• Thumbnail for Deprenyl
    Xylopropamine Zylofuramine Piperazines: 2C-B-BZP BZP MBZP MDBZP MeOPP oMPP Others: 2-ADN 2-AI 2-AT 4-BP 5-APDI 5-IAI Amineptine Clofenciclan Cyclopentamine Cypenamine...
    7 KB (517 words) - 21:14, 17 October 2024
  • Thumbnail for List of dopaminergic drugs
    (MDBZP, piperonylpiperazine) Others: 2-Amino-1,2-dihydronaphthalene (2-ADN) • 2-Aminoindane (2-AI) • 2-Aminotetralin (2-AT) • 4-Benzylpiperidine (4-BP) •...
    17 KB (998 words) - 02:33, 9 November 2024
  • Thumbnail for Phenylephrine
    phenylephrine is not a catecholamine, and is not metabolized by catechol O-methyltransferase (COMT). Besides monoamine oxidase, phenylephrine is also metabolized...
    57 KB (5,015 words) - 20:24, 16 December 2024
  • Thumbnail for Methamphetamine
    among others. ΔJunD, a transcription factor, and G9a, a histone methyltransferase enzyme, both directly oppose the induction of ΔFosB in the nucleus...
    163 KB (15,931 words) - 20:58, 22 December 2024
  • Thumbnail for Serotonin
    blocked by an N-methyltransferase inhibitor that prevents the metabolism of 5-HTP to N-methyltryptamines (50). Inhibition of N-methyltransferase failed to block...
    157 KB (16,651 words) - 12:38, 4 December 2024
  • Thumbnail for N,N-Dimethyltryptamine
    undergoes a transmethylation (step 2): the enzyme indolethylamine-N-methyltransferase (INMT) catalyzes the transfer of a methyl group from cofactor S-adenosylmethionine...
    159 KB (15,313 words) - 03:08, 20 December 2024
  • Thumbnail for N-Methyltryptamine
    in humans from tryptamine by certain N-methyltransferase enzymes, such as indolethylamine N-methyltransferase. It is a known component in human urine...
    8 KB (643 words) - 09:14, 2 November 2024
  • Thumbnail for Α-Methylphenylalanine
    Xylopropamine Zylofuramine Piperazines: 2C-B-BZP BZP MBZP MDBZP MeOPP oMPP Others: 2-ADN 2-AI 2-AT 4-BP 5-APDI 5-IAI Amineptine Clofenciclan Cyclopentamine Cypenamine...
    7 KB (504 words) - 15:00, 8 October 2024
  • Thumbnail for Pseudoephedrine
    metabolized by this enzyme. It is also not metabolized by catechol O-methyltransferase (COMT). Pseudoephedrine is demethylated into the metabolite norpseudoephedrine...
    148 KB (13,448 words) - 02:31, 27 December 2024
  • Thumbnail for Pharmacology of selegiline
    Xylopropamine Zylofuramine Piperazines: 2C-B-BZP BZP MBZP MDBZP MeOPP oMPP Others: 2-ADN 2-AI 2-AT 4-BP 5-APDI 5-IAI Amineptine Clofenciclan Cyclopentamine Cypenamine...
    139 KB (14,124 words) - 07:48, 1 January 2025
  • Thumbnail for Desmethylselegiline
    Xylopropamine Zylofuramine Piperazines: 2C-B-BZP BZP MBZP MDBZP MeOPP oMPP Others: 2-ADN 2-AI 2-AT 4-BP 5-APDI 5-IAI Amineptine Clofenciclan Cyclopentamine Cypenamine...
    19 KB (1,485 words) - 00:57, 20 August 2024
  • Thumbnail for Α-Methyltryptamine
    Xylopropamine Zylofuramine Piperazines: 2C-B-BZP BZP MBZP MDBZP MeOPP oMPP Others: 2-ADN 2-AI 2-AT 4-BP 5-APDI 5-IAI Amineptine Clofenciclan Cyclopentamine Cypenamine...
    44 KB (3,832 words) - 13:13, 8 December 2024
  • Thumbnail for MDMA
    metabolic pathways: (1) O-demethylenation followed by catechol-O-methyltransferase (COMT)-catalyzed methylation and/or glucuronide/sulfate conjugation;...
    195 KB (18,339 words) - 00:36, 30 December 2024
  • Thumbnail for Α-Methyl-5-hydroxytryptophan
    Xylopropamine Zylofuramine Piperazines: 2C-B-BZP BZP MBZP MDBZP MeOPP oMPP Others: 2-ADN 2-AI 2-AT 4-BP 5-APDI 5-IAI Amineptine Clofenciclan Cyclopentamine Cypenamine...
    10 KB (786 words) - 08:21, 11 November 2024
  • Thumbnail for Adderall
    among others. ΔJunD, a transcription factor, and G9a, a histone methyltransferase enzyme, both oppose the function of ΔFosB and inhibit increases in...
    63 KB (22,402 words) - 14:38, 3 January 2025
  • Thumbnail for Dopaminergic
    deficits associated with schizophrenia: potential role of catechol-O-methyltransferase inhibitors". CNS Drugs. 21 (7): 535–557. doi:10.2165/00023210-200721070-00002...
    28 KB (2,798 words) - 01:21, 21 November 2024
  • Thumbnail for Tyramine
    Xylopropamine Zylofuramine Piperazines: 2C-B-BZP BZP MBZP MDBZP MeOPP oMPP Others: 2-ADN 2-AI 2-AT 4-BP 5-APDI 5-IAI Amineptine Clofenciclan Cyclopentamine Cypenamine...
    29 KB (2,686 words) - 15:45, 5 January 2025
  • Thumbnail for Α-Ethyltryptamine
    Xylopropamine Zylofuramine Piperazines: 2C-B-BZP BZP MBZP MDBZP MeOPP oMPP Others: 2-ADN 2-AI 2-AT 4-BP 5-APDI 5-IAI Amineptine Clofenciclan Cyclopentamine Cypenamine...
    32 KB (2,526 words) - 05:08, 6 January 2025
  • Thumbnail for Amphetamine
    among others. ΔJunD, a transcription factor, and G9a, a histone methyltransferase enzyme, both oppose the function of ΔFosB and inhibit increases in...
    279 KB (29,422 words) - 04:46, 6 January 2025
  • Thumbnail for Para-Methoxy-N-methylamphetamine
    Xylopropamine Zylofuramine Piperazines: 2C-B-BZP BZP MBZP MDBZP MeOPP oMPP Others: 2-ADN 2-AI 2-AT 4-BP 5-APDI 5-IAI Amineptine Clofenciclan Cyclopentamine Cypenamine...
    18 KB (1,483 words) - 13:30, 8 December 2024
  • Thumbnail for SU-11739
    Xylopropamine Zylofuramine Piperazines: 2C-B-BZP BZP MBZP MDBZP MeOPP oMPP Others: 2-ADN 2-AI 2-AT 4-BP 5-APDI 5-IAI Amineptine Clofenciclan Cyclopentamine Cypenamine...
    7 KB (534 words) - 07:05, 1 October 2024
  • Thumbnail for Trace amine
    can also be converted by nonspecific N-methyltransferase (NMT) [22] and phenylethanolamine N-methyltransferase (PNMT) [23] to the corresponding secondary...
    20 KB (2,302 words) - 02:01, 24 November 2024
  • Thumbnail for 4-Methylthioamphetamine
    Xylopropamine Zylofuramine Piperazines: 2C-B-BZP BZP MBZP MDBZP MeOPP oMPP Others: 2-ADN 2-AI 2-AT 4-BP 5-APDI 5-IAI Amineptine Clofenciclan Cyclopentamine Cypenamine...
    19 KB (1,945 words) - 13:31, 8 December 2024
  • Thumbnail for Selegiline
    Xylopropamine Zylofuramine Piperazines: 2C-B-BZP BZP MBZP MDBZP MeOPP oMPP Others: 2-ADN 2-AI 2-AT 4-BP 5-APDI 5-IAI Amineptine Clofenciclan Cyclopentamine Cypenamine...
    208 KB (20,191 words) - 07:42, 6 January 2025
  • Thumbnail for Dextroamphetamine
    among others. ΔJunD, a transcription factor, and G9a, a histone methyltransferase enzyme, both oppose the function of ΔFosB and inhibit increases in...
    64 KB (21,462 words) - 23:47, 4 January 2025
  • Thumbnail for Phenethylamine
    30 seconds. In humans, PEA is metabolized by phenylethanolamine N-methyltransferase (PNMT), monoamine oxidase A (MAO-A), monoamine oxidase B (MAO-B),...
    54 KB (5,178 words) - 08:03, 6 January 2025
  • Thumbnail for Naphthylaminopropane
    analogues include 2-aminotetralin (2-AT), 2-amino-1,2-dihydronaphthalene (2-ADN), 1-phenylpiperazine (1-PP), 2-aminoindane (2-AI), 6-ABTooltip 6-amino-6...
    15 KB (1,396 words) - 07:53, 9 December 2024
  • Thumbnail for Phenylpropanolamine
    (MAOs). Phenylpropanolamine is also not a substrate of catechol O-methyltransferase. The hydroxyl group at the β carbon of phenylpropanolamine also helps...
    55 KB (5,794 words) - 07:22, 21 December 2024
  • Thumbnail for Bufotenin
    body. It can be biosynthesized from serotonin by indolethylamine N-methyltransferase (INMT) enzymes. A study conducted in the late 1960s reported the detection...
    44 KB (4,469 words) - 02:35, 17 November 2024
  • Thumbnail for Para-Methoxyamphetamine
    Xylopropamine Zylofuramine Piperazines: 2C-B-BZP BZP MBZP MDBZP MeOPP oMPP Others: 2-ADN 2-AI 2-AT 4-BP 5-APDI 5-IAI Amineptine Clofenciclan Cyclopentamine Cypenamine...
    33 KB (3,273 words) - 19:27, 23 December 2024