A cytokine storm, also called hypercytokinemia, is a pathological reaction in humans and other animals in which the innate immune system causes an uncontrolled...

Cytokines (/'saɪ.tə.kaɪn/) are a broad and loose category of small proteins (~5–25 kDa) important in cell signaling. Due to their size, cytokines cannot...

refers to cytokine storm syndromes (CSS) and occurs when large numbers of white blood cells are activated and release inflammatory cytokines, which in...

ferritin blood test to identify a cytokine storm (also called cytokine storm syndrome, not to be confused with cytokine release syndrome), it is meant to...

macrophages that secrete high amounts of inflammatory cytokines. It is classified as one of the cytokine storm syndromes. There are inherited and non-inherited...

major role in COVID-19 morbidity. In severe cases, COVID-19 causes a cytokine storm which contributes to excessive and uncontrolled inflammation of organs...

death in animal models of cytokine storm. As a repurposed drug, prazosin is being investigated for the prevention of cytokine storm syndrome and complications...

"Famotidine activates the vagus nerve inflammatory reflex to attenuate cytokine storm". Mol Med. 28 (1): 57. doi:10.1186/s10020-022-00483-8. PMC 9109205....

and organ failure. It is a subset of cytokine storm, in which there is abnormal regulation of various cytokines. SIRS is also closely related to sepsis...

COVID-19 patients may lead to the initiation of the cytokine storm. This excess release of cytokines may lead to myocardial injury. In addition to direct...

expected to possess anti-inflammatory properties that could lessen the cytokine storm associated with a SARS-CoV-2 infection, but the trials did not demonstrate...

Pinto AC, Santos RR, Rocha AP, et al. (29 June 2021). "Biomarkers of cytokine storm as red flags for severe and fatal COVID-19 cases: A living systematic...

remains today. Fajgenbaum is the founding director of the Center for Cytokine Storm Treatment & Laboratory, which is focused on unlocking the unknowns of...

CEO of StormBio, Inc, a development stage biotechnology company focused on the attenuation of Cytokine Storm, specifically in influenza. StormBio was...

pro-inflammatory response called a cytokine storm. Infection with H5N1 or H7N9 especially produces high levels of pro-inflammatory cytokines. In bacterial infections...

cells and macrophages to rapidly multiply and activate, resulting in a "cytokine storm." The cause of sJIA is currently unknown. While infectious organisms...

IL-1 family members, her recent work on cytokine storm established TNF and IFN-γ as the key upstream cytokines that cause inflammatory cell death (PANoptosis)...

changes) can cause MCD in a fraction of patients by producing cytokines that initiate a cytokine storm. In patients who have both POEMS-associated MCD, treatment...

well as differentiation of B cells and T cells progressing towards cytokine storm. Since excessive JAK-STAT signalling is responsible for some cancers...

Rowe, Jared; Sundel, Robert P. (2019-02-14). "Calm in the midst of cytokine storm: a collaborative approach to the diagnosis and treatment of hemophagocytic...

overreacting in a potentially fatal cytokine storm. Oldstone, with his colleague Hugh Rosen, studied the cytokine storm provoked in mice and ferrets by infection...

impact on reducing cytokine storms, further studies did not confirm this expected benefit on COVID-19 patients. A cytokine storm refers to an excessive...

and to survive. This is consistent with the frequent development of a cytokine storm in the affected. Few persons over 50 years of age seem to have become...

"Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology". Seminars in Immunopathology. 39 (5): 529–539....

toll-like receptor 4 resulting in what is known as a cytokine storm or a thrombotic storm. A thrombotic storm may also occur due to the following precipitating...

damage to host tissues while the infection is being countered (e.g., cytokine storm). The virulence factors of bacteria are typically proteins or other...

society Cancer-specific survival, survival rates specific to cancer type Cytokine storm syndrome Churg–Strauss syndrome, a type of autoimmune vasculitis, also...

and "strawberry tongue". Various mental disturbances are possible. A cytokine storm may take place, in which the child's innate immune system stages an...

disease course are caused by systemic hyper-inflammation, the so-called cytokine storm. Although several medications have been approved in different countries...

Janus kinase-1/2 inhibitor targeting viral entry, replication and the cytokine storm, and is associated with beneficial outcomes including in severely ill...