ALC-0315 ([(4-hydroxybutyl)azanediyl]di(hexane-6,1-diyl) bis(2-hexyldecanoate)) is a synthetic lipid. A colorless oily material, it has attracted attention...
8 KB (782 words) - 12:58, 24 January 2024
tozinameran. Pfizer–BioNTech COVID-19 vaccine nanoparticle ingredients ALC-0315 1,2-distearoyl-sn-glycero-3-phosphocholine Cholesterol Others Polyethoxylated...
2 KB (205 words) - 21:16, 8 February 2024
while Pfizer and BioNTech licensed an ionizable cationic lipid called ALC-0315 from Acuitas. Elucidation of intestinal lymphatic absorption mechanism...
24 KB (2,687 words) - 18:59, 5 October 2024
method of transfection. In humans, the cationic lipids SM-102, ALC-0159 and ALC-0315 are used in conjunction with electrically neutral helper lipids...
8 KB (1,186 words) - 05:09, 11 June 2024
bromo ester. HO(CH2)2NH(CH2)7CO2CH(C8H17)2 + Br(CH2)5CO2C11H23 → SM-102 ALC-0315 Moderna COVID-19 vaccine nanoparticle ingredients Distearoylphosphatidylcholine...
7 KB (628 words) - 18:17, 27 March 2024
Pfizer/BioNTech covid vaccines employ ALC-0315 lipid from Acuitas Therapeutics and formulate it with cholesterol, DSPC, and a PEG-Lipid (ALC-0159) together with mRNA...
78 KB (8,788 words) - 19:06, 6 August 2024
inactive ingredients (excipients): ALC-0315, ((4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate) ALC-0159, 2-[(polyethylene glycol)-2000]-N...
260 KB (22,082 words) - 05:55, 13 September 2024