-1,2,3-triazol-4-yl)methoxy][1,2,4]triazolo[3,4-a]phthalazine CAS Number 215874-86-5...
    5 KB (344 words) - 21:12, 28 August 2024
  • Thumbnail for Otto Dimroth
    "Ueber intramolekulare Umlagerungen. Umlagerungen in der Reihe des 1, 2, 3-Triazols". Justus Liebig's Annalen der Chemie. 364 (2): 183–226. doi:10.1002/jlac...
    3 KB (186 words) - 21:37, 16 February 2023
  • Ueber intramolekulare Umlagerungen. Umlagerungen in der Reihe des 1, 2, 3-Triazols Justus Liebig's Annalen der Chemie Volume 364, Issue 2, Date: 1909, Pages:...
    2 KB (253 words) - 19:36, 27 October 2022
  • Thumbnail for List of benzodiazepines
    4]diazepin-2(3H)-one 21738192 Compound 6a 9.5 † 7-chloro-5-(3,5-dimethyl-4H-1,2,4-triazol-4-yl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one JC-184 7-bromo-5-(2-thienyl)-1H-benzo[e]...
    108 KB (3,088 words) - 07:42, 22 July 2024
  • Thumbnail for Seviteronel
    Moore WR, Schotzinger RJ, Hoekstra WJ (June 2014). "Highly-selective 4-(1,2,3-triazole)-based P450c17a 17,20-lyase inhibitors". Bioorganic & Medicinal...
    11 KB (882 words) - 12:00, 13 July 2024