Forkhead box protein N1 is a protein that in humans is encoded by the FOXN1 gene. Mutations in the winged-helix transcription factor gene at the nude...

tumors. The genetic basis of the nude mouse mutation is a disruption of the FOXN1 gene. The nomenclature for the nude mouse has changed several times since...

all stages of TEC development in embryonic and postnatal thymus is a Foxn1. Foxn1 controls the whole process by the activation of its target genes with...

(IL7Rα), DCLRE1C-Artemis, RMRP-CHH, DNA-Ligase IV, common gamma chain, WHN-FOXN1, ZAP-70 and complete DiGeorge syndrome. It is fatal without treatment. The...

IL-2, adrenal) FOXL1 (ovary), FOXL2 FOXM1 (cell cycle, erythroid, cancer) FOXN1 (hair, thymus), FOXN2, FOXN3 (cell cycle checkpoints; widely expressed)...

and fungi. Nude mice with the very rare "nude" deficiency as a result of FOXN1 mutation are a strain of research mice as a model of T cell deficiency....

knockout model of nude mice with deficiency of Foxn-1 gene it is obvious that Foxn1 transcriptional factor is involved in specific expression of β5t in thymus...

Known motif – from protein with 100% identical DBD – in vitro [271] RWHR FOXN1 ENSG00000109101 Forkhead Known motif – In vivo/Misc source [272] WVBSACGCB...

CC (September 2014). "An organized and functional thymus generated from FOXN1-reprogrammed fibroblasts". Nature Cell Biology. 16 (9): 902–908. doi:10...

strands during the development of T cells and B cells. A mutation in the Foxn1 gene on chromosome 11 resulted in impaired thymus development, leading to...

Q6ZUU3 5813 FOXL3 HGNC:54201 A0A1W2PRP0 5814 FOXM1 HGNC:3818 Q08050 5815 FOXN1 HGNC:12765 O15353 5816 FOXN2 HGNC:5281 P32314 5817 FOXN3 HGNC:1928 O00409...

development is Forkhead Box N1 (FOXN1). As a member of the transcription factor family known as the forkhead box gene family, FOXN1 plays a role in the growth...

CC (September 2014). "An organized and functional thymus generated from FOXN1-reprogrammed fibroblasts". Nature Cell Biology. 16 (9): 902–908. doi:10...

deficiency CHARGE syndrome (CHD7 deficiency or SEMA3E deficiency) Winged helix/FOXN1 deficiency Chromosome 10p13-p14 deletion Immuno-osseous dysplasias (abnormal...

of somatic stem cells into cardiomyocytes. Thymus Induced Up regulating FOXN1, which causes increased expression of thymic epithelial cell specific receptor...

have been shown to control hair follicle development as well. HOXC13 and FOXN1 are considered important regulators because loss-of-function experiments...

Clare (September 2014). "An organized and functional thymus generated from FOXN1-reprogrammed fibroblasts". Nature Cell Biology. 16 (9): 902–908. doi:10...

cells (mTECs). Conditional deletion of Ikzf1 in thymic epithelial cells by Foxn1-Cre in mice, results in the dysregulation of various mTEC subsets, including...

(2007). "Diagnostic utility of thymic epithelial markers CD205 (DEC205) and Foxn1 in thymic epithelial neoplasms". Am. J. Surg. Pathol. 31 (7): 1038–44. doi:10...

Hofmann, Thomas G.; Kyewski, Bruno (August 2014). "Adult Thymus Contains FoxN1− Epithelial Stem Cells that Are Bipotent for Medullary and Cortical Thymic...

used. Thymus transplantation can also be used in pediatric patients with a Foxn1 deficiency. In the 2000s, promising animal experiments into transplanting...

S, Brunk F, Hofmann TG, Kyewski B (August 2014). "Adult thymus contains FoxN1(-) epithelial stem cells that are bipotent for medullary and cortical thymic...

T-cell immunodeficiency, congenital alopecia, and nail dystrophy; 601705; FOXN1 Testicular microlithiasis; 610441; SLC34A2 Testicular tumor, sporadic; 273300;...

Catherine Clare (2014). "An organized and functional thymus generated from FOXN1-reprogrammed fibroblasts". Nature Cell Biology. 16 (9): 902–908. doi:10...