In molecular biology, a stop codon (or termination codon) is a codon (nucleotide triplet within messenger RNA) that signals the termination of the translation...
30 KB (2,789 words) - 10:55, 5 June 2024
different codons in the genetic code and the below tables; most specify an amino acid. Three sequences, UAG, UGA, and UAA, known as stop codons, do not...
42 KB (1,588 words) - 15:30, 21 August 2024
Nonsense mutation (redirect from Premature stop codon)
point mutation in a sequence of DNA that results in a nonsense codon, or a premature stop codon in the transcribed mRNA, and leads to a truncated, incomplete...
25 KB (2,870 words) - 22:43, 9 March 2024
Genetic code (redirect from Codon)
out of 64 codons in their experiments. Khorana, Holley and Nirenberg received the Nobel Prize (1968) for their work. The three stop codons were named...
73 KB (8,048 words) - 09:11, 25 May 2024
variant that causes loss of a stop codon Stop-Loss (film), a 2008 film about soldiers subject to the stop-loss policy "Stop-Loss" (Dollhouse), an episode...
781 bytes (130 words) - 03:12, 29 December 2023
The start codon is the first codon of a messenger RNA (mRNA) transcript translated by a ribosome. The start codon always codes for methionine in eukaryotes...
16 KB (1,860 words) - 02:18, 24 January 2024
reading frames are defined as spans of DNA sequence between the start and stop codons. Usually, this is considered within a studied region of a prokaryotic...
16 KB (1,898 words) - 09:12, 17 March 2024
termination of translation (stop codons). There are 64 different codons (61 codons encoding for amino acids and 3 stop codons) but only 20 different translated...
28 KB (3,178 words) - 18:48, 13 August 2024
Expanded genetic code (section Codon assignment)
number of 64 codons in the bacterial genome to 61 codons (eliminating two out of the six codons coding for serine and one out of three stop codons) – of which...
79 KB (9,132 words) - 14:42, 26 June 2024
moves to the next mRNA codon to continue the process (translocation), creating an amino acid chain. Termination: When a stop codon is reached, the ribosome...
35 KB (4,020 words) - 20:00, 17 August 2024
Degeneracy or redundancy of codons is the redundancy of the genetic code, exhibited as the multiplicity of three-base pair codon combinations that specify...
7 KB (905 words) - 22:03, 10 May 2024
Non-stop decay (NSD) is a cellular mechanism of mRNA surveillance to detect mRNA molecules lacking a stop codon and prevent these mRNAs from translation...
7 KB (1,014 words) - 04:04, 10 June 2023
Transfer RNA (redirect from Anti codon)
tRNA specifies which three-nucleotide codon from the genetic code corresponds to which amino acid. Each mRNA codon is recognized by a particular type of...
63 KB (7,572 words) - 19:54, 15 August 2024
nearby UGA codon as selenocysteine (UGA is normally a stop codon). In some methanogenic prokaryotes, the UAG codon (normally a stop codon) can also be...
38 KB (1,631 words) - 11:23, 12 April 2024
skull Stop codon, a type of RNA molecule in genetic code STOP protein, a protein in animals Surgical termination of pregnancy, a type of abortion Stop consonant...
5 KB (687 words) - 13:42, 10 August 2024
Frameshift mutation (section Codon-triplet importance)
reading of the codons after the mutation to code for different amino acids. The frameshift mutation will also alter the first stop codon ("UAA", "UGA"...
36 KB (4,730 words) - 03:35, 14 August 2024
gene expression by eliminating mRNA transcripts that contain premature stop codons. Translation of these aberrant mRNAs could, in some cases, lead to deleterious...
23 KB (2,900 words) - 08:39, 17 August 2024
as codons. The set of three nucleotides almost always produce the same amino acid with a few exceptions like UGA which typically serves as the stop codon...
27 KB (3,320 words) - 14:25, 5 August 2024
as stop codons, indicating that translation should stop), some amino acids are coded for by 2, 3, 4, or 6 different codons. For example, the codons TTT...
9 KB (1,121 words) - 15:46, 8 November 2023
encoded by the stop codons—TGA and TAG respectively.) The mismatch between the number of codons and amino acids allows several codons to code for a single...
19 KB (2,014 words) - 22:06, 8 April 2024
Amino acid (redirect from Codon alphabet)
includes a SECIS element, which causes the UGA codon to encode selenocysteine instead of a stop codon. Pyrrolysine is used by some methanogenic archaea...
98 KB (10,138 words) - 04:23, 20 August 2024
codon) then a different tRNA is required for that anticodon. The minimum requirement to satisfy all possible codons (61 excluding three stop codons)...
13 KB (1,455 words) - 00:38, 1 July 2024
a codon is changed to a premature stop codon that results in truncation of the resulting protein, and the nonstop mutations, in which a stop codon erasement...
7 KB (804 words) - 04:06, 1 April 2024
Split gene theory (section Stop codons are key parts of every genetic element in the eukaryotic gene)
important intron structures and regulatory sequences are derived from stop codons. In this introns-first framework, the spliceosomal machinery and the...
69 KB (8,037 words) - 13:18, 18 August 2024
nascent polypeptide chain when the ribosome encounters a stop codon. While eRF1 recognizes stop codons, eRF3 facilitates the release of the polypeptide chain...
8 KB (1,026 words) - 21:49, 23 September 2022
"Consensus" is defined as protein-coding regions that agree at the start codon, stop codon, and splice junctions, and for which the prediction meets quality...
28 KB (2,912 words) - 17:28, 5 March 2024
The mold, protozoan, and coelenterate mitochondrial code and the mycoplasma/spiroplasma code (section Alternative initiation codons)
with slight variations, notably the use of UGA as a tryptophan codon rather than a stop codon. AAs = FFLLSSSSYY**CCWWLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG...
6 KB (551 words) - 15:11, 4 May 2023
for the termination of translation by recognizing the termination codon or stop codon in an mRNA sequence. They are named so because they release new peptides...
14 KB (1,728 words) - 17:55, 10 July 2024
cannot be equal. Additionally, it is usual to use degenerate codons that minimise stop codons (which are generally not desired). Consequently, the fully...
7 KB (732 words) - 02:18, 2 July 2024
Terminator (genetics) (redirect from Codon, terminator)
phages. The Rho-dependent terminator occurs downstream of translational stop codons and consists of an unstructured, cytosine-rich sequence on the mRNA known...
13 KB (1,631 words) - 10:55, 5 June 2024